Development Level

Tbio 14 | 11,445
Tchem 13 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal placenta size 1 | 20
abnormal testis morphology 1 | 43
decreased vertical activity 1 | 208
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
pallor 1 | 34
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 25 | 11,493
medulloblastoma, large-cell 20 | 6,241
ovarian cancer 18 | 8,520
glioblastoma 16 | 5,792
group 3 medulloblastoma 16 | 4,104
psoriasis 16 | 6,694
ependymoma 15 | 4,679
oligodendroglioma 15 | 2,850
osteosarcoma 15 | 7,950
adult high grade glioma 13 | 3,801
atypical teratoid / rhabdoid tumor 13 | 5,112
primitive neuroectodermal tumor 13 | 3,035
lung adenocarcinoma 11 | 2,716
Astrocytoma, Pilocytic 10 | 3,081
Cancer 10 | 2,499
astrocytic glioma 10 | 2,597
lung cancer 10 | 4,740
Kidney cancer 9 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
malignant mesothelioma 9 | 3,232
non-small cell lung cancer 9 | 2,890
Breast cancer 8 | 3,578
invasive ductal carcinoma 8 | 2,951
lung carcinoma 7 | 2,843
Carney complex 6 | 25
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Intellectual disability 5 | 1,016
Rheumatoid arthritis 5 | 1,191
Waldenstrons macroglobulinemia 5 | 765
colon cancer 5 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
nasopharyngeal carcinoma 5 | 1,058
pancreatic cancer 5 | 2,398
primary Sjogren syndrome 5 | 735
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Actinic keratosis 4 | 21
Autosomal recessive predisposition 4 | 1,442
Concave bridge of nose 4 | 195
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Depressive disorder 4 | 409
Orbital separation excessive 4 | 244
Parkinson's disease 4 | 392
Pick disease 4 | 1,894
Primary pigmented nodular adrenocortical disease 4 | 13
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
interstitial cystitis 4 | 2,312
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 1,819
Acquired metabolic disease 3 | 336
Acquired scoliosis 3 | 281
Autistic Disorder 3 | 364
Cardiomegaly 3 | 116
Colorectal Neoplasms 3 | 243
Cryptorchidism 3 | 296
Curvature of spine 3 | 282
Delayed speech and language development 3 | 112
Diabetes Mellitus, Experimental 3 | 108
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Heart disease 3 | 306
Hyperalgesia 3 | 83
Hypertensive disease 3 | 292
Language Delay 3 | 112
Liver Cirrhosis, Experimental 3 | 769
Liver cancer 3 | 604
Myopathy 3 | 185
Obesity 3 | 678
Osteoporosis 3 | 363
Prostatic Neoplasms 3 | 495
Psychotic Disorders 3 | 151
Seizures 3 | 596
Speech Delay 3 | 112
Speech impairment 3 | 112
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
ductal carcinoma in situ 3 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
sarcoidosis 3 | 370
Anteverted nostril 2 | 191
Brachycephaly 2 | 88
Congenital Epicanthus 2 | 177
Cushing's syndrome 2 | 48
Dysarthria 2 | 192
Epilepsy 2 | 792
Increased susceptibility to fractures 2 | 21
Short nose 2 | 132
Small nose 2 | 132
Strabismus 2 | 270
Substance-Related Disorders 2 | 115
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
severe Alzheimer's disease 2 | 47

Tissue

Male tissues 28 | 17,142
Endocrine System 27 | 18,159
Digestive Tract 26 | 17,369
Skin and soft tissues 26 | 17,230
Nervous System 25 | 16,725
Female tissues 24 | 17,400
Blood and immune system 23 | 16,909
Liver and Pancreas 23 | 16,750
Urinary Tract 23 | 16,678
Cardiovascular System 22 | 15,192
Respiratory system 22 | 16,393

Target Family

Kinase 14 | 634
Transcription Factor 8 | 1,400
Enzyme 4 | 4,145
Epigenetic 1 | 242
Non-IDG 1 | 12,091

WikiPathways Pathway

miRs in Muscle Cell Differenti... 28 | 28
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Serine/threonine-protein kinase D3 PRKD3 Tchem Kinase -1.23218 13.2 295
Epididymal sperm-binding protein 1 ELSPBP1 Tbio Non-IDG -1.16386 14.3 58
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Protein kinase C eta type PRKCH Tchem Kinase -1.79158 65.4 184
Paired box protein Pax-7 PAX7 Tbio Transcription Factor -2.70703 468.7 418
Protein kinase C delta type PRKCD Tclin Kinase -2.18452 141.4 804
Serine/threonine-protein kinase D1 PRKD1 Tchem Kinase -2.88440 775.2 667
Protein kinase C iota type PRKCI Tchem Kinase -1.71694 51.2 148