Development Level

Tbio 888 | 11,445
Tchem 368 | 1,598
Tclin 281 | 613
Tdark 156 | 6,588

Collection

RFA-RM-18-021 95 | 328
GPCR: IDG Consortium (Targets) 47 | 126
Ion Channel: IDG Consortium (T... 47 | 99
GPCR: IDG Consortium (Complete... 16 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 64 | 979
preweaning lethality, incomple... 51 | 499
abnormal behavior 37 | 298
decreased vertical activity 26 | 208
enlarged heart 25 | 210
decreased total body fat amoun... 22 | 207
embryonic lethality prior to t... 21 | 278
hyperactivity 20 | 148
abnormal bone structure 18 | 187
abnormal embryo size 18 | 220
increased lean body mass 18 | 172
abnormal heart morphology 17 | 162
decreased body weight 16 | 161
embryonic lethality prior to o... 16 | 239
abnormal seminal vesicle morph... 14 | 114
increased total body fat amoun... 14 | 134
impaired glucose tolerance 13 | 75
increased circulating alkaline... 13 | 122
increased mean corpuscular vol... 13 | 92
increased startle reflex 13 | 112
small superior vagus ganglion 13 | 74
decreased bone mineral content 12 | 151
decreased grip strength 12 | 116
decreased circulating insulin ... 11 | 76
decreased lymphocyte cell numb... 11 | 83
decreased prepulse inhibition 11 | 82
hypoactivity 11 | 132
increased bone mineral content 11 | 108
increased circulating sodium l... 11 | 71
abnormal epididymis morphology 10 | 42
abnormal gait 10 | 69
improved glucose tolerance 10 | 79
tremors 10 | 39
abnormal eye morphology 9 | 68
decreased erythrocyte cell num... 9 | 62
decreased fasted circulating g... 9 | 65
increased leukocyte cell numbe... 9 | 47
increased mean corpuscular hem... 9 | 96
limb grasping 9 | 41
abnormal kidney morphology 8 | 65
decreased bone mineral density 8 | 126
decreased circulating HDL chol... 8 | 68
decreased circulating alkaline... 8 | 46
decreased circulating choleste... 8 | 93
decreased lean body mass 8 | 135
decreased mean corpuscular vol... 8 | 79
increased circulating choleste... 8 | 66
increased monocyte cell number 8 | 63
prolonged ST segment 8 | 36
abnormal retina morphology 7 | 71
abnormal sleep behavior 7 | 70
cardiovascular system phenotyp... 7 | 36
cataract 7 | 92
decreased body length 7 | 101
decreased circulating glucose ... 7 | 126
decreased circulating triglyce... 7 | 79
embryonic growth retardation 7 | 106
enlarged epididymis 7 | 31
enlarged spleen 7 | 41
increased circulating HDL chol... 7 | 80
increased circulating chloride... 7 | 41
increased neutrophil cell numb... 7 | 46
prolonged QT interval 7 | 38
short tibia 7 | 97
abnormal behavioral response t... 6 | 66
abnormal lens morphology 6 | 81
abnormal skin morphology 6 | 50
decreased circulating LDL chol... 6 | 38
decreased circulating creatini... 6 | 39
decreased eosinophil cell numb... 6 | 24
edema 6 | 59
hydrometra 6 | 53
increased circulating triglyce... 6 | 42
increased erythrocyte cell num... 6 | 39
male infertility 6 | 123
pale yolk sac 6 | 25
pallor 6 | 34
thrombocytopenia 6 | 56
abnormal bone mineralization 5 | 38
abnormal testis morphology 5 | 43
decreased blood urea nitrogen ... 5 | 51
decreased circulating amylase ... 5 | 28
decreased circulating calcium ... 5 | 36
decreased circulating serum al... 5 | 82
decreased heart weight 5 | 27
decreased leukocyte cell numbe... 5 | 73
decreased mean corpuscular hem... 5 | 50
increased circulating amylase ... 5 | 25
increased circulating creatini... 5 | 38
increased circulating iron lev... 5 | 30
increased fasted circulating g... 5 | 76
increased grip strength 5 | 41
increased heart weight 5 | 62
increased hematocrit 5 | 46
increased lymphocyte cell numb... 5 | 32
increased mean platelet volume 5 | 45
mammalian phenotype 5 | 17
small testis 5 | 58
abnormal limb bud morphology 4 | 17
increased or absent threshold ... 4 | 101

