Development Level

Tbio 627 | 11,651
Tchem 283 | 1,388
Tclin 123 | 612
Tdark 12 | 6,593

IMPC Phenotype

preweaning lethality, complete... 58 | 979
preweaning lethality, incomple... 36 | 499
embryonic lethality prior to t... 25 | 278
decreased vertical activity 22 | 208
abnormal behavior 19 | 298
decreased total body fat amoun... 19 | 207
embryonic lethality prior to o... 19 | 239
enlarged heart 19 | 210
increased total body fat amoun... 15 | 134
abnormal heart morphology 14 | 162
increased circulating choleste... 14 | 66
increased lean body mass 14 | 172
increased circulating HDL chol... 13 | 80
decreased circulating choleste... 12 | 93
hypoactivity 12 | 132
increased startle reflex 12 | 112
abnormal embryo size 11 | 220
abnormal seminal vesicle morph... 11 | 114
cataract 11 | 92
decreased body weight 11 | 161
hyperactivity 11 | 148
increased circulating alkaline... 11 | 122
abnormal lens morphology 10 | 81
decreased bone mineral content 10 | 151
decreased bone mineral density 10 | 126
decreased circulating HDL chol... 10 | 68
decreased circulating glucose ... 10 | 126
decreased mean corpuscular vol... 10 | 79
increased mean corpuscular vol... 10 | 92
increased mean corpuscular hem... 9 | 96
abnormal bone structure 8 | 187
decreased circulating triglyce... 8 | 79
improved glucose tolerance 8 | 79
abnormal bone mineralization 7 | 38
decreased erythrocyte cell num... 7 | 62
decreased lean body mass 7 | 135
decreased neutrophil cell numb... 7 | 42
increased bone mineral content 7 | 108
short tibia 7 | 97
small testis 7 | 58
abnormal gait 6 | 69
abnormal retina morphology 6 | 71
abnormal sleep behavior 6 | 70
abnormal testis morphology 6 | 43
decreased circulating LDL chol... 6 | 38
decreased circulating aspartat... 6 | 34
decreased circulating creatini... 6 | 39
decreased circulating insulin ... 6 | 76
decreased lymphocyte cell numb... 6 | 83
increased circulating triglyce... 6 | 42
increased lymphocyte cell numb... 6 | 32
increased monocyte cell number 6 | 63
male infertility 6 | 123
prolonged ST segment 6 | 36
small superior vagus ganglion 6 | 74
decreased body length 5 | 101
decreased grip strength 5 | 116
decreased heart weight 5 | 27
decreased hemoglobin content 5 | 68
decreased lactate dehydrogenas... 5 | 16
decreased prepulse inhibition 5 | 82
embryonic growth retardation 5 | 106
increased circulating bilirubi... 5 | 16
increased circulating creatini... 5 | 38
increased circulating iron lev... 5 | 30
limb grasping 5 | 41
prolonged QT interval 5 | 38
thrombocytopenia 5 | 56
abnormal epididymis morphology 4 | 42
abnormal kidney morphology 4 | 65
abnormal lung morphology 4 | 26
abnormal vibrissa morphology 4 | 25
decreased circulating alanine ... 4 | 47
decreased circulating alkaline... 4 | 46
decreased circulating bilirubi... 4 | 19
decreased circulating calcium ... 4 | 36
decreased circulating iron lev... 4 | 32
decreased circulating serum al... 4 | 82
decreased mean corpuscular hem... 4 | 50
decreased red blood cell distr... 4 | 41
hydrometra 4 | 53
impaired righting response 4 | 26
increased blood urea nitrogen ... 4 | 48
increased body length 4 | 32
increased circulating alanine ... 4 | 13
increased circulating serum al... 4 | 22
increased circulating sodium l... 4 | 71
increased circulating total pr... 4 | 28
increased fasted circulating g... 4 | 76
increased heart weight 4 | 62
increased hemoglobin content 4 | 45
increased leukocyte cell numbe... 4 | 47
increased neutrophil cell numb... 4 | 46
increased or absent threshold ... 4 | 101
abnormal coat-hair pigmentatio... 3 | 64
abnormal locomotor behavior 3 | 24
cardiovascular system phenotyp... 3 | 36
decreased fasted circulating g... 3 | 65
decreased spleen weight 3 | 10
decreased startle reflex 3 | 75

