Development Level

Tbio 21 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal coat-hair pigmentatio... 2 | 64
enlarged heart 2 | 210
increased bone mineral content 2 | 108
increased heart weight 2 | 62
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal skin morphology 1 | 50
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
enlarged spleen 1 | 41
increased bone mineral density 1 | 72
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36

Disease

Carcinoma 22 | 11,493
ovarian cancer 21 | 8,520
glioblastoma 18 | 5,792
pancreatic cancer 18 | 2,398
osteosarcoma 16 | 7,950
psoriasis 16 | 6,694
Astrocytoma, Pilocytic 15 | 3,081
Breast cancer 15 | 3,578
Kidney cancer 15 | 2,613
atypical teratoid / rhabdoid tumor 15 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
invasive ductal carcinoma 15 | 2,951
medulloblastoma, large-cell 15 | 6,241
Duchenne muscular dystrophy 14 | 601
ependymoma 14 | 4,679
gastric carcinoma 14 | 807
nasopharyngeal carcinoma 14 | 1,058
ulcerative colitis 14 | 1,819
adult high grade glioma 13 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
lung adenocarcinoma 13 | 2,716
lung cancer 13 | 4,740
malignant mesothelioma 13 | 3,232
Becker muscular dystrophy 12 | 191
cystic fibrosis 12 | 1,696
juvenile dermatomyositis 12 | 1,187
limb girdle muscular dystrophy 2A 11 | 213
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Liver Cirrhosis, Experimental 9 | 769
ductal carcinoma in situ 9 | 1,745
group 3 medulloblastoma 9 | 4,104
interstitial cystitis 9 | 2,312
non-small cell lung cancer 9 | 2,890
primary pancreatic ductal adenocarcinoma 9 | 1,109
primitive neuroectodermal tumor 9 | 3,035
urothelial carcinoma 9 | 318
Abortion, Spontaneous 8 | 109
Spontaneous abortion 8 | 113
esophageal adenocarcinoma 8 | 737
interstitial lung disease 8 | 298
lung carcinoma 8 | 2,843
oligodendroglioma 8 | 2,850
subependymal giant cell astrocytoma 8 | 2,287
Acquired scoliosis 7 | 281
Autosomal recessive predisposition 7 | 1,442
Curvature of spine 7 | 282
Liver cancer 7 | 604
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
head and neck cancer 7 | 271
pterygium 7 | 76
Degenerative polyarthritis 6 | 115
Ehlers-Danlos syndrome 6 | 43
Short stature 6 | 531
dermatomyositis 6 | 966
diabetes mellitus 6 | 1,728
head and neck cancer and chronic obstructive pulmonary disease 6 | 239
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pituitary cancer 6 | 1,972
Congenital clubfoot 5 | 109
Ecchymosis 5 | 66
Highly variable severity 5 | 157
Increased tendency to bruise 5 | 66
Joint hyperflexibility 5 | 78
Joint laxity 5 | 54
Melanoma 5 | 711
Mitral Valve Prolapse Syndrome 5 | 39
Prominent ear 5 | 56
Protruding ears 5 | 56
Skin cancer 5 | 469
Skin hyperelastic 5 | 32
Soft skin 5 | 17
Thin skin 5 | 47
Variable expressivity 5 | 157
Velvety skin 5 | 17
adrenocortical carcinoma 5 | 1,428
Atopic dermatitis 4 | 952
Cancer 4 | 2,499
Cognitive delay 4 | 608
Creatine phosphokinase serum increased 4 | 110
DOID:2627 4 | 94
Elevated creatine kinase 4 | 110
Flatfoot 4 | 73
Gaucher disease type 1 4 | 180
Global developmental delay 4 | 608
Hernia, Inguinal 4 | 89
Liver Cirrhosis 4 | 181
Mental and motor retardation 4 | 608
Muscle hypotonia 4 | 571
Nephrotic Syndrome 4 | 78
Pectus excavatum 4 | 100
Proximal muscle weakness 4 | 47
Proximal neurogenic muscle weakness 4 | 47
Schizophrenia 4 | 1,160
Slow progression 4 | 89
X-linked cerebral adrenoleukodystrophy 4 | 116
acute quadriplegic myopathy 4 | 1,158
medulloblastoma 4 | 720
nephrosclerosis 4 | 333

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Non-IDG 22 | 12,091

WikiPathways Pathway

miRNA targets in ECM and membr... 22 | 22
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Collagen alpha-1(VI) chain COL6A1 Tbio Non-IDG -2.03348 104.7 204
Collagen alpha-2(VI) chain COL6A2 Tbio Non-IDG -1.80531 59.2 151
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Collagen alpha-3(VI) chain COL6A3 Tbio Non-IDG -1.79687 61.3 32
Collagen alpha-2(V) chain COL5A2 Tbio Non-IDG -1.69982 44.6 96
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
Collagen alpha-3(V) chain COL5A3 Tbio Non-IDG -0.80962 6.18 73
Collagen alpha-1(III) chain COL3A1 Tbio Non-IDG -2.58251 354.8 439