Development Level

Tbio 60 | 11,445
Tchem 7 | 1,598
Tclin 4 | 613

IMPC Phenotype

increased neutrophil cell numb... 2 | 46
preweaning lethality, complete... 2 | 979
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
decreased blood urea nitrogen ... 1 | 51
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased spleen weight 1 | 10
increased startle reflex 1 | 112
thrombocytopenia 1 | 56

Disease

Cancer 60 | 2,499
psoriasis 58 | 6,694
Arthritis 45 | 290
dermatomyositis 45 | 966
diabetes mellitus 45 | 1,728
Rheumatoid arthritis 44 | 1,191
Hypersensitivity reaction type II disease 42 | 253
Dermatitis 41 | 157
Human immunodeficiency virus infectious disease 40 | 138
Stevens-Johnson syndrome 38 | 92
Synovitis 38 | 78
Acquired immunodeficiency syndrome 37 | 197
Uveitis 37 | 103
Ankylosing spondylitis 36 | 140
Herpes zoster 36 | 68
Behcet's disease 35 | 89
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Juvenile rheumatoid arthritis 35 | 111
Nephritis 35 | 51
Psoriatic arthritis 35 | 86
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
lung cancer 22 | 4,740
osteosarcoma 22 | 7,950
Carcinoma 21 | 11,493
cutaneous lupus erythematosus 20 | 1,057
Multiple Sclerosis 19 | 540
glioblastoma 19 | 5,792
lung carcinoma 19 | 2,843
tuberculosis 19 | 2,010
ovarian cancer 18 | 8,520
interstitial cystitis 17 | 2,312
juvenile dermatomyositis 16 | 1,187
invasive ductal carcinoma 15 | 2,951
malignant mesothelioma 15 | 3,232
medulloblastoma, large-cell 15 | 6,241
pancreatic cancer 15 | 2,398
primary Sjogren syndrome 14 | 735
Astrocytoma, Pilocytic 13 | 3,081
Breast cancer 13 | 3,578
Liver Cirrhosis, Experimental 13 | 769
active Crohn's disease 13 | 922
ependymoma 13 | 4,679
Influenza 12 | 142
active ulcerative colitis 12 | 764
cystic fibrosis 12 | 1,696
Multiple myeloma 11 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
ulcerative colitis 11 | 1,819
Hepatitis C 10 | 94
astrocytoma 10 | 1,146
atypical teratoid / rhabdoid tumor 10 | 5,112
breast carcinoma 10 | 1,638
lung adenocarcinoma 10 | 2,716
Autosomal recessive predisposition 9 | 1,442
Microphthalmia with limb anomalies 9 | 40
adult high grade glioma 9 | 3,801
nasopharyngeal carcinoma 9 | 1,058
Asthma 8 | 385
Influenza, Human 8 | 51
Myocardial Ischemia 8 | 169
Systemic lupus erythematosus 8 | 194
esophageal adenocarcinoma 8 | 737
group 4 medulloblastoma 8 | 1,855
non-small cell lung cancer 8 | 2,890
subependymal giant cell astrocytoma 8 | 2,287
Atopic dermatitis 7 | 952
Fever 7 | 138
Inflammatory bowel disease 7 | 151
Lung disease 7 | 142
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
pancreatic carcinoma 7 | 562
sarcoidosis 7 | 370
Anemia 6 | 365
Atherosclerosis 6 | 291
Diabetes Mellitus, Experimental 6 | 108
Encephalitis 6 | 64
Hepatitis 6 | 67
Hypertensive disease 6 | 292
Kidney disease 6 | 430
Malaria 6 | 160
Myocardial Infarction 6 | 151
Vascular disease 6 | 319
head and neck cancer 6 | 271
head and neck cancer and chronic obstructive pulmonary disease 6 | 239
hepatocellular carcinoma 6 | 547
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pituitary cancer 6 | 1,972
Arthritis, Rheumatoid 5 | 174
Bipolar Disorder 5 | 666
Kidney cancer 5 | 2,613
Schizophrenia 5 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
oligodendroglioma 5 | 2,850
periodontitis 5 | 293
primary pancreatic ductal adenocarcinoma 5 | 1,109
urothelial carcinoma 5 | 318

Tissue

Blood and immune system 36 | 16,909
Cardiovascular System 35 | 15,192
Digestive Tract 35 | 17,369
Endocrine System 35 | 18,159
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Respiratory system 35 | 16,393
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678

Target Family

Non-IDG 54 | 12,091
Transcription Factor 8 | 1,400
Enzyme 4 | 4,145
Kinase 4 | 634
Ion Channel 1 | 344

WikiPathways Pathway

Type II interferon signaling (... 71 | 71
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.35134 2277.5 752
Cytochrome b-245 heavy chain CYBB Tchem Ion Channel -3.09698 1276.8 315
2'-5'-oligoadenylate synthase 1 OAS1 Tbio Enzyme -2.01318 92.3 238
HLA class I histocompatibility antigen, B-58 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
MHC class II transactivator CIITA Tbio Non-IDG -2.63957 506.8 146
HLA class I histocompatibility antigen, B-82 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Interferon alpha-inducible protein 6 IFI6 Tbio Non-IDG -1.22757 16.7 120
Protein kinase C delta type PRKCD Tclin Kinase -2.18452 141.4 804