Development Level

Tbio 4 | 10,625
Tclin 2 | 602

Disease

Goiter 5 | 27
Hypothyroidism 5 | 89
Autoimmune thyroiditis 4 | 24
Congenital hypothyroidism 4 | 20
Graves' disease 4 | 25
Hyperthyroidism 4 | 50
Thyroiditis 4 | 25
Thyrotoxicosis 4 | 38
psoriasis 4 | 6,685
Adenoma 3 | 165
Carcinoma 3 | 2,147
Thyroid Dyshormonogenesis 1 3 | 6
osteosarcoma 3 | 7,933
Cancer 2 | 2,346
Celiac disease 2 | 112
Exophthalmos 2 | 16
Graves Disease 2 | 17
Papillary carcinoma 2 | 7
Thyroid Neoplasm 2 | 33
Thyroid adenoma 2 | 9
Thyroid cancer 2 | 25
diabetes mellitus 2 | 1,663
facioscapulohumeral dystrophy 2 | 286
lung carcinoma 2 | 2,844
AUTOIMMUNE THYROID DISEASE, SUSCEPTIBILITY TO, 3 (finding) 1 | 2
Acquired metabolic disease 1 | 267
Acute cystitis 1 | 37
Addison's disease 1 | 29
Adrenal Gland Diseases 1 | 1
Adrenal Gland Neoplasms 1 | 11
Amenorrhea 1 | 60
Amnesia 1 | 17
Anorexia nervosa 1 | 59
Athyreosis 1 | 4
Autoimmune Thyroid Disease, Susceptibility To, 3 1 | 2
Autoimmune thyroid disease 3 1 | 1
Autosomal dominant cerebellar ataxia 1 | 34
Bradycardia 1 | 24
Cardiac arrhythmia 1 | 26
Caries of smooth surface of tooth 1 | 7
Catalepsy 1 | 15
Cholangiocarcinoma 1 | 32
Conduct disorder 1 | 25
Dwarfism 1 | 6
Empty sella syndrome 1 | 6
Endocrine exophthalmos 1 | 1
Eye and adnexa disease 1 | 11
Familial gestational hyperthyroidism 1 | 1
Gastroenteritis 1 | 46
Glioma 1 | 66
HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 1 1 | 2
Hemiplegia 1 | 15
Hyperprolactinemia 1 | 22
Hyperthyroidism, Familial Gestational 1 | 1
Hyperthyroidism, Nonautoimmune 1 | 1
Hyperthyroidism, non-autoimmune 1 | 1
Hypoglycemia 1 | 81
Hypogonadism 1 | 70
Hypoparathyroidism 1 | 29
Hypopituitarism 1 | 36
Hypothalamic disease 1 | 3
Hypothermia, natural 1 | 12
Hypothyroidism, congenital, non-goitrous, 1 1 | 1
Influenza 1 | 142
Intermittent explosive disorder 1 | 4
Iodotyrosyl coupling defect 1 | 1
Kidney Neoplasm 1 | 27
Klinefelter's syndrome 1 | 59
Learning Disorders 1 | 27
Leukemia, Myelocytic, Acute 1 | 113
Lung Neoplasms 1 | 171
Lymphatic Metastasis 1 | 14
Mammary Neoplasms 1 | 410
Melancholia 1 | 12
Melanoma 1 | 261
Narcolepsy 1 | 69
Nelson syndrome 1 | 6
Oligospermia 1 | 30
Orbital disease 1 | 2
Ovarian Diseases 1 | 2
Pain 1 | 70
Parathyroid Adenoma 1 | 11
Personality disorder 1 | 25
Plummer's disease 1 | 7
Pseudohypoparathyroidism 1 | 17
Respiratory Insufficiency 1 | 11
Scalp dermatosis 1 | 1
Seborrheic dermatitis 1 | 19
Serum thyroglobulin level 1 | 1
Stereotypic movement disorder 1 | 6
Thyroid Adenoma, Hyperfunctioning 1 | 1
Thyroid Hypoplasia 1 | 3
Thyroid cancer, follicular 1 | 7
Thyroid dyshormonogenesis 3 1 | 1
Tremor 1 | 8
Uterine Diseases 1 | 1
Vitiligo 1 | 71
adrenal gland cancer 1 | 8
ovarian neoplasm 1 | 97
uncontrolled asthma 1 | 67

Tissue

Blood and immune system 6 | 17,995
Cardiovascular System 6 | 17,958
Digestive Tract 6 | 18,473
Endocrine System 6 | 18,512
Female tissues 6 | 18,647
Liver and Pancreas 6 | 18,136
Male tissues 6 | 17,969
Nervous System 6 | 18,561
Respiratory system 6 | 17,484
Skin and soft tissues 6 | 18,115
Urinary Tract 6 | 18,444

Target Family

Non-IDG 3 | 11,969
Enzyme 1 | 4,146
GPCR 1 | 408
Transporter 1 | 473

WikiPathways Pathway

Thyroxine (Thyroid Hormone) Pr... 6 | 6
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyrotropin receptor TSHR Tclin GPCR -3.01423 1127.2 380
Glycoprotein hormones alpha chain CGA Tbio Non-IDG -2.59383 384.5 708
Thyroglobulin TG Tbio Non-IDG -3.87299 7392.0 874
Sodium/iodide cotransporter SLC5A5 Tbio Transporter -3.00331 927.4 303
Thyroid peroxidase TPO Tclin Enzyme -2.80764 549.8 269
Pro-thyrotropin-releasing hormone TRH Tbio Non-IDG -3.25140 1859.6 98