Targets

Target Filters...

This is where graphics are reside..

Name	Gene	Development Level	Target Family	Log Novelty	Pubmed Score	Antibody Count
E3 ubiquitin-protein ligase Praja-2	PJA2	Tbio	Enzyme	-0.64427	2.59	159
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2	PLCB2	Tbio	Enzyme	-2.12987	136.7	95
Prostate stem cell antigen	PSCA	Tbio	Non-IDG	-2.37806	257.9	258
BTB/POZ domain-containing protein 16	BTBD16	Tbio	Non-IDG	0.14	0.32	57
Guanine nucleotide-binding protein G(i) subunit alpha-1	GNAI1	Tchem	Non-IDG	-0.58441	3.11	173
Ephrin type-A receptor 6	EPHA6	Tchem	Kinase	-1.33373	29.2	223
RING finger protein 10	RNF10	Tbio	Non-IDG	-0.78173	6.31	120
Pigment epithelium-derived factor	SERPINF1	Tbio	Non-IDG	-2.08036	127.8	351
Zinc finger BED domain-containing protein 4	ZBED4	Tdark	Transcription Factor	-0.65120	4.10	4
Transcriptional regulator ERG	ERG	Tchem	Transcription Factor	-1.18406	317.4	284

	Tbio	25 \| 10,625
	Tdark	6 \| 7,003
	Tchem	4 \| 1,890
	Tclin	1 \| 602

	abnormal spleen morphology	36 \| 36
	preweaning lethality, complete...	633 \| 633
	preweaning lethality, incomple...	260 \| 260
	abnormal behavior	226 \| 226
	decreased lean body mass	195 \| 195
	embryonic lethality prior to t...	187 \| 187
	decreased total body fat amoun...	186 \| 186
	decreased body weight	174 \| 174
	decreased bone mineral content	157 \| 157
	embryonic lethality prior to o...	148 \| 148
	abnormal bone structure	131 \| 131
	increased or absent threshold ...	128 \| 128
	decreased bone mineral density	126 \| 126
	decreased grip strength	123 \| 123
	decreased circulating glucose ...	121 \| 121
	increased circulating alkaline...	119 \| 119
	abnormal embryo size	112 \| 112
	enlarged heart	111 \| 111
	decreased body length	108 \| 108
	hyperactivity	108 \| 108
	increased lean body mass	107 \| 107
	abnormal retina morphology	100 \| 100
	increased mean corpuscular hem...	93 \| 93
	increased bone mineral content	92 \| 92
	increased mean corpuscular vol...	91 \| 91
	hypoactivity	89 \| 89
	decreased circulating choleste...	85 \| 85
	decreased circulating triglyce...	83 \| 83
	increased grip strength	83 \| 83
	short tibia	82 \| 82
	decreased circulating serum al...	79 \| 79
	decreased circulating HDL chol...	77 \| 77
	decreased circulating insulin ...	75 \| 75
	abnormal lens morphology	73 \| 73
	increased circulating sodium l...	71 \| 71
	increased fasted circulating g...	68 \| 68
	prenatal lethality prior to he...	64 \| 64
	abnormal sleep behavior	63 \| 63
	increased circulating HDL chol...	63 \| 63
	decreased lumbar vertebrae num...	62 \| 62
	increased sacral vertebrae num...	62 \| 62
	male infertility	62 \| 62
	abnormal retinal pigmentation	61 \| 61
	decreased rib number	59 \| 59
	increased total body fat amoun...	57 \| 57
	improved glucose tolerance	56 \| 56
	increased exploration in new e...	56 \| 56
	abnormal bone mineralization	55 \| 55
	abnormal coat-hair pigmentatio...	54 \| 54
	decreased leukocyte cell numbe...	54 \| 54
	decreased circulating alanine ...	53 \| 53
	decreased hemoglobin content	53 \| 53
	increased circulating choleste...	53 \| 53
	abnormal behavioral response t...	52 \| 52
	decreased prepulse inhibition	52 \| 52
	impaired glucose tolerance	52 \| 52
	increased bone mineral density	52 \| 52
	abnormal gait	51 \| 51
	abnormal heart morphology	51 \| 51
	decreased mean corpuscular vol...	50 \| 50
	decreased caudal vertebrae num...	49 \| 49
	decreased fasted circulating g...	49 \| 49
	decreased startle reflex	48 \| 48
	abnormal seminal vesicle morph...	47 \| 47
	thrombocytopenia	46 \| 46
	increased hemoglobin content	45 \| 45
	decreased heart weight	44 \| 44
	increased blood urea nitrogen ...	44 \| 44
	decreased erythrocyte cell num...	43 \| 43
	increased circulating chloride...	43 \| 43
	increased body weight	42 \| 42
	decreased circulating alkaline...	41 \| 41
	decreased circulating total pr...	41 \| 41
	decreased eosinophil cell numb...	41 \| 41
	increased rib number	41 \| 41
	decreased circulating free fat...	39 \| 39
	abnormal eye morphology	38 \| 38
	increased startle reflex	38 \| 38
	abnormal neural tube closure	37 \| 37
	decreased circulating LDL chol...	37 \| 37
	decreased neutrophil cell numb...	37 \| 37
	increased heart weight	37 \| 37
	increased leukocyte cell numbe...	37 \| 37
	small testis	37 \| 37
	increased hematocrit	36 \| 36
	cardiovascular system phenotyp...	35 \| 35
	limb grasping	35 \| 35
	decreased mean corpuscular hem...	34 \| 34
	female infertility	34 \| 34
	tremors	34 \| 34
	decreased circulating calcium ...	33 \| 33
	abnormal cranium morphology	32 \| 32
	decreased circulating chloride...	32 \| 32
	decreased threshold for audito...	32 \| 32
	increased circulating calcium ...	32 \| 32
	abnormal epididymis morphology	31 \| 31
	decreased T cell number	31 \| 31
	decreased blood urea nitrogen ...	31 \| 31
	decreased circulating fructosa...	31 \| 31
	increased circulating potassiu...	31 \| 31

