Development Level

Tbio 15 | 11,445
Tclin 6 | 613
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal gait 1 | 69
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278

Disease

Obesity 20 | 678
Cancer 17 | 2,499
diabetes mellitus 17 | 1,728
psoriasis 17 | 6,694
Hyperglycemia 15 | 137
ovarian cancer 14 | 8,520
Carcinoma 13 | 11,493
osteosarcoma 13 | 7,950
invasive ductal carcinoma 12 | 2,951
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
ulcerative colitis 12 | 1,819
Fatty liver disease 11 | 103
breast carcinoma 11 | 1,638
Diabetes Mellitus, Non-Insulin-Dependent 10 | 145
Hyperinsulinism 10 | 133
Polycystic ovary syndrome 10 | 360
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
malignant mesothelioma 10 | 3,232
Alzheimer's disease 9 | 658
Diabetes Mellitus, Experimental 9 | 108
Schizophrenia 9 | 1,160
ductal carcinoma in situ 9 | 1,745
Breast cancer 8 | 3,578
Carcinoma, Hepatocellular 8 | 228
Diabetes Mellitus, Type 2 8 | 142
Hypertension 8 | 396
Insulin Resistance 8 | 72
Liver carcinoma 8 | 240
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Cerebrovascular disease 7 | 238
Depressive disorder 7 | 409
Heart disease 7 | 306
Kidney disease 7 | 430
Lipid metabolism disorder 7 | 114
Rheumatoid arthritis 7 | 1,191
acute quadriplegic myopathy 7 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
pituitary cancer 7 | 1,972
tuberculosis 7 | 2,010
Asthma 6 | 385
Atherosclerosis 6 | 291
Autosomal recessive predisposition 6 | 1,442
Coronary artery disease 6 | 268
Heart failure 6 | 162
Hypertensive disease 6 | 292
Hypoglycemia 6 | 152
Lipodystrophy 6 | 40
Liver disease 6 | 237
Mental Depression 6 | 333
Osteoporosis 6 | 363
Parkinson's disease 6 | 392
Stomach Neoplasms 6 | 300
fibroadenoma 6 | 559
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
Alzheimer Disease 5 | 83
Arthritis 5 | 290
Atopic dermatitis 5 | 952
Crohn Disease 5 | 45
Diabetes Mellitus, Noninsulin-Dependent 5 | 31
Inflammation 5 | 120
Inflammatory bowel disease 5 | 151
Liver Cirrhosis, Experimental 5 | 769
Major Depressive Disorder 5 | 301
Myocardial Infarction 5 | 151
Prostatic Neoplasms 5 | 495
Pulmonary Fibrosis 5 | 106
astrocytoma 5 | 1,146
dermatomyositis 5 | 966
ependymoma 5 | 4,679
group 4 medulloblastoma 5 | 1,855
lung carcinoma 5 | 2,843
primitive neuroectodermal tumor 5 | 3,035
Bipolar Disorder 4 | 666
Chronic Lymphocytic Leukemia 4 | 262
Endometriosis 4 | 540
Hyperalgesia 4 | 83
Hyperandrogenism 4 | 34
Lung disease 4 | 142
Mammary Neoplasms 4 | 425
Mood Disorders 4 | 184
Multiple Sclerosis 4 | 540
Multiple myeloma 4 | 1,332
Myocardial Ischemia 4 | 169
Pick disease 4 | 1,894
Reperfusion Injury 4 | 86
Toxic encephalopathy 4 | 141
Unipolar Depression 4 | 250
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
mucosa-associated lymphoid tissue lymphoma 4 | 484
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 8 | 12,091
Transcription Factor 6 | 1,400
Kinase 3 | 634
Nuclear Receptor 3 | 48
Enzyme 1 | 4,145
Transporter 1 | 473

WikiPathways Pathway

Transcription factor regulatio... 22 | 22
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Nuclear receptor-interacting protein 1 NRIP1 Tbio Non-IDG -2.21323 183.8 155
CCAAT/enhancer-binding protein delta CEBPD Tbio Transcription Factor -2.49029 299.9 179
CCAAT/enhancer-binding protein alpha CEBPA Tbio Transcription Factor -2.94393 846.3 518
Insulin receptor INSR Tclin Kinase -2.50045 306.8 1417
Phosphatidate phosphatase LPIN1 LPIN1 Tbio Enzyme -2.13963 149.5 280
Insulin receptor substrate 2 IRS2 Tbio Non-IDG -2.64133 414.7 227
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Peroxisome proliferator-activated receptor gamma PPARG Tclin Nuclear Receptor -3.96393 9579.5 773