Development Level

Tbio 21 | 11,651
Tchem 4 | 1,388
Tclin 1 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 4 | 278
decreased body weight 2 | 161
increased startle reflex 2 | 112
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal brain morphology 1 | 13
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal iris morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spleen morphology 1 | 55
cataract 1 | 92
cleft palate 1 | 8
decreased circulating glucose ... 1 | 126
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased spleen weight 1 | 10
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 25 | 11,493
osteosarcoma 14 | 7,950
psoriasis 14 | 6,694
ovarian cancer 13 | 8,520
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
interstitial cystitis 10 | 2,312
Kidney cancer 9 | 2,613
invasive ductal carcinoma 9 | 2,951
Autosomal recessive predisposition 8 | 1,442
Breast cancer 8 | 3,578
Cancer 8 | 2,499
Polydactyly 8 | 107
glioblastoma 8 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung cancer 8 | 4,740
malignant mesothelioma 8 | 3,232
Gastrointestinal Stromal Tumors 7 | 48
lung adenocarcinoma 7 | 2,716
medulloblastoma, large-cell 7 | 6,241
pituitary cancer 7 | 1,972
Cleft Palate 6 | 271
Intellectual disability 6 | 1,016
astrocytic glioma 6 | 2,597
chronic rhinosinusitis 6 | 512
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
medulloblastoma 6 | 720
pancreatic cancer 6 | 2,398
Astrocytoma, Pilocytic 5 | 3,081
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Bilateral fifth finger clinodactyly 4 | 110
Brachydactyly 4 | 156
Curvature of little finger 4 | 110
Narrow thorax 4 | 53
Short stature 4 | 531
Ulnar polydactyly of fingers 4 | 47
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Acquired scoliosis 3 | 281
Agenesis of corpus callosum 3 | 83
Asphyxiating thoracic dystrophy 3 | 44
Atrial Septal Defects 3 | 85
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Ciliopathy 3 | 71
Cleft Lip 3 | 141
Conductive hearing loss 3 | 123
Congenital hypoplasia of penis 3 | 176
Craniosynostosis 3 | 74
Cryptorchidism 3 | 296
Curvature of spine 3 | 282
Eye Abnormalities 3 | 35
Hepatomegaly 3 | 285
Holoprosencephaly 3 | 56
Hypoplastic feet 3 | 66
Joubert syndrome 3 | 66
Liver carcinoma 3 | 240
Mammary Neoplasms 3 | 425
Micromelia 3 | 58
Micronychia (disorder) 3 | 24
Nevoid basal cell carcinoma syndrome 3 | 16
Orbital separation excessive 3 | 244
Penile hypospadias 3 | 106
Polydactyly of toes 3 | 12
Short distal phalanges 3 | 50
Short hands 3 | 50
Short ribs 3 | 30
Situs Inversus 3 | 65
Splenomegaly 3 | 190
Syndactyly 3 | 88
Syndactyly of fingers 3 | 48
Syndactyly of the toes 3 | 45
Synostosis 3 | 15
atypical teratoid/rhabdoid tumor 3 | 357
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
sonic hedgehog group medulloblastoma 3 | 467
subependymal giant cell astrocytoma 3 | 2,287
Anteverted nostril 2 | 191
Broad flat nasal bridge 2 | 236
Concave bridge of nose 2 | 195
Depressed nasal root/bridge 2 | 195
Nasal bridge wide 2 | 236
Pectus excavatum 2 | 100
active Crohn's disease 2 | 922

Tissue

Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678
Blood and immune system 24 | 16,909
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 16 | 12,091
Transcription Factor 4 | 1,400
Enzyme 3 | 4,145
Kinase 2 | 634
GPCR 1 | 408

GO Process

positive regulation of smoothe... 26 | 26
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Protein inturned INTU Tbio Non-IDG -1.76006 53.9 56
Glypican-3 GPC3 Tbio Non-IDG -2.92699 862.1 768
Zinc finger protein GLI1 GLI1 Tchem Transcription Factor -3.04303 1054.8 450
Protein Wnt-9a WNT9A Tbio Non-IDG -1.41160 26.6 141
Secreted frizzled-related protein 1 SFRP1 Tchem Non-IDG -2.40092 279.5 264
Doublecortin domain-containing protein 2 DCDC2 Tbio Non-IDG -1.71331 52.4 209
NADPH--cytochrome P450 reductase POR Tbio Enzyme -2.43541 216.2 257
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Signal peptide, CUB and EGF-like domain-containing protein 1 SCUBE1 Tbio Non-IDG -1.36066 28.2 70