	ovarian cancer	19 \| 8,491
	psoriasis	17 \| 6,685
	osteosarcoma	16 \| 7,933
	medulloblastoma, large-cell	13 \| 6,234
	glioblastoma	11 \| 5,572
	lung cancer	11 \| 4,473
	atypical teratoid / rhabdoid tumor	9 \| 4,369
	subependymal giant cell astrocytoma	9 \| 2,287
	Breast cancer	8 \| 3,098
	ductal carcinoma in situ	8 \| 1,745
	invasive ductal carcinoma	8 \| 2,950
	malignant mesothelioma	8 \| 3,163
	breast carcinoma	7 \| 1,614
	interstitial cystitis	7 \| 2,299
	intraductal papillary-mucinous neoplasm (IPMN)	7 \| 3,289
	cystic fibrosis	6 \| 1,670
	group 3 medulloblastoma	6 \| 2,254
	non-small cell lung cancer	6 \| 2,798
	pituitary cancer	6 \| 1,972
	primitive neuroectodermal tumor	6 \| 3,031
	Prostatic Neoplasms	5 \| 471
	intraductal papillary-mucinous adenoma (IPMA)	5 \| 2,956
	lung adenocarcinoma	5 \| 2,714
	lung carcinoma	5 \| 2,844
	oligodendroglioma	5 \| 2,849
	pancreatic cancer	5 \| 2,300
	posterior fossa group B ependymoma	5 \| 1,530
	Cancer	4 \| 2,346
	Pick disease	4 \| 1,893
	astrocytic glioma	4 \| 2,241
	astrocytoma	4 \| 1,493
	intraductal papillary-mucinous carcinoma (IPMC)	4 \| 2,988
	medulloblastoma	4 \| 1,524
	primary pancreatic ductal adenocarcinoma	4 \| 1,271
	spina bifida	4 \| 1,064
	Rheumatoid Arthritis	3 \| 1,170
	Stomach Neoplasms	3 \| 282
	adrenocortical carcinoma	3 \| 1,427
	adult high grade glioma	3 \| 2,148
	cutaneous lupus erythematosus	3 \| 1,056
	fibroadenoma	3 \| 557
	interstitial lung disease	3 \| 292
	juvenile dermatomyositis	3 \| 1,189
	pediatric high grade glioma	3 \| 2,712
	pilocytic astrocytoma	3 \| 3,086
	ulcerative colitis	3 \| 2,087
	Bladder Neoplasm	2 \| 109
	IGA Glomerulonephritis	2 \| 454
	Intellectual disability	2 \| 573
	Joubert syndrome	2 \| 62
	Meckel syndrome	2 \| 48
	Schizophrenia	2 \| 503
	active Crohn's disease	2 \| 918
	acute myeloid leukemia	2 \| 785
	acute quadriplegic myopathy	2 \| 1,157
	aldosterone-producing adenoma	2 \| 664
	atypical teratoid/rhabdoid tumor	2 \| 1,095
	chronic lymphocytic leukemia	2 \| 244
	colon cancer	2 \| 1,475
	ependymoma	2 \| 2,514
