Development Level

Tbio 12 | 11,178
Tchem 9 | 1,885
Tclin 2 | 612
Tdark 1 | 6,569

IMPC Phenotype

decreased bone mineral content 2 | 151
preweaning lethality, incomple... 2 | 499
abnormal heart morphology 1 | 162
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, complete... 1 | 979

Disease

psoriasis 17 | 6,514
Carcinoma 15 | 11,192
ductal carcinoma in situ 11 | 1,686
invasive ductal carcinoma 11 | 2,867
medulloblastoma, large-cell 10 | 6,086
ovarian cancer 9 | 8,297
Atopic dermatitis 8 | 915
Autosomal recessive predisposition 8 | 1,407
Obesity 8 | 655
glioblastoma 8 | 5,635
lung cancer 8 | 4,607
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,911
breast carcinoma 7 | 1,589
diabetes mellitus 7 | 1,683
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,204
osteosarcoma 7 | 7,766
tuberculosis 7 | 1,963
Astrocytoma, Pilocytic 6 | 3,006
atypical teratoid / rhabdoid tumor 6 | 4,971
primitive neuroectodermal tumor 6 | 2,957
Breast cancer 5 | 3,469
Hypertriglyceridemia result 5 | 35
Lipid metabolism disorder 5 | 111
adult high grade glioma 5 | 3,701
fibroadenoma 5 | 538
group 3 medulloblastoma 5 | 4,002
group 4 medulloblastoma 5 | 1,806
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,872
malignant mesothelioma 5 | 3,135
Liver Cirrhosis, Experimental 4 | 733
Pick disease 4 | 1,856
Rheumatoid arthritis 4 | 1,156
active Crohn's disease 4 | 882
acute quadriplegic myopathy 4 | 1,133
lung adenocarcinoma 4 | 2,627
non-small cell lung cancer 4 | 2,799
Cardiovascular system disease 3 | 240
Coronary artery disease 3 | 253
Dull intelligence 3 | 634
Fatty liver disease 3 | 102
Hepatomegaly 3 | 280
Hyperlipidemia 3 | 43
Insulin Resistance 3 | 70
Intellectual disability 3 | 998
Lipodystrophy 3 | 37
Low intelligence 3 | 634
Mental Retardation 3 | 634
Mental deficiency 3 | 634
Polycystic ovary syndrome 3 | 348
Poor school performance 3 | 634
Steatohepatitis 3 | 44
active ulcerative colitis 3 | 736
astrocytic glioma 3 | 2,530
dermatomyositis 3 | 941
interstitial cystitis 3 | 2,237
lung carcinoma 3 | 2,755
nephrosclerosis 3 | 314
posterior fossa group B ependymoma 3 | 406
subependymal giant cell astrocytoma 3 | 2,230
Acanthosis Nigricans 2 | 26
Atherosclerosis 2 | 276
Cataract 2 | 290
Chondrodysplasia punctata 2 | 40
Decreased serum leptin 2 | 6
Down syndrome 2 | 480
Duchenne muscular dystrophy 2 | 587
Dyslipidemias 2 | 27
Failure to gain weight 2 | 359
Hypercholesterolemia 2 | 43
Hypercholesterolemia, Familial 2 | 22
Hyperinsulinism 2 | 128
Hyperlipidemias 2 | 17
Hyperlipoproteinemia Type II 2 | 12
Hypertriglyceridemia 2 | 17
Metabolic syndrome X 2 | 52
Myopathy 2 | 185
Pediatric failure to thrive 2 | 359
Rhizomelia 2 | 24
Rhizomelic chondrodysplasia punctata 2 | 11
Schizophrenia 2 | 1,136
Sclerocystic Ovaries 2 | 14
Serum cholesterol raised 2 | 22
Short stature 2 | 514
Short upper arms 2 | 14
Splenomegaly 2 | 186
Type 2 diabetes mellitus 2 | 268
Vascular disease 2 | 294
Vomiting 2 | 116
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 492
colon cancer 2 | 1,428
cutaneous lupus erythematosus 2 | 1,016
ependymoma 2 | 4,559
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,902
juvenile dermatomyositis 2 | 1,147
mucosa-associated lymphoid tissue lymphoma 2 | 473
non primary Sjogren syndrome sicca 2 | 861
oligodendroglioma 2 | 2,768
pediatric high grade glioma 2 | 1,035
pituitary cancer 2 | 1,915
ulcerative colitis 2 | 1,765

Tissue

Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Male tissues 23 | 17,142
Urinary Tract 23 | 16,678
Blood and immune system 22 | 16,909
Liver and Pancreas 22 | 16,750
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Cardiovascular System 21 | 15,192

Target Family

Enzyme 22 | 4,145
Kinase 2 | 634

WikiPathways Pathway

Triacylglyceride Synthesis 24 | 24
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lipoprotein lipase LPL Tchem Enzyme -3.09646 876.3 338
1-acyl-sn-glycerol-3-phosphate acyltransferase delta AGPAT4 Tbio Enzyme -1.00407 9.73 165
Diacylglycerol O-acyltransferase 2 DGAT2 Tchem Enzyme -2.07482 112.0 230
2-acylglycerol O-acyltransferase 1 MOGAT1 Tbio Enzyme -1.07460 11.2 80
2-acylglycerol O-acyltransferase 3 MOGAT3 Tbio Enzyme -1.00860 10.7 81
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon AGPAT5 Tbio Enzyme -0.79526 4.42 180
Phospholipid phosphatase 2 PLPP2 Tbio Enzyme -1.34465 21.0 105
Dihydroxyacetone phosphate acyltransferase GNPAT Tchem Enzyme -1.82166 68.1 178
Phospholipid phosphatase 3 PLPP3 Tbio Enzyme -1.77858 65.1 94
Diacylglycerol O-acyltransferase 1 DGAT1 Tclin Enzyme -2.74425 562.7 211