Development Level

Tbio 96 | 11,445
Tchem 43 | 1,598
Tclin 22 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 7 | 499
embryonic lethality prior to t... 6 | 278
abnormal embryo size 5 | 220
decreased vertical activity 5 | 208
increased circulating alkaline... 4 | 122
increased circulating choleste... 4 | 66
abnormal seminal vesicle morph... 3 | 114
decreased body weight 3 | 161
decreased circulating HDL chol... 3 | 68
decreased circulating aspartat... 3 | 34
decreased circulating serum al... 3 | 82
enlarged heart 3 | 210
increased circulating triglyce... 3 | 42
increased leukocyte cell numbe... 3 | 47
increased total body fat amoun... 3 | 134
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal sleep behavior 2 | 70
abnormal snout morphology 2 | 23
abnormal tooth morphology 2 | 24
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased heart weight 2 | 27
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
increased blood urea nitrogen ... 2 | 48
increased circulating HDL chol... 2 | 80
increased circulating iron lev... 2 | 30
increased mean corpuscular hem... 2 | 96
increased startle reflex 2 | 112
small superior vagus ganglion 2 | 74
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal limb bud morphology 1 | 17
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal whole-body plethysmog... 1 | 4
decreased blood urea nitrogen ... 1 | 51
decreased cardiac muscle contr... 1 | 11
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased food intake 1 | 13
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydroencephaly 1 | 14
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased eosinophil cell numb... 1 | 11
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
limb grasping 1 | 41
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prolonged PQ interval 1 | 5
short tibia 1 | 97
small testis 1 | 58
tremors 1 | 39

Disease

Atherosclerosis 113 | 291
Carcinoma 103 | 11,493
diabetes mellitus 102 | 1,728
Coronary artery disease 95 | 268
psoriasis 86 | 6,694
Obesity 82 | 678
Cancer 80 | 2,499
ovarian cancer 74 | 8,520
Lipid metabolism disorder 70 | 114
lung cancer 68 | 4,740
Hypertension 66 | 396
Kidney disease 65 | 430
osteosarcoma 65 | 7,950
Cerebrovascular disease 57 | 238
glioblastoma 54 | 5,792
invasive ductal carcinoma 54 | 2,951
Heart disease 52 | 306
malignant mesothelioma 48 | 3,232
non-small cell lung cancer 48 | 2,890
Liver disease 47 | 237
intraductal papillary-mucinous neoplasm (IPMN) 47 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 46 | 2,955
lung carcinoma 46 | 2,843
pancreatic cancer 46 | 2,398
Schizophrenia 45 | 1,160
Autosomal recessive predisposition 44 | 1,442
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,989
medulloblastoma, large-cell 44 | 6,241
lung adenocarcinoma 43 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 43 | 1,962
ependymoma 41 | 4,679
Hypertensive disease 39 | 292
atypical teratoid / rhabdoid tumor 39 | 5,112
interstitial cystitis 39 | 2,312
ulcerative colitis 39 | 1,819
Alzheimer's disease 38 | 658
Breast cancer 38 | 3,578
Fatty liver disease 38 | 103
Liver Cirrhosis, Experimental 38 | 769
tuberculosis 38 | 2,010
Hyperglycemia 37 | 137
ductal carcinoma in situ 37 | 1,745
cystic fibrosis 35 | 1,696
Arthritis 34 | 290
adult high grade glioma 34 | 3,801
Astrocytoma, Pilocytic 32 | 3,081
Anemia 31 | 365
Asthma 31 | 385
Prostatic Neoplasms 29 | 495
adrenocortical carcinoma 29 | 1,428
group 3 medulloblastoma 29 | 4,104
Heart failure 28 | 162
breast carcinoma 28 | 1,638
Hypersensitivity reaction type II disease 27 | 253
Kidney cancer 27 | 2,613
Lung disease 27 | 142
Cholestasis 26 | 155
Myocardial Infarction 26 | 151
Pancreatitis 26 | 123
Atopic dermatitis 25 | 952
Bipolar Disorder 25 | 666
Hyperinsulinism 25 | 133
Cardiovascular Diseases 24 | 59
Inflammatory bowel disease 24 | 151
Peripheral vascular disease 24 | 87
Rheumatoid arthritis 24 | 1,191
pituitary cancer 24 | 1,972
Brain disease 23 | 96
Depressive disorder 23 | 409
Polycystic ovary syndrome 23 | 360
Chemical and Drug Induced Liver Injury 22 | 195
Hypercholesterolemia 22 | 44
Vasculitis 22 | 80
oligodendroglioma 22 | 2,850
Inflammation 21 | 120
Major Depressive Disorder 21 | 301
subependymal giant cell astrocytoma 21 | 2,287
Cardiovascular system disease 20 | 246
Diabetic retinopathy 20 | 56
Kidney Failure, Chronic 20 | 46
Reperfusion Injury 20 | 86
astrocytic glioma 20 | 2,597
Alcoholic Intoxication, Chronic 19 | 289
Alzheimer Disease 19 | 83
Dementia 19 | 175
Diabetes Mellitus, Experimental 19 | 108
Diarrhea 19 | 253
Unipolar Depression 19 | 250
acute quadriplegic myopathy 19 | 1,158
Amyloidosis 18 | 67
Brain Ischemia 18 | 110
Diabetes Mellitus, Non-Insulin-Dependent 18 | 145
Multiple Sclerosis 18 | 540
Myocardial Ischemia 18 | 169
Thrombocytopenia 18 | 197
Vascular disease 18 | 319
active ulcerative colitis 18 | 764
cutaneous lupus erythematosus 18 | 1,057
esophageal adenocarcinoma 18 | 737
primitive neuroectodermal tumor 18 | 3,035

Tissue

Digestive Tract 161 | 17,369
Endocrine System 159 | 18,159
Liver and Pancreas 159 | 16,750
Female tissues 156 | 17,400
Skin and soft tissues 155 | 17,230
Urinary Tract 155 | 16,678
Male tissues 154 | 17,142
Nervous System 147 | 16,725
Blood and immune system 146 | 16,909
Respiratory system 146 | 16,393
Cardiovascular System 133 | 15,192

Target Family

Non-IDG 98 | 12,091
Enzyme 49 | 4,145
Transcription Factor 5 | 1,400
Kinase 4 | 634
Transporter 4 | 473
Nuclear Receptor 3 | 48
GPCR 1 | 408

Compartment GO Term

protein-lipid complex 164 | 164
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MICOS complex subunit MIC26 APOO Tbio Non-IDG -1.25338 18.9 141
Vigilin HDLBP Tbio Non-IDG -2.01228 106.9 233
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275