Disease

Carcinoma 681 | 11,493
Cancer 639 | 2,499
ovarian cancer 549 | 8,520
psoriasis 529 | 6,694
osteosarcoma 450 | 7,950
lung cancer 435 | 4,740
glioblastoma 392 | 5,792
diabetes mellitus 369 | 1,728
medulloblastoma, large-cell 350 | 6,241
malignant mesothelioma 316 | 3,232
Breast cancer 288 | 3,578
atypical teratoid / rhabdoid tumor 287 | 5,112
pancreatic ductal adenocarcinoma liver metastasis 287 | 1,962
intraductal papillary-mucinous neoplasm (IPMN) 282 | 3,291
ependymoma 280 | 4,679
lung carcinoma 277 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 270 | 2,955
invasive ductal carcinoma 265 | 2,951
Obesity 255 | 678
intraductal papillary-mucinous carcinoma (IPMC) 255 | 2,989
lung adenocarcinoma 255 | 2,716
non-small cell lung cancer 254 | 2,890
pancreatic cancer 250 | 2,398
Autosomal recessive predisposition 224 | 1,442
adult high grade glioma 219 | 3,801
interstitial cystitis 216 | 2,312
group 3 medulloblastoma 213 | 4,104
tuberculosis 212 | 2,010
Astrocytoma, Pilocytic 211 | 3,081
ulcerative colitis 202 | 1,819
Schizophrenia 197 | 1,160
Kidney disease 193 | 430
Liver Cirrhosis, Experimental 184 | 769
Liver disease 184 | 237
breast carcinoma 183 | 1,638
ductal carcinoma in situ 178 | 1,745
Hypertension 176 | 396
pituitary cancer 170 | 1,972
Atherosclerosis 167 | 291
primitive neuroectodermal tumor 165 | 3,035
Vascular disease 164 | 319
cystic fibrosis 162 | 1,696
oligodendroglioma 158 | 2,850
subependymal giant cell astrocytoma 155 | 2,287
Rheumatoid arthritis 154 | 1,191
adrenocortical carcinoma 153 | 1,428
Kidney cancer 151 | 2,613
colon cancer 150 | 1,478
Anemia 149 | 365
Prostatic Neoplasms 146 | 495
Breast Neoplasms 143 | 445
Mammary Neoplasms 142 | 425
Coronary artery disease 137 | 268
astrocytic glioma 127 | 2,597
Liver carcinoma 126 | 240
Heart disease 124 | 306
acute quadriplegic myopathy 123 | 1,158
Arthritis 122 | 290
cutaneous lupus erythematosus 122 | 1,057
Alzheimer's disease 121 | 658
Multiple myeloma 120 | 1,332
Carcinoma, Hepatocellular 119 | 228
Atopic dermatitis 117 | 952
astrocytoma 113 | 1,146
Asthma 112 | 385
Bipolar Disorder 112 | 666
Hypertensive disease 110 | 292
Cerebrovascular disease 108 | 238
group 4 medulloblastoma 108 | 1,855
Hypersensitivity reaction type II disease 106 | 253
Chemical and Drug Induced Liver Injury 105 | 195
Epilepsy 105 | 792
juvenile dermatomyositis 105 | 1,187
Depressive disorder 103 | 409
active Crohn's disease 103 | 922
Multiple Sclerosis 100 | 540
dermatomyositis 100 | 966
Hyperglycemia 98 | 137
active ulcerative colitis 97 | 764
Diarrhea 96 | 253
primary pancreatic ductal adenocarcinoma 96 | 1,109
Hepatomegaly 95 | 285
Liver Cirrhosis 95 | 181
Lung disease 93 | 142
Lung Neoplasms 92 | 232
Stomach Neoplasms 92 | 300
Seizures 91 | 596
nasopharyngeal carcinoma 91 | 1,058
Cholestasis 90 | 155
Pick disease 90 | 1,894
Endometriosis 88 | 540
Inflammatory bowel disease 88 | 151
esophageal adenocarcinoma 88 | 737
Fatty liver disease 86 | 103
Intellectual disability 84 | 1,016
Melanoma 84 | 711
gastric carcinoma 84 | 807
pediatric high grade glioma 83 | 1,064
Lipid metabolism disorder 82 | 114
Osteoporosis 81 | 363

Tissue

Digestive Tract 1,006 | 17,369
Endocrine System 1,001 | 18,159
Liver and Pancreas 998 | 16,750
Skin and soft tissues 994 | 17,230
Urinary Tract 983 | 16,678
Female tissues 981 | 17,400
Blood and immune system 970 | 16,909
Male tissues 970 | 17,142
Respiratory system 937 | 16,393
Nervous System 934 | 16,725
Cardiovascular System 857 | 15,192

Target Family

Non-IDG 429 | 12,091
Enzyme 390 | 4,145
Transcription Factor 74 | 1,400
Kinase 62 | 634
Transporter 42 | 473
Nuclear Receptor 19 | 48
GPCR 12 | 408
Epigenetic 10 | 242
Ion Channel 4 | 344
TF/Epigenetic 3 | 38

Jensen-TM Tissue

Liver 1,045 | 1,045
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability