Development Level

Tbio 10 | 10,625
Tchem 7 | 1,890
Tclin 5 | 602

IMPC Term

cardiovascular system phenotyp... 1 | 35
decreased blood urea nitrogen ... 1 | 31
decreased circulating LDL chol... 1 | 37
decreased fasted circulating g... 1 | 49
impaired glucose tolerance 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating iron lev... 1 | 25
increased mean corpuscular hem... 1 | 93
preweaning lethality, complete... 1 | 633

Disease

Cancer 12 | 2,346
diabetes mellitus 12 | 1,663
Hyperglycemia 11 | 120
osteosarcoma 10 | 7,933
psoriasis 10 | 6,685
Diabetes Mellitus, Non-Insulin-Dependent 9 | 157
Obesity 9 | 616
ovarian cancer 9 | 8,484
Diabetes Mellitus, Experimental 8 | 106
Hyperinsulinism 7 | 63
Metabolic syndrome X 7 | 155
Alzheimer's disease 6 | 644
Insulin Resistance 6 | 48
glioblastoma 6 | 5,572
medulloblastoma, large-cell 6 | 6,234
Carcinoma 5 | 2,147
Polycystic Ovary Syndrome 5 | 332
atypical teratoid / rhabdoid tumor 5 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
pilocytic astrocytoma 5 | 3,086
Arthritis 4 | 248
Breast cancer 4 | 3,094
Fatty liver disease 4 | 84
Hypertensive disease 4 | 193
Hypoglycemia 4 | 81
Kidney disease 4 | 396
Lipid metabolism disorder 4 | 102
Parkinson's disease 4 | 364
Vascular disease 4 | 281
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
invasive ductal carcinoma 4 | 2,950
oligodendroglioma 4 | 2,849
spina bifida 4 | 1,064
Anemia 3 | 252
Brain disease 3 | 83
Coronary artery disease 3 | 240
Diabetes Mellitus, Insulin-Dependent 3 | 76
Epilepsy 3 | 346
Heart disease 3 | 279
Hyperalgesia 3 | 71
Hypertension 3 | 287
Insulinoma 3 | 20
Intellectual disability 3 | 573
Lipodystrophy 3 | 32
Liver carcinoma 3 | 217
Myocardial Ischemia 3 | 169
Neurodegenerative disease 3 | 383
Osteoporosis 3 | 257
Rheumatoid Arthritis 3 | 1,160
Schizophrenia 3 | 501
Stomach Neoplasms 3 | 282
Type 2 diabetes mellitus 3 | 189
acute myeloid leukemia 3 | 780
adult high grade glioma 3 | 2,148
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
dermatomyositis 3 | 933
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 2,514
group 3 medulloblastoma 3 | 2,254
lung carcinoma 3 | 2,844
malignant mesothelioma 3 | 3,162
maturity-onset diabetes of the young 3 | 28
primitive neuroectodermal tumor 3 | 3,031
subependymal giant cell astrocytoma 3 | 2,287
Acquired metabolic disease 2 | 267
Atherosclerosis 2 | 275
Brain Ischemia 2 | 87
Cardiomyopathies 2 | 90
Cerebrovascular disease 2 | 231
Coronary Restenosis 2 | 8
Crohn Disease 2 | 97
Drug-Induced Liver Injury 2 | 118
Exanthem 2 | 39
Glycogen storage disease 2 | 37
Gout 2 | 93
Hyperandrogenism 2 | 32
Inflammation 2 | 109
Leukopenia 2 | 42
Lung Neoplasms 2 | 171
Lung disease 2 | 132
Multiple Sclerosis 2 | 498
Neoplasm Metastasis 2 | 138
Neuropathy 2 | 210
Pancreatic Neoplasm 2 | 79
Reperfusion Injury 2 | 84
Seizures 2 | 95
Thrombocytopenia 2 | 105
Toxic encephalopathy 2 | 131
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
breast carcinoma 2 | 1,614
esophageal adenocarcinoma 2 | 737
medulloblastoma 2 | 1,524
mucosa-associated lymphoid tissue lymphoma 2 | 480
nephrosclerosis 2 | 329
tuberculosis 2 | 1,557
tuberculosis and treatment for 6 months 2 | 686

Tissue

Digestive Tract 22 | 18,473
Endocrine System 22 | 18,512
Liver and Pancreas 22 | 18,136
Nervous System 22 | 18,561
Blood and immune system 21 | 17,995
Female tissues 21 | 18,647
Male tissues 21 | 17,969
Skin and soft tissues 21 | 18,115
Cardiovascular System 20 | 17,958
Urinary Tract 20 | 18,444
Respiratory system 19 | 17,484

Target Family

Kinase 9 | 634
Non-IDG 6 | 11,971
Ion Channel 2 | 341
Transcription Factor 2 | 1,400
Transporter 2 | 473
Enzyme 1 | 4,146

WikiPathways Pathway

Type II diabetes mellitus 22 | 22
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.33707 243.8 508
Phosphorylase b kinase regulatory subunit alpha, liver isoform PHKA2 Tbio Kinase -2.16150 149.4 57
Transcription factor MafA MAFA Tbio Transcription Factor -1.32478 22.5 154
Phosphoinositide 3-kinase regulatory subunit 5 PIK3R5 Tbio Enzyme -1.46850 26.8 198
Suppressor of cytokine signaling 4 SOCS4 Tbio Non-IDG -1.16682 13.8 196
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.12872 1138.1 1044
Insulin, isoform 2 INS-IGF2 Tbio Non-IDG 7.55 71
Tumor necrosis factor TNF Tclin Non-IDG -4.68994 50044.6 2261
Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 Tchem Transporter -2.76812 575.0 235