Development Level

Tbio 96 | 11,445
Tchem 15 | 1,598
Tclin 12 | 613

IMPC Phenotype

preweaning lethality, complete... 8 | 979
increased circulating triglyce... 4 | 42
abnormal femur morphology 3 | 14
decreased circulating serum al... 3 | 82
decreased total body fat amoun... 3 | 207
increased neutrophil cell numb... 3 | 46
preweaning lethality, incomple... 3 | 499
short tibia 3 | 97
abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 2 | 64
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased circulating glucose ... 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased hematocrit 2 | 46
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
decreased IgG1 level 1 | 8
decreased IgG2b level 1 | 4
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased granulocyte number 1 | 6
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased vertical activity 1 | 24
mydriasis 1 | 6
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 113 | 11,493
ovarian cancer 79 | 8,520
glioblastoma 78 | 5,792
osteosarcoma 71 | 7,950
psoriasis 61 | 6,694
Astrocytoma, Pilocytic 60 | 3,081
lung cancer 60 | 4,740
Breast cancer 58 | 3,578
Kidney cancer 57 | 2,613
ependymoma 56 | 4,679
medulloblastoma, large-cell 55 | 6,241
Cancer 54 | 2,499
atypical teratoid / rhabdoid tumor 53 | 5,112
adult high grade glioma 48 | 3,801
invasive ductal carcinoma 46 | 2,951
pancreatic cancer 46 | 2,398
non-small cell lung cancer 45 | 2,890
malignant mesothelioma 40 | 3,232
interstitial cystitis 39 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,989
ulcerative colitis 37 | 1,819
lung adenocarcinoma 36 | 2,716
lung carcinoma 35 | 2,843
Autosomal recessive predisposition 33 | 1,442
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
oligodendroglioma 33 | 2,850
pituitary cancer 32 | 1,972
cystic fibrosis 31 | 1,696
group 3 medulloblastoma 31 | 4,104
primitive neuroectodermal tumor 31 | 3,035
subependymal giant cell astrocytoma 29 | 2,287
Short stature 28 | 531
ductal carcinoma in situ 28 | 1,745
Duchenne muscular dystrophy 27 | 601
astrocytic glioma 27 | 2,597
group 4 medulloblastoma 27 | 1,855
primary pancreatic ductal adenocarcinoma 27 | 1,109
tuberculosis 27 | 2,010
juvenile dermatomyositis 25 | 1,187
gastric carcinoma 24 | 807
Liver Cirrhosis, Experimental 23 | 769
breast carcinoma 23 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
diabetes mellitus 22 | 1,728
nasopharyngeal carcinoma 22 | 1,058
Joint hyperflexibility 21 | 78
Melanoma 21 | 711
adrenocortical carcinoma 21 | 1,428
Acquired scoliosis 20 | 281
Curvature of spine 20 | 282
Hypoplastic mandible condyle 20 | 275
Mandibular hypoplasia 20 | 275
Micrognathism 20 | 275
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 510
colon cancer 20 | 1,478
cutaneous lupus erythematosus 20 | 1,057
Liver cancer 19 | 604
Muscle hypotonia 19 | 571
Myopia 19 | 176
Pick disease 19 | 1,894
Intellectual disability 18 | 1,016
Skin cancer 18 | 469
Orbital separation excessive 17 | 244
Schizophrenia 17 | 1,160
pediatric high grade glioma 17 | 1,064
Kidney disease 16 | 430
dermatomyositis 16 | 966
limb girdle muscular dystrophy 2A 16 | 213
urothelial carcinoma 16 | 318
Becker muscular dystrophy 15 | 191
Degenerative polyarthritis 15 | 115
Dull intelligence 15 | 645
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
Rheumatoid arthritis 15 | 1,191
astrocytoma 15 | 1,146
esophageal adenocarcinoma 15 | 737
Byzanthine arch palate 14 | 194
Down syndrome 14 | 499
Osteoarthritis 14 | 184
Pectus excavatum 14 | 100
Sensorineural Hearing Loss (disorder) 14 | 284
Congenital Epicanthus 13 | 177
Congenital pectus carinatum 13 | 52
Cryptorchidism 13 | 296
Decreased projection of midface 13 | 105
Hypotrophic midface 13 | 105
Midface retrusion 13 | 105
Short neck 13 | 140
Small midface 13 | 105
Vascular disease 13 | 319
acute quadriplegic myopathy 13 | 1,158
interstitial lung disease 13 | 298
primary Sjogren syndrome 13 | 735
Cataract 12 | 297
Delayed bone age 12 | 136
Strabismus 12 | 270

Tissue

Endocrine System 122 | 18,159
Digestive Tract 121 | 17,369
Female tissues 121 | 17,400
Liver and Pancreas 121 | 16,750
Male tissues 121 | 17,142
Nervous System 121 | 16,725
Skin and soft tissues 121 | 17,230
Blood and immune system 120 | 16,909
Urinary Tract 120 | 16,678
Cardiovascular System 118 | 15,192
Respiratory system 118 | 16,393

Target Family

Non-IDG 105 | 12,091
Enzyme 9 | 4,145
Kinase 9 | 634

PathwayCommons: inoh Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability