Development Level

Tbio 9,209 | 11,651
Tdark 3,327 | 6,593
Tchem 1,122 | 1,388
Tclin 412 | 612

Collection

Kinase: IDG Consortium (Target... 103 | 125
Ion Channel: IDG Consortium (T... 45 | 99
GPCR: IDG Consortium (Targets) 37 | 126
Kinase: IDG Consortium (Comple... 32 | 37
GPCR: IDG Consortium (Complete... 14 | 25

IMPC Phenotype

preweaning lethality, complete... 915 | 979
preweaning lethality, incomple... 429 | 499
embryonic lethality prior to t... 263 | 278
abnormal behavior 258 | 298
embryonic lethality prior to o... 231 | 239
abnormal embryo size 203 | 220
decreased total body fat amoun... 179 | 207
enlarged heart 166 | 210
abnormal bone structure 154 | 187
decreased vertical activity 151 | 208
increased lean body mass 149 | 172
decreased body weight 144 | 161
abnormal heart morphology 126 | 162
decreased bone mineral content 125 | 151
hyperactivity 119 | 148
decreased lean body mass 111 | 135
hypoactivity 110 | 132
decreased circulating glucose ... 107 | 126
decreased bone mineral density 106 | 126
increased total body fat amoun... 105 | 134
increased circulating alkaline... 104 | 122
embryonic growth retardation 98 | 106
increased startle reflex 95 | 112
increased bone mineral content 93 | 108
decreased grip strength 91 | 116
male infertility 90 | 123
decreased body length 88 | 101
decreased circulating choleste... 85 | 93
abnormal seminal vesicle morph... 84 | 114
increased or absent threshold ... 83 | 101
short tibia 83 | 97
cataract 82 | 92
increased mean corpuscular hem... 82 | 96
increased mean corpuscular vol... 80 | 92
prenatal lethality prior to he... 79 | 87
decreased circulating serum al... 76 | 82
abnormal lens morphology 73 | 81
decreased prepulse inhibition 69 | 82
decreased lymphocyte cell numb... 67 | 83
increased bone mineral density 67 | 72
decreased mean corpuscular vol... 66 | 79
decreased circulating triglyce... 65 | 79
decreased startle reflex 65 | 75
improved glucose tolerance 65 | 79
increased circulating HDL chol... 64 | 80
increased fasted circulating g... 64 | 76
decreased circulating HDL chol... 63 | 68
abnormal retina morphology 62 | 71
abnormal eye morphology 61 | 68
decreased leukocyte cell numbe... 60 | 73
abnormal sleep behavior 58 | 70
decreased circulating insulin ... 58 | 76
impaired glucose tolerance 58 | 75
abnormal gait 56 | 69
small superior vagus ganglion 56 | 74
abnormal behavioral response t... 55 | 66
decreased fasted circulating g... 55 | 65
decreased hemoglobin content 55 | 68
abnormal coat-hair pigmentatio... 54 | 64
decreased erythrocyte cell num... 54 | 62
increased circulating choleste... 54 | 66
increased circulating sodium l... 54 | 71
edema 53 | 59
increased heart weight 52 | 62
decreased caudal vertebrae num... 50 | 53
small testis 50 | 58
abnormal kidney morphology 49 | 65
increased monocyte cell number 48 | 63
thrombocytopenia 48 | 56
abnormal spleen morphology 47 | 55
decreased circulating total pr... 46 | 49
abnormal neural tube closure 45 | 46
abnormal skin morphology 43 | 50
decreased blood urea nitrogen ... 43 | 51
decreased mean corpuscular hem... 43 | 50
decreased circulating alanine ... 42 | 47
female infertility 42 | 60
decreased circulating alkaline... 41 | 46
increased blood urea nitrogen ... 41 | 48
hydrometra 40 | 53
decreased hematocrit 39 | 46
increased hematocrit 39 | 46
increased neutrophil cell numb... 39 | 46
abnormal testis morphology 37 | 43
decreased circulating LDL chol... 37 | 38
increased leukocyte cell numbe... 36 | 47
increased mean platelet volume 36 | 45
abnormal bone mineralization 35 | 38
abnormal cranium morphology 35 | 36
decreased red blood cell distr... 35 | 41
enlarged spleen 35 | 41
limb grasping 35 | 41
tremors 35 | 39
increased hemoglobin content 34 | 45
increased circulating triglyce... 33 | 42
increased circulating chloride... 32 | 41
increased circulating creatini... 32 | 38
increased grip strength 32 | 41
pallor 32 | 34
increased erythrocyte cell num... 31 | 39

