Development Level

Tbio 22 | 10,625
Tchem 18 | 1,890
Tclin 6 | 602

IMPC Term

abnormal behavior 3 | 226
abnormal lens morphology 2 | 73
decreased mean corpuscular vol... 2 | 50
decreased total body fat amoun... 2 | 186
increased red blood cell distr... 2 | 21
preweaning lethality, complete... 2 | 633
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
cataract 1 | 26
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating insulin ... 1 | 75
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased prepulse inhibition 1 | 52
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased circulating alkaline... 1 | 119
increased circulating creatini... 1 | 29
increased circulating insulin ... 1 | 2
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38

Disease

ovarian cancer 26 | 8,492
psoriasis 26 | 6,685
lung cancer 20 | 4,473
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
interstitial cystitis 15 | 2,299
osteosarcoma 15 | 7,933
invasive ductal carcinoma 14 | 2,950
medulloblastoma, large-cell 14 | 6,234
ductal carcinoma in situ 13 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,956
pituitary cancer 13 | 1,972
Cancer 12 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
lung carcinoma 12 | 2,844
lung adenocarcinoma 11 | 2,714
ulcerative colitis 11 | 2,087
Prostatic Neoplasms 10 | 471
adrenocortical carcinoma 10 | 1,427
colon cancer 10 | 1,475
Atopic dermatitis 9 | 944
breast carcinoma 9 | 1,614
glioblastoma 9 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
malignant mesothelioma 9 | 3,163
pancreatic cancer 9 | 2,300
posterior fossa group A ependymoma 9 | 1,511
cutaneous lupus erythematosus 8 | 1,056
non-small cell lung cancer 8 | 2,798
tuberculosis 8 | 1,563
Mammary Neoplasms 7 | 410
group 3 medulloblastoma 7 | 2,254
oligodendroglioma 7 | 2,849
Autistic Disorder 6 | 320
active Crohn's disease 6 | 918
astrocytic glioma 6 | 2,241
atypical teratoid / rhabdoid tumor 6 | 4,369
pilocytic astrocytoma 6 | 3,086
primitive neuroectodermal tumor 6 | 3,031
Alcohol dependence 5 | 107
Alzheimer's disease 5 | 644
Breast cancer 5 | 3,099
Obesity 5 | 616
Peripheral Neuropathy 5 | 303
Schizophrenia 5 | 503
acute quadriplegic myopathy 5 | 1,157
diabetes mellitus 5 | 1,663
ependymoma 5 | 2,514
esophageal adenocarcinoma 5 | 737
pediatric high grade glioma 5 | 2,712
primary Sjogren syndrome 5 | 789
Carcinoma 4 | 2,147
Cardiomegaly 4 | 66
Endometriosis 4 | 535
Fatty Liver 4 | 48
Liver disease 4 | 219
Male infertility 4 | 170
Parkinson's disease 4 | 364
Pellagra 4 | 25
Precancerous Conditions 4 | 69
Waldenstrons macroglobulinemia 4 | 765
chronic rhinosinusitis 4 | 512
cystic fibrosis 4 | 1,670
dermatomyositis 4 | 967
fibroadenoma 4 | 557
group 4 medulloblastoma 4 | 1,875
juvenile dermatomyositis 4 | 1,189
subependymal giant cell astrocytoma 4 | 2,287
Adenocarcinoma 3 | 115
Asthma 3 | 349
Colorectal Neoplasms 3 | 217
Epilepsy 3 | 346
Hypertension 3 | 293
Hypertensive disease 3 | 193
Intellectual disability 3 | 573
Kidney disease 3 | 397
Liver Cirrhosis, Experimental 3 | 108
Lung Neoplasms 3 | 171
Major Depressive Disorder 3 | 106
Multiple myeloma 3 | 1,328
Neoplastic Cell Transformation 3 | 81
Parkinson Disease 3 | 105
Succinic semialdehyde dehydrogenase deficiency 3 | 16
Toxic encephalopathy 3 | 131
acute myeloid leukemia 3 | 785
adult high grade glioma 3 | 2,148
aldosterone-producing adenoma 3 | 664
astrocytoma 3 | 1,493
cystic fibrosis and chronic rhinosinusitis 3 | 213
gastric carcinoma 3 | 832
head and neck cancer 3 | 270
head and neck cancer and chronic obstructive pulmonary disease 3 | 237
hereditary spastic paraplegia 3 | 313
inflammatory breast cancer 3 | 404
medulloblastoma 3 | 1,524
mucosa-associated lymphoid tissue lymphoma 3 | 480
nasopharyngeal carcinoma 3 | 1,056
nephrosclerosis 3 | 329
non-small cell lung carcinoma 3 | 413
spina bifida 3 | 1,064
substance-related disorder 3 | 105

Tissue

Digestive Tract 46 | 18,473
Endocrine System 46 | 18,512
Female tissues 46 | 18,647
Liver and Pancreas 46 | 18,136
Nervous System 46 | 18,561
Respiratory system 46 | 17,484
Skin and soft tissues 46 | 18,115
Urinary Tract 46 | 18,444
Blood and immune system 45 | 17,995
Cardiovascular System 45 | 17,958
Male tissues 45 | 17,969

Target Family

Enzyme 36 | 4,146
Non-IDG 9 | 11,969
Epigenetic 1 | 242

WikiPathways Pathway

Tryptophan metabolism 46 | 46
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tryptophan 5-hydroxylase 1 TPH1 Tclin Enzyme -2.90440 740.7 364
3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 Tbio Enzyme -2.11508 131.7 319
4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 Tchem Enzyme -1.43796 24.7 139
Protein arginine N-methyltransferase 1 PRMT1 Tchem Epigenetic -2.30739 200.5 309
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.39018 2431.7 224
Retinal dehydrogenase 2 ALDH1A2 Tchem Enzyme -2.23286 171.4 208
Cytochrome P450 4F12 CYP4F12 Tchem Non-IDG -0.88873 8.32 0
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.28279 189.3 264
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.39065 2174.7 1062
Retinal dehydrogenase 1 ALDH1A1 Tchem Enzyme -2.76440 583.4 632