Development Level

Tbio 2,497 | 11,651
Tchem 550 | 1,388
Tclin 244 | 612
Tdark 170 | 6,593

Collection

RFA-RM-18-021 40 | 328
Kinase: IDG Consortium (Target... 20 | 125
GPCR: IDG Consortium (Targets) 13 | 126
GPCR: IDG Consortium (Complete... 10 | 25
Ion Channel: IDG Consortium (T... 7 | 99
Kinase: IDG Consortium (Comple... 4 | 37

IMPC Phenotype

preweaning lethality, complete... 279 | 979
preweaning lethality, incomple... 168 | 499
abnormal behavior 89 | 298
decreased total body fat amoun... 86 | 207
abnormal bone structure 80 | 187
embryonic lethality prior to t... 72 | 278
decreased body weight 71 | 161
decreased vertical activity 71 | 208
abnormal embryo size 68 | 220
enlarged heart 68 | 210
increased lean body mass 66 | 172
decreased bone mineral content 63 | 151
decreased lean body mass 60 | 135
increased circulating alkaline... 58 | 122
increased total body fat amoun... 57 | 134
decreased leukocyte cell numbe... 56 | 73
embryonic lethality prior to o... 55 | 239
decreased bone mineral density 53 | 126
decreased circulating glucose ... 46 | 126
hypoactivity 45 | 132
decreased body length 44 | 101
increased mean corpuscular hem... 43 | 96
abnormal heart morphology 42 | 162
abnormal seminal vesicle morph... 41 | 114
increased startle reflex 41 | 112
decreased grip strength 40 | 116
male infertility 40 | 123
abnormal spleen morphology 39 | 55
increased bone mineral content 39 | 108
increased circulating HDL chol... 39 | 80
decreased circulating triglyce... 37 | 79
decreased mean corpuscular vol... 37 | 79
decreased lymphocyte cell numb... 36 | 83
increased leukocyte cell numbe... 36 | 47
cataract 35 | 92
decreased hemoglobin content 35 | 68
hyperactivity 35 | 148
increased or absent threshold ... 35 | 101
short tibia 35 | 97
increased circulating choleste... 34 | 66
increased mean corpuscular vol... 34 | 92
thrombocytopenia 34 | 56
impaired glucose tolerance 33 | 75
decreased circulating choleste... 32 | 93
abnormal retina morphology 31 | 71
decreased erythrocyte cell num... 31 | 62
increased bone mineral density 31 | 72
prenatal lethality prior to he... 31 | 87
abnormal lens morphology 30 | 81
decreased circulating serum al... 29 | 82
embryonic growth retardation 29 | 106
decreased blood urea nitrogen ... 28 | 51
enlarged spleen 28 | 41
improved glucose tolerance 28 | 79
small superior vagus ganglion 28 | 74
decreased mean corpuscular hem... 27 | 50
decreased circulating HDL chol... 26 | 68
decreased hematocrit 26 | 46
decreased prepulse inhibition 26 | 82
enlarged lymph nodes 26 | 37
decreased circulating insulin ... 25 | 76
decreased neutrophil cell numb... 25 | 42
decreased startle reflex 25 | 75
abnormal cranium morphology 24 | 36
abnormal eye morphology 24 | 68
decreased circulating total pr... 24 | 49
increased hemoglobin content 24 | 45
increased monocyte cell number 24 | 63
increased neutrophil cell numb... 24 | 46
edema 23 | 59
increased grip strength 23 | 41
increased heart weight 23 | 62
abnormal gait 21 | 69
abnormal kidney morphology 21 | 65
decreased circulating alanine ... 21 | 47
increased blood urea nitrogen ... 21 | 48
increased circulating calcium ... 21 | 34
abnormal sleep behavior 20 | 70
increased circulating sodium l... 20 | 71
increased fasted circulating g... 20 | 76
increased red blood cell distr... 20 | 34
corneal opacity 19 | 32
decreased circulating alkaline... 19 | 46
decreased fasted circulating g... 19 | 65
increased lymphocyte cell numb... 19 | 32
decreased caudal vertebrae num... 18 | 53
decreased circulating fructosa... 18 | 30
decreased circulating iron lev... 18 | 32
increased circulating iron lev... 18 | 30
increased erythrocyte cell num... 18 | 39
increased mean platelet volume 18 | 45
abnormal behavioral response t... 17 | 66
abnormal skin morphology 17 | 50
increased hematocrit 17 | 46
small testis 17 | 58
abnormal bone mineralization 16 | 38
abnormal coat-hair pigmentatio... 16 | 64
anophthalmia 16 | 33
increased circulating triglyce... 16 | 42
tremors 16 | 39

