Development Level

Tchem 58 | 1,885
Tbio 43 | 11,178
Tclin 34 | 612
Tdark 4 | 6,569

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 9 | 499
abnormal behavior 4 | 298
decreased vertical activity 4 | 208
decreased blood urea nitrogen ... 3 | 51
decreased circulating LDL chol... 3 | 38
decreased grip strength 3 | 116
decreased total body fat amoun... 3 | 207
increased circulating choleste... 3 | 66
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 172
increased startle reflex 3 | 112
limb grasping 3 | 41
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
absent startle reflex 2 | 24
decreased basophil cell number 2 | 16
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating insulin ... 2 | 76
decreased circulating sodium l... 2 | 22
decreased lean body mass 2 | 135
decreased prepulse inhibition 2 | 82
edema 2 | 59
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased circulating HDL chol... 2 | 80
increased circulating LDL chol... 2 | 13
increased circulating chloride... 2 | 41
increased mean platelet volume 2 | 45
increased total body fat amoun... 2 | 134
tremors 2 | 39
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
cyanosis 1 | 7
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
enlarged epididymis 1 | 31
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
male infertility 1 | 123
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
respiratory system phenotype 1 | 2
shortened QRS complex duration 1 | 1
small testis 1 | 58

Disease

Toxic encephalopathy 139 | 139
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 135 | 18,159
Female tissues 132 | 17,400
Nervous System 131 | 16,725
Digestive Tract 130 | 17,369
Male tissues 130 | 17,142
Skin and soft tissues 130 | 17,230
Blood and immune system 128 | 16,909
Liver and Pancreas 128 | 16,750
Urinary Tract 127 | 16,678
Respiratory system 123 | 16,393
Cardiovascular System 113 | 15,192

Target Family

Non-IDG 53 | 12,091
Enzyme 45 | 4,145
Kinase 11 | 634
Ion Channel 9 | 344
GPCR 7 | 408
Transporter 7 | 473
Transcription Factor 6 | 1,400
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Heat shock 70 kDa protein 4 HSPA4 Tbio Non-IDG -3.92672 8635.1 432
BDNF/NT-3 growth factors receptor NTRK2 Tchem Kinase -3.14477 1170.3 947
Allograft inflammatory factor 1 AIF1 Tbio Non-IDG -3.07876 1105.3 601
2,4-dienoyl-CoA reductase, mitochondrial DECR1 Tbio Enzyme -4.22091 15887.9 151
Excitatory amino acid transporter 1 SLC1A3 Tchem Transporter -2.76402 569.7 221
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.65839 4688.0 397
5-hydroxytryptamine receptor 7 HTR7 Tclin GPCR -4.15964 13643.7 259
Excitatory amino acid transporter 2 SLC1A2 Tchem Transporter -2.96237 939.6 187
Inter-alpha-trypsin inhibitor heavy chain H4 ITIH4 Tbio Non-IDG -3.32943 2206.3 282
Major prion protein PRNP Tchem Non-IDG -3.45326 5611.1 484