Development Level

Tbio 23 | 11,445
Tchem 3 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased body length 2 | 101
increased leukocyte cell numbe... 2 | 47
preweaning lethality, incomple... 2 | 499
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal incisor morphology 1 | 4
abnormal radius morphology 1 | 8
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
increased blood urea nitrogen ... 1 | 48
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 25 | 11,493
ovarian cancer 18 | 8,520
lung carcinoma 17 | 2,843
atypical teratoid / rhabdoid tumor 16 | 5,112
glioblastoma 16 | 5,792
osteosarcoma 16 | 7,950
psoriasis 16 | 6,694
ependymoma 15 | 4,679
malignant mesothelioma 14 | 3,232
pancreatic cancer 14 | 2,398
lung cancer 13 | 4,740
medulloblastoma, large-cell 13 | 6,241
Astrocytoma, Pilocytic 12 | 3,081
Breast cancer 12 | 3,578
Cancer 12 | 2,499
lung adenocarcinoma 12 | 2,716
non-small cell lung cancer 12 | 2,890
primary pancreatic ductal adenocarcinoma 12 | 1,109
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
invasive ductal carcinoma 11 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Autosomal recessive predisposition 9 | 1,442
adult high grade glioma 9 | 3,801
colon cancer 9 | 1,478
ductal carcinoma in situ 9 | 1,745
group 3 medulloblastoma 9 | 4,104
Atopic dermatitis 8 | 952
Liver Cirrhosis, Experimental 8 | 769
Orbital separation excessive 7 | 244
Short stature 7 | 531
adrenocortical carcinoma 7 | 1,428
breast carcinoma 7 | 1,638
cutaneous lupus erythematosus 7 | 1,057
cystic fibrosis 7 | 1,696
pituitary cancer 7 | 1,972
Brachydactyly 6 | 156
Endometriosis 6 | 540
Osteoarthritis 6 | 184
Prostatic Neoplasms 6 | 495
Schizophrenia 6 | 1,160
diabetes mellitus 6 | 1,728
interstitial cystitis 6 | 2,312
Cleft Palate 5 | 271
Coronary artery disease 5 | 268
Duchenne muscular dystrophy 5 | 601
Hernia, Inguinal 5 | 89
Hypertensive disease 5 | 292
Kidney cancer 5 | 2,613
Osteoporosis 5 | 363
Pulmonary emphysema 5 | 48
oligodendroglioma 5 | 2,850
pediatric high grade glioma 5 | 1,064
Acquired metabolic disease 4 | 336
Acquired scoliosis 4 | 281
Aortic Valve Insufficiency 4 | 40
Aortic aneurysm 4 | 38
Arachnodactyly 4 | 49
Colorectal Neoplasms 4 | 243
Curvature of spine 4 | 282
Exophthalmos 4 | 112
Increase in blood pressure 4 | 119
Pectus excavatum 4 | 100
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
Retrognathia 4 | 54
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
limb girdle muscular dystrophy 2A 4 | 213
tuberculosis 4 | 2,010
Arthritis 3 | 290
Blepharoptosis 3 | 231
Breast Neoplasms 3 | 445
Byzanthine arch palate 3 | 194
Cerebrovascular accident 3 | 63
Chest Pain 3 | 38
Congenital Epicanthus 3 | 177
Cutis Laxa 3 | 39
Decreased joint mobility 3 | 53
Degenerative polyarthritis 3 | 115
Downward slant of palpebral fissure 3 | 158
Generalized elastolysis 3 | 24
Hanging skin 3 | 24
Hypotrophic malar bone 3 | 129
Joint hyperflexibility 3 | 78
Malar flattening 3 | 129
Mammary Neoplasms 3 | 425
Myopia 3 | 176
Stomach Neoplasms 3 | 300
Stroke 3 | 33
Vascular disease 3 | 319
acute quadriplegic myopathy 3 | 1,158
dermatomyositis 3 | 966
fascioscapulohumeral muscular dystrophy 3 | 100
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Blood and immune system 28 | 16,909
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 28 | 12,091
Transcription Factor 1 | 1,400

Reactome Pathway

Molecules associated with elas... 29 | 29
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Latent-transforming growth factor beta-binding protein 2 LTBP2 Tbio Non-IDG -1.22721 18.2 100
Integrin alpha-8 ITGA8 Tbio Non-IDG -1.36974 22.0 145
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Fibulin-1 FBLN1 Tbio Non-IDG -1.97380 101.1 218
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Transforming growth factor beta-3 TGFB3 Tbio Non-IDG -3.02749 1062.5 308
Fibulin-5 FBLN5 Tbio Non-IDG -2.32385 217.1 297
Latent-transforming growth factor beta-binding protein 4 LTBP4 Tbio Non-IDG -1.55113 39.1 57