Development Level

Tbio 54 | 11,178
Tchem 35 | 1,885
Tclin 16 | 612
Tdark 6 | 6,569

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased vertical activity 4 | 208
increased circulating choleste... 4 | 66
abnormal bone structure 2 | 187
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
abnormal tooth morphology 2 | 24
cataract 2 | 92
decreased body weight 2 | 161
decreased circulating LDL chol... 2 | 38
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating free fat... 2 | 20
increased circulating triglyce... 2 | 42
increased startle reflex 2 | 112
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin condition 1 | 6
abnormal testis morphology 1 | 43
absent optic nerve 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating lipase l... 1 | 3
decreased circulating sodium l... 1 | 22
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
hypoactivity 1 | 132
increased circulating LDL chol... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating iron lev... 1 | 30
increased circulating unsatura... 1 | 1
increased heart rate 1 | 23
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
male infertility 1 | 123
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small testis 1 | 58
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Lipid metabolism disorder 111 | 111
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 109 | 18,159
Liver and Pancreas 109 | 16,750
Digestive Tract 107 | 17,369
Female tissues 106 | 17,400
Skin and soft tissues 105 | 17,230
Urinary Tract 104 | 16,678
Male tissues 102 | 17,142
Nervous System 100 | 16,725
Blood and immune system 98 | 16,909
Respiratory system 97 | 16,393
Cardiovascular System 91 | 15,192

Target Family

Non-IDG 58 | 12,091
Enzyme 34 | 4,145
Transcription Factor 5 | 1,400
Transporter 5 | 473
Nuclear Receptor 4 | 48
GPCR 2 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plasminogen-like protein A PLGLA Tdark Non-IDG -3.96245 15129.1 0
T-cell immunoglobulin and mucin domain-containing protein 4 TIMD4 Tbio Non-IDG -1.91309 95.7 291
Hydroxycarboxylic acid receptor 2 HCAR2 Tclin GPCR -2.07664 126.0 126
Nitric oxide synthase, endothelial NOS3 Tchem Enzyme -3.96497 9525.3 1195
Phosphatidylcholine-sterol acyltransferase LCAT Tchem Enzyme -2.52851 336.6 270
Hepatocyte nuclear factor 1-alpha HNF1A Tbio Transcription Factor -2.87439 680.9 0
Fibroblast growth factor 21 FGF21 Tbio Non-IDG -2.81854 777.4 443
ATP-binding cassette sub-family G member 1 ABCG1 Tbio Transporter -2.52701 319.9 260
Isobutyryl-CoA dehydrogenase, mitochondrial ACAD8 Tbio Enzyme -1.14784 13.9 150
Apolipoprotein B-100 APOB Tchem Non-IDG -4.00022 10024.1 856