Development Level

Tbio 46 | 10,625
Tdark 7 | 7,003
Tchem 6 | 1,890
Tclin 2 | 602

IMPC Term

abnormal epididymis morphology 2 | 31
increased circulating sodium l... 2 | 71
abnormal sacral vertebrae morp... 1 | 5
abnormal testis morphology 1 | 30
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased circulating alanine ... 1 | 53
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
hypoactivity 1 | 89
small adrenal glands 1 | 15
small testis 1 | 37

Disease

ovarian cancer 43 | 8,484
glioblastoma 39 | 5,572
lung carcinoma 39 | 2,844
osteosarcoma 36 | 7,933
pilocytic astrocytoma 36 | 3,086
lung cancer 34 | 4,466
interstitial cystitis 32 | 2,299
subependymal giant cell astrocytoma 32 | 2,287
invasive ductal carcinoma 28 | 2,950
pediatric high grade glioma 27 | 2,712
ulcerative colitis 27 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
psoriasis 25 | 6,685
tuberculosis 24 | 1,557
cutaneous lupus erythematosus 23 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
medulloblastoma, large-cell 21 | 6,234
non-small cell lung cancer 21 | 2,798
Cancer 20 | 2,346
primary Sjogren syndrome 20 | 789
astrocytoma 19 | 1,493
malignant mesothelioma 16 | 3,162
pancreatic cancer 16 | 2,300
IGA Glomerulonephritis 15 | 454
adrenocortical carcinoma 15 | 1,427
posterior fossa group A ependymoma 15 | 1,511
Rheumatoid Arthritis 13 | 1,160
diabetes mellitus 13 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
ductal carcinoma in situ 12 | 1,745
group 4 medulloblastoma 12 | 1,875
gastric carcinoma 11 | 832
head and neck cancer and chronic obstructive pulmonary disease 11 | 237
lung adenocarcinoma 11 | 2,713
Duchenne muscular dystrophy 10 | 602
adult high grade glioma 10 | 2,148
atypical teratoid / rhabdoid tumor 10 | 4,369
primary pancreatic ductal adenocarcinoma 10 | 1,271
Breast cancer 9 | 3,094
cystic fibrosis 9 | 1,665
juvenile dermatomyositis 9 | 1,189
mucosa-associated lymphoid tissue lymphoma 9 | 480
breast carcinoma 8 | 1,614
primitive neuroectodermal tumor 8 | 3,031
sarcoidosis 8 | 358
Carcinoma 7 | 2,147
Down syndrome 7 | 548
Kidney disease 7 | 396
active Crohn's disease 7 | 918
group 3 medulloblastoma 7 | 2,254
Lung Neoplasms 6 | 171
Peripheral Neuropathy 6 | 303
acute quadriplegic myopathy 6 | 1,157
esophageal adenocarcinoma 6 | 737
inflammatory breast cancer 6 | 404
nephrosclerosis 6 | 329
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
periodontitis 6 | 269
sonic hedgehog group medulloblastoma 6 | 1,482
spina bifida 6 | 1,064
Becker muscular dystrophy 5 | 187
Dermatitis 5 | 107
Hypersensitivity reaction type II disease 5 | 235
Multiple Sclerosis 5 | 498
Obesity 5 | 616
acute myeloid leukemia 5 | 780
aldosterone-producing adenoma 5 | 664
chronic lymphosyte leukemia 5 | 232
nasopharyngeal carcinoma 5 | 1,056
Adenocarcinoma 4 | 115
Asthma 4 | 349
Atherosclerosis 4 | 275
Calcinosis 4 | 62
Celiac disease 4 | 112
Chronic Lymphocytic Leukemia 4 | 242
Colorectal Neoplasms 4 | 217
Dermatitis, Allergic Contact 4 | 66
Heart valve disease 4 | 24
Hypersensitivity 4 | 63
Leukocyte adhesion deficiency 4 | 15
Mammary Neoplasms 4 | 410
Multiple myeloma 4 | 1,327
Neoplasm Metastasis 4 | 138
Osteoporosis 4 | 257
Pneumonia 4 | 133
Vascular disease 4 | 281
Waldenstrons macroglobulinemia 4 | 765
active ulcerative colitis 4 | 477
colon cancer 4 | 1,475
head and neck cancer 4 | 270
oligodendroglioma 4 | 2,849
systemic lupus erythematosus 4 | 156
tuberculosis and treatment for 6 months 4 | 686
Prostatic Neoplasms 3 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
dermatomyositis 3 | 933
ependymoma 3 | 2,514
hepatocellular carcinoma 3 | 532
pancreatic carcinoma 3 | 567
pituitary cancer 3 | 1,972

Tissue

Blood and immune system 61 | 17,995
Cardiovascular System 61 | 17,958
Digestive Tract 61 | 18,473
Endocrine System 61 | 18,512
Female tissues 61 | 18,647
Liver and Pancreas 61 | 18,136
Male tissues 61 | 17,969
Nervous System 61 | 18,561
Respiratory system 61 | 17,484
Skin and soft tissues 61 | 18,115
Urinary Tract 61 | 18,444

Target Family

Non-IDG 40 | 11,971
Enzyme 8 | 4,146
Transcription Factor 7 | 1,400
Transporter 3 | 473
Kinase 2 | 634
Ion Channel 1 | 341

WikiPathways Pathway

TYROBP Causal Network 61 | 61
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
SH2B adapter protein 3 SH2B3 Tbio Non-IDG -2.46631 317.6 137
Complement C1q subcomponent subunit C C1QC Tbio Non-IDG -1.27032 17.5 141
Leukocyte antigen CD37 CD37 Tbio Non-IDG -1.91433 88.8 205
Integrin alpha-M ITGAM Tchem Non-IDG -3.58843 3795.9 1805
Multidrug resistance-associated protein 4 ABCC4 Tbio Transporter -2.50986 316.0 288
Cyclic AMP-responsive element-binding protein 3-like protein 2 CREB3L2 Tbio Transcription Factor -2.46118 296.9 147
TYRO protein tyrosine kinase-binding protein TYROBP Tbio Enzyme -2.28112 203.5 188
Y+L amino acid transporter 1 SLC7A7 Tbio Transporter -1.67215 51.9 32
Negative regulator of reactive oxygen species NRROS Tbio Non-IDG -0.73373 6.02 73
Runt-related transcription factor 3 RUNX3 Tbio Transcription Factor -2.63682 492.3 375