Development Level

Tbio 12 | 10,625
Tchem 9 | 1,890
Tclin 2 | 602
Tdark 1 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased bone mineral content 2 | 157
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased lactate dehydrogenas... 1 | 14
decreased mean corpuscular vol... 1 | 50
embryonic lethality prior to t... 1 | 187
increased fasted circulating g... 1 | 68
increased heart rate variabili... 1 | 4
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased total body fat amoun... 1 | 57
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260

Disease

psoriasis 16 | 6,685
ductal carcinoma in situ 11 | 1,745
invasive ductal carcinoma 11 | 2,950
medulloblastoma, large-cell 10 | 6,234
ovarian cancer 9 | 8,484
Atopic dermatitis 8 | 944
glioblastoma 8 | 5,572
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Obesity 7 | 616
breast carcinoma 7 | 1,614
diabetes mellitus 7 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
osteosarcoma 7 | 7,933
atypical teratoid / rhabdoid tumor 6 | 4,369
lung cancer 6 | 4,466
pilocytic astrocytoma 6 | 3,086
primitive neuroectodermal tumor 6 | 3,031
Breast cancer 5 | 3,094
Lipid metabolism disorder 5 | 102
fibroadenoma 5 | 557
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
malignant mesothelioma 5 | 3,162
Pick disease 4 | 1,893
Rheumatoid Arthritis 4 | 1,160
active Crohn's disease 4 | 918
acute quadriplegic myopathy 4 | 1,157
group 4 medulloblastoma 4 | 1,875
lung adenocarcinoma 4 | 2,713
non-small cell lung cancer 4 | 2,798
pediatric high grade glioma 4 | 2,712
tuberculosis 4 | 1,557
ulcerative colitis 4 | 2,087
Cardiovascular system disease 3 | 194
Coronary artery disease 3 | 240
Fatty liver disease 3 | 84
Metabolic syndrome X 3 | 155
adult high grade glioma 3 | 2,148
dermatomyositis 3 | 933
interstitial cystitis 3 | 2,299
lung carcinoma 3 | 2,844
nephrosclerosis 3 | 329
posterior fossa group B ependymoma 3 | 1,530
sonic hedgehog group medulloblastoma 3 | 1,482
subependymal giant cell astrocytoma 3 | 2,287
Atherosclerosis 2 | 275
Cataract 2 | 104
Chondrodysplasia punctata 2 | 41
Coronary heart disease 2 | 59
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Hypercholesterolemia, Familial 2 | 16
Hyperlipidemia 2 | 25
Hypertriglyceridemia 2 | 18
Rhizomelic chondrodysplasia punctata 2 | 11
Type 2 diabetes mellitus 2 | 189
Vascular disease 2 | 281
astrocytic glioma 2 | 2,241
astrocytoma 2 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
colon cancer 2 | 1,475
cutaneous lupus erythematosus 2 | 1,056
group 3 medulloblastoma 2 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
juvenile dermatomyositis 2 | 1,189
medulloblastoma 2 | 1,524
mucosa-associated lymphoid tissue lymphoma 2 | 480
non primary Sjogren syndrome sicca 2 | 840
oligodendroglioma 2 | 2,849
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 1,511
tuberculosis and treatment for 3 months 2 | 327
tuberculosis and treatment for 6 months 2 | 686
Adrenoleukodystrophy 1 | 31
Animal Mammary Neoplasms 1 | 136
Cardiomyopathies 1 | 90
Cardiovascular Diseases 1 | 50
Charcot-Marie-Tooth disease 1 | 74
Chronic Lymphocytic Leukemia 1 | 242
Colonic Neoplasms 1 | 126
Disease Progression 1 | 125
Drug-Induced Liver Injury 1 | 118
Fungal meningitis 1 | 7
Hepatitis C 1 | 90
Hypercholesterolemia 1 | 27
Hypertension 1 | 287
Hypertensive disease 1 | 193
IGA Glomerulonephritis 1 | 454
Infantile refsum disease 1 | 19
Mammary Neoplasms, Experimental 1 | 150
Melanoma 1 | 261
Myopathy 1 | 128
Necrosis 1 | 51
Peripheral vascular disease 1 | 90
Refsum disease 1 | 21
Spastic quadriplegia 1 | 7
Status Epilepticus 1 | 85
Stomach Neoplasms 1 | 282
Zellweger Syndrome 1 | 38
active ulcerative colitis 1 | 477
permanent atrial fibrillation 1 | 44

Tissue

Blood and immune system 24 | 17,995
Digestive Tract 24 | 18,473
Endocrine System 24 | 18,512
Female tissues 24 | 18,647
Liver and Pancreas 24 | 18,136
Nervous System 24 | 18,561
Skin and soft tissues 24 | 18,115
Urinary Tract 24 | 18,444
Cardiovascular System 23 | 17,958
Male tissues 23 | 17,969
Respiratory system 22 | 17,484

Target Family

Enzyme 22 | 4,146
Kinase 2 | 634

WikiPathways Pathway

Triacylglyceride Synthesis 24 | 24
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
1-acyl-sn-glycerol-3-phosphate acyltransferase beta AGPAT2 Tchem Enzyme -1.92659 87.1 108
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha AGPAT1 Tbio Enzyme -0.93422 7.85 75
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon AGPAT5 Tbio Enzyme -0.69876 4.42 156
Phospholipid phosphatase 2 PLPP2 Tbio Enzyme -1.33131 20.8 93
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tchem Enzyme -1.84739 75.6 147
2-acylglycerol O-acyltransferase 1 MOGAT1 Tbio Enzyme -1.02225 10.6 67
2-acylglycerol O-acyltransferase 3 MOGAT3 Tbio Enzyme -1.00860 10.7 59
Diacylglycerol O-acyltransferase 2 DGAT2 Tchem Enzyme -1.99022 99.0 208
Hepatic triacylglycerol lipase LIPC Tchem Enzyme -2.55928 388.4 241
Dihydroxyacetone phosphate acyltransferase GNPAT Tchem Enzyme -1.73003 66.7 149