Disease

Carcinoma 1,255 | 11,493
psoriasis 764 | 6,694
osteosarcoma 703 | 7,950
ovarian cancer 689 | 8,520
glioblastoma 625 | 5,792
medulloblastoma, large-cell 587 | 6,241
lung cancer 564 | 4,740
Cancer 514 | 2,499
atypical teratoid / rhabdoid tumor 512 | 5,112
ependymoma 488 | 4,679
lung carcinoma 470 | 2,843
adult high grade glioma 435 | 3,801
Astrocytoma, Pilocytic 409 | 3,081
non-small cell lung cancer 389 | 2,890
malignant mesothelioma 377 | 3,232
Kidney cancer 372 | 2,613
interstitial cystitis 367 | 2,312
Breast cancer 365 | 3,578
group 3 medulloblastoma 357 | 4,104
lung adenocarcinoma 355 | 2,716
invasive ductal carcinoma 352 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 343 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 340 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 339 | 2,989
pancreatic cancer 322 | 2,398
oligodendroglioma 304 | 2,850
diabetes mellitus 297 | 1,728
tuberculosis 284 | 2,010
primitive neuroectodermal tumor 283 | 3,035
ulcerative colitis 277 | 1,819
Schizophrenia 275 | 1,160
astrocytic glioma 266 | 2,597
subependymal giant cell astrocytoma 263 | 2,287
pituitary cancer 252 | 1,972
cystic fibrosis 239 | 1,696
Autosomal recessive predisposition 227 | 1,442
ductal carcinoma in situ 221 | 1,745
cutaneous lupus erythematosus 207 | 1,057
colon cancer 202 | 1,478
Rheumatoid arthritis 200 | 1,191
pancreatic ductal adenocarcinoma liver metastasis 194 | 1,962
breast carcinoma 186 | 1,638
Kidney disease 166 | 430
Pick disease 164 | 1,894
group 4 medulloblastoma 164 | 1,855
Multiple Sclerosis 162 | 540
Bipolar Disorder 157 | 666
Epilepsy 153 | 792
adrenocortical carcinoma 150 | 1,428
Arthritis 148 | 290
Hypersensitivity reaction type II disease 146 | 253
Hypertension 145 | 396
Liver Cirrhosis, Experimental 145 | 769
Melanoma 143 | 711
Obesity 142 | 678
primary pancreatic ductal adenocarcinoma 135 | 1,109
Depressive disorder 122 | 409
Asthma 121 | 385
dermatomyositis 119 | 966
Alzheimer's disease 118 | 658
astrocytoma 117 | 1,146
active Crohn's disease 116 | 922
Anemia 114 | 365
nasopharyngeal carcinoma 111 | 1,058
gastric carcinoma 110 | 807
pediatric high grade glioma 110 | 1,064
Intellectual disability 109 | 1,016
Skin cancer 106 | 469
Liver disease 105 | 237
Mental Depression 104 | 333
primary Sjogren syndrome 104 | 735
mucosa-associated lymphoid tissue lymphoma 102 | 484
active ulcerative colitis 101 | 764
Alcoholic Intoxication, Chronic 100 | 289
Atherosclerosis 100 | 291
Seizures 100 | 596
Atopic dermatitis 99 | 952
esophageal adenocarcinoma 99 | 737
juvenile dermatomyositis 95 | 1,187
Coronary artery disease 94 | 268
Liver cancer 94 | 604
Heart disease 93 | 306
Hypertensive disease 92 | 292
Acquired immunodeficiency syndrome 91 | 197
Autistic Disorder 90 | 364
Prostatic Neoplasms 88 | 495
spina bifida 88 | 1,074
Down syndrome 87 | 499
Vascular disease 87 | 319
Duchenne muscular dystrophy 86 | 601
Major Depressive Disorder 86 | 301
acute quadriplegic myopathy 86 | 1,158
Cerebrovascular disease 85 | 238
Breast Neoplasms 84 | 445
Endometriosis 84 | 540
Dermatitis 83 | 157
Mammary Neoplasms 83 | 425
Human immunodeficiency virus infectious disease 81 | 138
Parkinson's disease 81 | 392
aldosterone-producing adenoma 81 | 665

Tissue

Endocrine System 1,568 | 18,159
Digestive Tract 1,516 | 17,369
Female tissues 1,502 | 17,400
Nervous System 1,487 | 16,725
Skin and soft tissues 1,485 | 17,230
Male tissues 1,480 | 17,142
Blood and immune system 1,459 | 16,909
Liver and Pancreas 1,459 | 16,750
Urinary Tract 1,459 | 16,678
Respiratory system 1,397 | 16,393
Cardiovascular System 1,258 | 15,192

Target Family

Non-IDG 747 | 12,091
GPCR 258 | 408
Transporter 227 | 473
Ion Channel 217 | 344
Enzyme 148 | 4,145
Kinase 77 | 634
Transcription Factor 10 | 1,400
oGPCR 9 | 421

Compartment GO Term

Integral component of plasma m... 1,693 | 1,693
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.61667 619.4 0
Carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 Tbio Non-IDG -2.27709 182.9 314
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Post-GPI attachment to proteins factor 6 TMEM8A Tdark Non-IDG -0.56820 3.55 16
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Protocadherin gamma-A9 PCDHGA9 Tdark Non-IDG 0.51 0.72 31
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Protocadherin beta-14 PCDHB14 Tdark Non-IDG 0.78 0.14 90
Protocadherin beta-12 PCDHB12 Tdark Non-IDG 0.00000 88