Development Level

Tchem 8 | 1,598
Tbio 5 | 11,445
Tclin 2 | 613

IMPC Phenotype

abnormal optic disc morphology 1 | 10
abnormal vitreous body morphol... 1 | 10
decreased total body fat amoun... 1 | 207
increased circulating glucose ... 1 | 24
increased lean body mass 1 | 172

Disease

Cancer 13 | 2,499
lung cancer 12 | 4,740
ovarian cancer 11 | 8,520
psoriasis 11 | 6,694
Carcinoma 10 | 11,493
glioblastoma 10 | 5,792
Breast cancer 8 | 3,578
medulloblastoma, large-cell 8 | 6,241
Schizophrenia 7 | 1,160
osteosarcoma 7 | 7,950
Toxic encephalopathy 6 | 141
atypical teratoid / rhabdoid tumor 6 | 5,112
group 3 medulloblastoma 6 | 4,104
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
Kidney disease 5 | 430
Parkinson's disease 5 | 392
Prostatic Neoplasms 5 | 495
astrocytoma 5 | 1,146
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
tuberculosis 5 | 2,010
Carcinoma, Non-Small-Cell Lung 4 | 107
Contact Dermatitis 4 | 81
Dermatitis, Contact 4 | 71
Hyperglycemia 4 | 137
Obesity 4 | 678
Vascular disease 4 | 319
adult high grade glioma 4 | 3,801
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
ependymoma 4 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
non-small cell lung carcinoma 4 | 317
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
Acute kidney injury 3 | 70
Alzheimer's disease 3 | 658
Asthma 3 | 385
Autosomal recessive predisposition 3 | 1,442
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Chemical and Drug Induced Liver Injury 3 | 195
Diabetes Mellitus, Experimental 3 | 108
Heart disease 3 | 306
Hyperplasia 3 | 27
Liver Cirrhosis, Experimental 3 | 769
Liver cancer 3 | 604
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Mammary Neoplasms 3 | 425
Multiple myeloma 3 | 1,332
Pulmonary Fibrosis 3 | 106
Stomach Neoplasms 3 | 300
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
nasopharyngeal carcinoma 3 | 1,058
non primary Sjogren syndrome sicca 3 | 891
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Adenocarcinoma of lung 2 | 142
Anemia 2 | 365
Arthritis 2 | 290
Cholestasis 2 | 155
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Depressive disorder 2 | 409
Disease Progression 2 | 136
Down syndrome 2 | 499
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Epilepsy 2 | 792
Esophageal carcinoma 2 | 16
Hypertension 2 | 396
Liver diseases 2 | 87
Liver neoplasms 2 | 130
Lung disease 2 | 142
Microstomia 2 | 78
Myocardial Ischemia 2 | 169
Myopia 2 | 176
Parkinson Disease 2 | 64
Reperfusion Injury 2 | 86
Seizures 2 | 596
Smooth philtrum 2 | 43
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
mucosa-associated lymphoid tissue lymphoma 2 | 484
spina bifida 2 | 1,074

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Cardiovascular System 14 | 15,192

Target Family

Enzyme 6 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400
Non-IDG 1 | 12,091
Transporter 1 | 473

WikiPathways Pathway

Transcriptional activation by ... 15 | 15
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NAD(P)H dehydrogenase [quinone] 1 NQO1 Tchem Enzyme -3.12097 1326.4 550
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Kelch-like ECH-associated protein 1 KEAP1 Tclin Non-IDG -2.99364 962.4 463
Transcription factor Maf MAF Tbio Transcription Factor -2.90599 758.8 291
Nuclear factor erythroid 2-related factor 2 NFE2L2 Tchem Transcription Factor -3.14284 1506.7 552
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 AIMP2 Tbio Enzyme -1.35413 26.1 138
Glutamate--cysteine ligase regulatory subunit GCLM Tbio Enzyme -2.23855 156.3 277
Glutamate--cysteine ligase catalytic subunit GCLC Tchem Enzyme -2.48963 294.6 293
Cystine/glutamate transporter SLC7A11 Tchem Transporter -2.65482 430.0 227
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform PIK3CA Tclin Kinase -3.04988 1076.8 484