Development Level

Tbio 15 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal tooth morphology 3 | 24
preweaning lethality, complete... 3 | 979
decreased bone mineral content 2 | 151
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal heart left ventricle ... 1 | 16
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal lens morphology 1 | 81
abnormal response to new envir... 1 | 10
abnormal tibia morphology 1 | 14
absent ovary 1 | 3
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
small spleen 1 | 19

Disease

glioblastoma 14 | 5,792
Carcinoma 13 | 11,493
atypical teratoid / rhabdoid tumor 13 | 5,112
medulloblastoma, large-cell 13 | 6,241
ovarian cancer 13 | 8,520
Breast cancer 11 | 3,578
ependymoma 11 | 4,679
Astrocytoma, Pilocytic 10 | 3,081
adult high grade glioma 10 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
invasive ductal carcinoma 10 | 2,951
osteosarcoma 10 | 7,950
pancreatic cancer 10 | 2,398
Cancer 9 | 2,499
group 3 medulloblastoma 9 | 4,104
primitive neuroectodermal tumor 9 | 3,035
lung cancer 8 | 4,740
ulcerative colitis 8 | 1,819
gastric carcinoma 7 | 807
non-small cell lung cancer 7 | 2,890
Duchenne muscular dystrophy 6 | 601
Kidney cancer 6 | 2,613
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
breast carcinoma 6 | 1,638
interstitial cystitis 6 | 2,312
interstitial lung disease 6 | 298
juvenile dermatomyositis 6 | 1,187
nasopharyngeal carcinoma 6 | 1,058
pituitary cancer 6 | 1,972
psoriasis 6 | 6,694
Becker muscular dystrophy 5 | 191
Short stature 5 | 531
adrenocortical carcinoma 5 | 1,428
ductal carcinoma in situ 5 | 1,745
esophageal adenocarcinoma 5 | 737
limb girdle muscular dystrophy 2A 5 | 213
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary pancreatic ductal adenocarcinoma 5 | 1,109
pterygium 5 | 76
urothelial carcinoma 5 | 318
Acquired scoliosis 4 | 281
Autosomal recessive predisposition 4 | 1,442
Congenital Epicanthus 4 | 177
Curvature of spine 4 | 282
Flat face 4 | 52
Hypertension 4 | 396
Hypertensive disease 4 | 292
Hypoplastic mandible condyle 4 | 275
Liver Cirrhosis, Experimental 4 | 769
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Neoplasm Invasiveness 4 | 161
Soft skin 4 | 17
Velvety skin 4 | 17
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
lung carcinoma 4 | 2,843
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
Abortion, Spontaneous 3 | 109
Breast Neoplasms 3 | 445
Degenerative polyarthritis 3 | 115
Ecchymosis 3 | 66
Exophthalmos 3 | 112
Frontal bossing 3 | 157
Heart disease 3 | 306
Hernia, Inguinal 3 | 89
Increased tendency to bruise 3 | 66
Joint hyperflexibility 3 | 78
Keratoconus 3 | 113
Liver Cirrhosis 3 | 181
Malar flattening 3 | 129
Myopia 3 | 176
Neoplasm Metastasis 3 | 168
Osteoporosis 3 | 363
Pectus excavatum 3 | 100
Pick disease 3 | 1,894
Polycystic ovary syndrome 3 | 360
Premature Birth 3 | 77
Premature birth of newborn 3 | 67
Prominent ear 3 | 56
Prominent eyes 3 | 96
Prominent globes 3 | 96
Protruding ears 3 | 56
Protruding eyes 3 | 96
Respiratory Insufficiency 3 | 132
Respiratory function loss 3 | 121
Skin hyperelastic 3 | 32
Spontaneous abortion 3 | 113
Telecanthus 3 | 62
Thin skin 3 | 47
Umbilical hernia 3 | 93
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
nephrosclerosis 3 | 333

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Non-IDG 9 | 12,091
Transcription Factor 7 | 1,400
GPCR 1 | 408

WikiPathways Pathway

miR-509-3p alteration of YAP1/... 17 | 17
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
Pre-B-cell leukemia transcription factor 3 PBX3 Tbio Transcription Factor -1.58292 36.0 183
Endothelin-1 receptor EDNRA Tclin GPCR -2.86513 644.6 259
Collagen alpha-1(III) chain COL3A1 Tbio Non-IDG -2.58251 354.8 439
Collagen alpha-1(I) chain COL1A1 Tbio Non-IDG -2.98303 874.8 508
Transcriptional enhancer factor TEF-1 TEAD1 Tbio Transcription Factor -1.71108 45.2 164
SPARC SPARC Tbio Non-IDG -3.10194 1136.1 543
Collagen alpha-1(V) chain COL5A1 Tbio Non-IDG -2.07285 114.2 274