Disease

Carcinoma 8,611 | 11,493
ovarian cancer 7,667 | 8,520
osteosarcoma 6,864 | 7,950
medulloblastoma, large-cell 5,245 | 6,241
glioblastoma 5,007 | 5,792
psoriasis 4,981 | 6,694
atypical teratoid / rhabdoid tumor 4,340 | 5,112
lung cancer 4,166 | 4,740
ependymoma 3,929 | 4,679
group 3 medulloblastoma 3,456 | 4,104
adult high grade glioma 3,119 | 3,801
Breast cancer 3,061 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,039 | 3,291
malignant mesothelioma 2,875 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 2,795 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2,769 | 2,989
invasive ductal carcinoma 2,672 | 2,951
Astrocytoma, Pilocytic 2,568 | 3,081
primitive neuroectodermal tumor 2,534 | 3,035
non-small cell lung cancer 2,493 | 2,890
lung carcinoma 2,441 | 2,843
oligodendroglioma 2,427 | 2,850
lung adenocarcinoma 2,301 | 2,716
astrocytic glioma 2,231 | 2,597
pancreatic cancer 2,115 | 2,398
subependymal giant cell astrocytoma 2,044 | 2,287
Kidney cancer 2,002 | 2,613
Cancer 1,992 | 2,499
interstitial cystitis 1,931 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 1,818 | 1,962
tuberculosis 1,773 | 2,010
Pick disease 1,713 | 1,894
pituitary cancer 1,671 | 1,972
group 4 medulloblastoma 1,655 | 1,855
ulcerative colitis 1,587 | 1,819
ductal carcinoma in situ 1,535 | 1,745
breast carcinoma 1,447 | 1,638
cystic fibrosis 1,443 | 1,696
Multiple myeloma 1,295 | 1,332
colon cancer 1,278 | 1,478
adrenocortical carcinoma 1,275 | 1,428
diabetes mellitus 1,250 | 1,728
Autosomal recessive predisposition 1,150 | 1,442
juvenile dermatomyositis 1,142 | 1,187
acute quadriplegic myopathy 1,097 | 1,158
primary pancreatic ductal adenocarcinoma 1,082 | 1,109
astrocytoma 1,069 | 1,146
Rheumatoid arthritis 1,006 | 1,191
spina bifida 963 | 1,074
pediatric high grade glioma 947 | 1,064
dermatomyositis 906 | 966
cutaneous lupus erythematosus 866 | 1,057
Intellectual disability 858 | 1,016
Schizophrenia 843 | 1,160
nasopharyngeal carcinoma 829 | 1,058
active Crohn's disease 811 | 922
gastric carcinoma 749 | 807
non primary Sjogren syndrome sicca 749 | 891
acute myeloid leukemia 743 | 783
Waldenstrons macroglobulinemia 741 | 765
Atopic dermatitis 711 | 952
Liver Cirrhosis, Experimental 682 | 769
active ulcerative colitis 666 | 764
Epilepsy 645 | 792
primary Sjogren syndrome 639 | 735
esophageal adenocarcinoma 632 | 737
aldosterone-producing adenoma 628 | 665
progressive supranuclear palsy 619 | 676
medulloblastoma 616 | 720
Duchenne muscular dystrophy 563 | 601
Alzheimer's disease 550 | 658
Dull intelligence 544 | 645
Low intelligence 544 | 645
Mental Retardation 544 | 645
Mental deficiency 544 | 645
Poor school performance 544 | 645
Cognitive delay 541 | 608
Global developmental delay 541 | 608
Mental and motor retardation 541 | 608
Obesity 523 | 678
hepatocellular carcinoma 513 | 547
Muscle hypotonia 509 | 571
pancreatic carcinoma 505 | 562
Seizures 501 | 596
fibroadenoma 496 | 559
autosomal dominant Emery-Dreifuss muscular dystrophy 488 | 510
Bipolar Disorder 481 | 666
Down syndrome 460 | 499
Short stature 443 | 531
Melanoma 437 | 711
Prostatic Neoplasms 431 | 495
gastric cancer 429 | 459
chronic rhinosinusitis 424 | 512
Endometriosis 418 | 540
Liver cancer 415 | 604
mucosa-associated lymphoid tissue lymphoma 409 | 484
Amyotrophic lateral sclerosis 407 | 451
posterior fossa group A ependymoma 405 | 468
sonic hedgehog group medulloblastoma 404 | 467
tuberculosis and treatment for 6 months 401 | 409

Tissue

Liver and Pancreas 14,070 | 16,750
Endocrine System 14,058 | 18,159
Digestive Tract 14,038 | 17,369
Female tissues 14,013 | 17,400
Skin and soft tissues 13,996 | 17,230
Male tissues 13,975 | 17,142
Urinary Tract 13,931 | 16,678
Blood and immune system 13,923 | 16,909
Nervous System 13,888 | 16,725
Respiratory system 13,877 | 16,393
Cardiovascular System 13,531 | 15,192

Target Family

Non-IDG 8,124 | 12,091
Enzyme 3,409 | 4,145
Transcription Factor 1,027 | 1,400
Kinase 552 | 634
Transporter 326 | 473
Epigenetic 219 | 242
GPCR 174 | 408
Ion Channel 163 | 344
Nuclear Receptor 41 | 48
TF/Epigenetic 31 | 38
oGPCR 4 | 421

HPA RNA Tissue

pancreas 14,070 | 14,070
testis 17,936 | 17,936
cerebral cortex 16,630 | 16,630
prostate 16,460 | 16,460
endometrium 16,349 | 16,349
gallbladder 16,333 | 16,333
lung 16,312 | 16,312
appendix 16,247 | 16,247
fallopian tube 16,245 | 16,245
skin 16,206 | 16,206
small intestine 16,154 | 16,154
stomach 16,099 | 16,099
breast 16,063 | 16,063
duodenum 15,975 | 15,975
spleen 15,972 | 15,972
adrenal gland 15,963 | 15,963
colon 15,959 | 15,959
thyroid gland 15,959 | 15,959
placenta 15,937 | 15,937
seminal vesicle 15,918 | 15,918
kidney 15,917 | 15,917
esophagus 15,898 | 15,898
cervix, uterine 15,871 | 15,871
epididymis 15,863 | 15,863
smooth muscle 15,857 | 15,857
adipose tissue 15,837 | 15,837
lymph node 15,833 | 15,833
urinary bladder 15,814 | 15,814
rectum 15,705 | 15,705
ovary 15,408 | 15,408
tonsil 15,400 | 15,400
salivary gland 14,981 | 14,981
heart muscle 14,972 | 14,972
parathyroid gland 14,769 | 14,769
liver 14,587 | 14,587
bone marrow 14,571 | 14,571
skeletal muscle 14,011 | 14,011

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability