Development Level

Tbio 26 | 11,445
Tclin 9 | 613
Tchem 8 | 1,598

IMPC Phenotype

hyperactivity 2 | 148
increased circulating choleste... 2 | 66
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal ovary morphology 1 | 7
abnormal pupil morphology 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased cardiac muscle contr... 1 | 11
decreased circulating aspartat... 1 | 34
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged ovary 1 | 2
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38

Disease

Carcinoma 32 | 11,493
psoriasis 28 | 6,694
ovarian cancer 19 | 8,520
osteosarcoma 17 | 7,950
ependymoma 15 | 4,679
glioblastoma 15 | 5,792
Cancer 14 | 2,499
invasive ductal carcinoma 14 | 2,951
group 3 medulloblastoma 13 | 4,104
lung carcinoma 13 | 2,843
Astrocytoma, Pilocytic 12 | 3,081
ductal carcinoma in situ 12 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
pituitary cancer 12 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
medulloblastoma, large-cell 11 | 6,241
Breast cancer 10 | 3,578
Liver Cirrhosis, Experimental 10 | 769
Obesity 10 | 678
adult high grade glioma 10 | 3,801
atypical teratoid / rhabdoid tumor 10 | 5,112
breast carcinoma 10 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung cancer 10 | 4,740
fibroadenoma 9 | 559
lung adenocarcinoma 9 | 2,716
malignant mesothelioma 9 | 3,232
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
Autosomal recessive predisposition 8 | 1,442
Schizophrenia 8 | 1,160
non-small cell lung cancer 8 | 2,890
Lipid metabolism disorder 7 | 114
Prostatic Neoplasms 7 | 495
active ulcerative colitis 7 | 764
aldosterone-producing adenoma 7 | 665
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Coronary artery disease 6 | 268
Kaposi's Sarcoma Skin Lesions 6 | 8
Stomach Neoplasms 6 | 300
adrenocortical carcinoma 6 | 1,428
astrocytic glioma 6 | 2,597
esophageal adenocarcinoma 6 | 737
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
nasopharyngeal carcinoma 6 | 1,058
tuberculosis 6 | 2,010
Atherosclerosis 5 | 291
Cone dystrophy 5 | 71
Fatty liver disease 5 | 103
Fundus dystrophy 5 | 83
Intellectual disability 5 | 1,016
Pick disease 5 | 1,894
Retinitis Pigmentosa 5 | 226
diabetes mellitus 5 | 1,728
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
Alcohol dependence 4 | 107
Alcoholic Intoxication, Chronic 4 | 289
Animal Mammary Neoplasms 4 | 136
Atopic dermatitis 4 | 952
Autoimmune lymphoproliferative syndrome type 4 4 | 6
Broad flat nasal bridge 4 | 236
Chemical and Drug Induced Liver Injury 4 | 195
Difficulties with night vision 4 | 87
Dull intelligence 4 | 645
Fundus albipunctatus 4 | 10
Hyperinsulinism 4 | 133
Keratoconus 4 | 113
Kidney cancer 4 | 2,613
Low intelligence 4 | 645
Mammary Neoplasms, Animal 4 | 136
Mammary Neoplasms, Experimental 4 | 154
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Nasal bridge wide 4 | 236
Night Blindness 4 | 101
Poor school performance 4 | 645
Retinal Degeneration 4 | 106
Retinal Dystrophies 4 | 33
active Crohn's disease 4 | 922
astrocytoma 4 | 1,146
facioscapulohumeral dystrophy 4 | 288
mucosa-associated lymphoid tissue lymphoma 4 | 484
pancreatic cancer 4 | 2,398
Anteverted nostril 3 | 191
Cholestasis 3 | 155
Colonic Neoplasms 3 | 142
Endometriosis 3 | 540
Hypercholesterolemia 3 | 44
Hypertension 3 | 396
Low Vision 3 | 174
Lung Neoplasms 3 | 232
Myocardial Ischemia 3 | 169
Myopia 3 | 176
Primary cutaneous T-cell lymphoma 3 | 29
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic rhinosinusitis 3 | 512
pediatric high grade glioma 3 | 1,064

Tissue

Endocrine System 43 | 18,159
Digestive Tract 42 | 17,369
Female tissues 41 | 17,400
Male tissues 41 | 17,142
Liver and Pancreas 40 | 16,750
Skin and soft tissues 40 | 17,230
Nervous System 39 | 16,725
Urinary Tract 38 | 16,678
Blood and immune system 37 | 16,909
Respiratory system 36 | 16,393
Cardiovascular System 31 | 15,192

Target Family

Enzyme 22 | 4,145
Non-IDG 12 | 12,091
Nuclear Receptor 6 | 48
Transporter 2 | 473
Kinase 1 | 634

WikiPathways Pathway

Vitamin A and Carotenoid Metab... 43 | 43
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta,beta-carotene 9',10'-oxygenase BCO2 Tbio Enzyme -1.64030 46.1 93
Retinol-binding protein 2 RBP2 Tbio Non-IDG -2.08995 120.9 150
Acyl-CoA wax alcohol acyltransferase 2 AWAT2 Tbio Enzyme -1.73443 52.5 81
Cellular retinoic acid-binding protein 1 CRABP1 Tbio Non-IDG -2.48395 306.2 152
Retinal dehydrogenase 2 ALDH1A2 Tbio Enzyme -2.25078 175.3 229
Retinoid-binding protein 7 RBP7 Tbio Non-IDG -0.86335 6.26 89
Cytochrome P450 26A1 CYP26A1 Tchem Enzyme -2.44772 290.1 197
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139
Retinoic acid receptor RXR-beta RXRB Tclin Nuclear Receptor -1.72557 49.3 274