Disease

Carcinoma 2,330 | 11,493
ovarian cancer 1,882 | 8,520
osteosarcoma 1,798 | 7,950
psoriasis 1,564 | 6,694
glioblastoma 1,345 | 5,792
medulloblastoma, large-cell 1,329 | 6,241
lung cancer 1,317 | 4,740
Cancer 1,202 | 2,499
atypical teratoid / rhabdoid tumor 1,022 | 5,112
ependymoma 933 | 4,679
Breast cancer 899 | 3,578
malignant mesothelioma 898 | 3,232
non-small cell lung cancer 846 | 2,890
lung carcinoma 844 | 2,843
invasive ductal carcinoma 834 | 2,951
group 3 medulloblastoma 820 | 4,104
adult high grade glioma 816 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 816 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 768 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 761 | 2,955
lung adenocarcinoma 757 | 2,716
interstitial cystitis 756 | 2,312
Astrocytoma, Pilocytic 749 | 3,081
pancreatic cancer 714 | 2,398
tuberculosis 687 | 2,010
ulcerative colitis 653 | 1,819
Kidney cancer 605 | 2,613
oligodendroglioma 575 | 2,850
primitive neuroectodermal tumor 573 | 3,035
subependymal giant cell astrocytoma 560 | 2,287
Autosomal recessive predisposition 519 | 1,442
pituitary cancer 503 | 1,972
cystic fibrosis 502 | 1,696
diabetes mellitus 494 | 1,728
astrocytic glioma 481 | 2,597
ductal carcinoma in situ 480 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 451 | 1,962
breast carcinoma 448 | 1,638
colon cancer 433 | 1,478
cutaneous lupus erythematosus 426 | 1,057
group 4 medulloblastoma 420 | 1,855
Rheumatoid arthritis 413 | 1,191
Schizophrenia 378 | 1,160
adrenocortical carcinoma 372 | 1,428
juvenile dermatomyositis 369 | 1,187
Pick disease 347 | 1,894
primary pancreatic ductal adenocarcinoma 345 | 1,109
astrocytoma 341 | 1,146
Liver Cirrhosis, Experimental 311 | 769
primary Sjogren syndrome 309 | 735
acute quadriplegic myopathy 298 | 1,158
Multiple myeloma 297 | 1,332
Intellectual disability 277 | 1,016
Atopic dermatitis 273 | 952
dermatomyositis 270 | 966
pediatric high grade glioma 263 | 1,064
gastric carcinoma 258 | 807
nasopharyngeal carcinoma 258 | 1,058
spina bifida 257 | 1,074
Multiple Sclerosis 255 | 540
active Crohn's disease 255 | 922
Obesity 251 | 678
esophageal adenocarcinoma 239 | 737
Asthma 230 | 385
Prostatic Neoplasms 228 | 495
Kidney disease 222 | 430
Waldenstrons macroglobulinemia 222 | 765
Bipolar Disorder 220 | 666
Breast Neoplasms 220 | 445
acute myeloid leukemia 219 | 783
Melanoma 217 | 711
Mammary Neoplasms 212 | 425
Short stature 212 | 531
active ulcerative colitis 212 | 764
Anemia 210 | 365
Epilepsy 205 | 792
Duchenne muscular dystrophy 204 | 601
Dull intelligence 203 | 645
Low intelligence 203 | 645
Mental Retardation 203 | 645
Mental deficiency 203 | 645
Poor school performance 203 | 645
non primary Sjogren syndrome sicca 195 | 891
Alzheimer's disease 193 | 658
Seizures 189 | 596
Arthritis 187 | 290
Hypertension 187 | 396
Cognitive delay 186 | 608
Global developmental delay 186 | 608
Mental and motor retardation 186 | 608
mucosa-associated lymphoid tissue lymphoma 185 | 484
Endometriosis 180 | 540
Down syndrome 179 | 499
hepatocellular carcinoma 176 | 547
aldosterone-producing adenoma 174 | 665
Hypersensitivity reaction type II disease 172 | 253
Depressive disorder 170 | 409
medulloblastoma 170 | 720
Muscle hypotonia 169 | 571
Atherosclerosis 168 | 291

Tissue

Endocrine System 3,364 | 18,159
Digestive Tract 3,342 | 17,369
Female tissues 3,325 | 17,400
Skin and soft tissues 3,320 | 17,230
Liver and Pancreas 3,290 | 16,750
Blood and immune system 3,288 | 16,909
Male tissues 3,284 | 17,142
Urinary Tract 3,274 | 16,678
Respiratory system 3,245 | 16,393
Nervous System 3,221 | 16,725
Cardiovascular System 3,063 | 15,192

Target Family

Non-IDG 1,796 | 12,091
Enzyme 776 | 4,145
Transcription Factor 291 | 1,400
Kinase 229 | 634
GPCR 122 | 408
Transporter 76 | 473
Epigenetic 74 | 242
Ion Channel 58 | 344
Nuclear Receptor 28 | 48
TF/Epigenetic 11 | 38

MGI Phenotype

immune system phenotype 3,461 | 3,461
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
Tyrosine-protein phosphatase non-receptor type 5 PTPN5 Tchem Enzyme -1.85420 70.8 225
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388