	gastric cancer	2 \| 436
	gastric carcinoma	2 \| 832
	glioblastoma multiforme	2 \| 347
	group 4 medulloblastoma	2 \| 1,875
	hepatocellular carcinoma	2 \| 550
	hereditary spastic paraplegia	2 \| 313
	pancreatic carcinoma	2 \| 567
	posterior fossa group A ependymoma	2 \| 1,511
	progressive supranuclear palsy	2 \| 674
	sonic hedgehog group medulloblastoma	2 \| 1,482
	Adenoid Cystic Carcinoma	1 \| 99
	Amyotrophic lateral sclerosis type 3	1 \| 15
	Anemia	1 \| 252
	Arsenic Poisoning	1 \| 59
	Autistic Disorder	1 \| 320
	Carcinoma, Transitional Cell	1 \| 31
	Cerebral palsy	1 \| 28
	Colonic Neoplasms	1 \| 126
	Dermatologic disorders	1 \| 65
	Fanconi's anemia	1 \| 50
	Gaucher disease type 1	1 \| 171
	Gout	1 \| 93
	HIV Infections	1 \| 99
	Heart conduction disease	1 \| 65
	Infertility	1 \| 163
	Kidney Diseases	1 \| 86
	Leukopenia	1 \| 42
	Liver neoplasms	1 \| 108
	Lung Neoplasms	1 \| 171
	Malignant neoplasm of urinary bladder	1 \| 16
	Mammary Neoplasms	1 \| 410
	Microcephaly	1 \| 149
	Muscle Weakness	1 \| 92
	Neurodegenerative disease	1 \| 383
	Quadriplegia	1 \| 14
	Seckel syndrome	1 \| 35
	Squamous cell carcinoma of esophagus	1 \| 82
	Thrombocytopenia	1 \| 105
	Urinary bladder cancer	1 \| 34
	sarcoidosis	1 \| 368

	Blood and immune system	36 \| 17,994
	Female tissues	36 \| 18,646
	Male tissues	36 \| 17,968
	Nervous System	36 \| 18,560
	Digestive Tract	35 \| 18,472
	Endocrine System	35 \| 18,511
	Liver and Pancreas	35 \| 18,135
	Urinary Tract	35 \| 18,443
	Cardiovascular System	34 \| 17,957
	Skin and soft tissues	34 \| 18,114
	Respiratory system	33 \| 17,483

	Non-IDG	20 \| 11,969
	Enzyme	9 \| 4,146
	Kinase	4 \| 634
	Transcription Factor	2 \| 1,400
	Ion Channel	1 \| 341

Development Level

Collection

IMPC Phenotype

Disease

Tissue

Target Family

Drug Target Ontology

Target Development Level

Target Family

PANTHER Protein Ontology

Ligand

GTEx Tissue

HPA RNA Tissue

HPA Protein Tissue

HPM Tissue

JAX/MGI Phenotype

OMIM Phenotype

GWAS Trait

GO Component

UniProt Keywords

Grant Funding IC

Grant Activity

Data Source