Development Level

Tbio 15 | 11,651
Tchem 4 | 1,388
Tclin 2 | 612

IMPC Phenotype

enlarged heart 3 | 210
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
cataract 2 | 92
decreased circulating insulin ... 2 | 76
decreased mean corpuscular vol... 2 | 79
hyperactivity 2 | 148
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
abnormal epididymis morphology 1 | 42
abnormal lung morphology 1 | 26
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hypoactivity 1 | 132
preweaning lethality, incomple... 1 | 499
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Cancer 18 | 2,499
ovarian cancer 14 | 8,520
Carcinoma 13 | 11,493
lung cancer 12 | 4,740
osteosarcoma 12 | 7,950
atypical teratoid / rhabdoid tumor 11 | 5,112
medulloblastoma, large-cell 11 | 6,241
psoriasis 11 | 6,694
glioblastoma 10 | 5,792
malignant mesothelioma 10 | 3,232
pancreatic cancer 10 | 2,398
Breast Neoplasms 9 | 445
Prostatic Neoplasms 9 | 495
Lymphoid leukemia 8 | 160
Mammary Neoplasms 8 | 425
Pancreatic Neoplasm 8 | 85
group 3 medulloblastoma 8 | 4,104
Breast cancer 7 | 3,578
Colonic Neoplasms 7 | 142
Immune system cancer 7 | 140
Pancreatic Neoplasms 7 | 85
Stomach Neoplasms 7 | 300
adrenocortical carcinoma 7 | 1,428
ependymoma 7 | 4,679
juvenile dermatomyositis 7 | 1,187
oligodendroglioma 7 | 2,850
tuberculosis 7 | 2,010
Adenocarcinoma 6 | 122
Adenoma 6 | 167
Carcinoma, Hepatocellular 6 | 228
Esophageal Neoplasms 6 | 69
Liver carcinoma 6 | 240
Lung Neoplasms 6 | 232
Lymphoma 6 | 81
Melanoma 6 | 711
acute quadriplegic myopathy 6 | 1,158
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
primitive neuroectodermal tumor 6 | 3,035
Astrocytoma, Pilocytic 5 | 3,081
Bladder Neoplasm 5 | 112
Carcinoma, Squamous Cell 5 | 110
Cell Transformation, Neoplastic 5 | 97
Chronic Lymphocytic Leukemia 5 | 262
Liver neoplasms 5 | 130
Neoplastic Cell Transformation 5 | 89
Schizophrenia 5 | 1,160
Skin cancer 5 | 469
Squamous cell carcinoma 5 | 129
Urinary Bladder Neoplasms 5 | 114
Vascular disease 5 | 319
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
hepatocellular carcinoma 5 | 547
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
Adenocarcinoma of lung (disorder) 4 | 60
Amyotrophic lateral sclerosis 4 | 451
Bipolar Disorder 4 | 666
Carcinoma, Non-Small-Cell Lung 4 | 107
Cleft Palate 4 | 271
Colorectal Neoplasms 4 | 243
Fatigue 4 | 182
HIV Infections 4 | 102
Infertility, Male 4 | 46
Leukemia, Lymphocytic, Chronic, B-Cell 4 | 34
Li-Fraumeni syndrome 4 | 13
Liver Neoplasms, Experimental 4 | 59
Liver cancer 4 | 604
Lymphoma, T-Cell, Cutaneous 4 | 22
Male infertility 4 | 206
Mesothelioma, Malignant 4 | 105
Mouth Neoplasms 4 | 55
Multiple myeloma 4 | 1,332
Myocardial Infarction 4 | 151
Neoplasm Metastasis 4 | 168
Ovarian Neoplasms 4 | 102
Papilloma 4 | 44
Polycystic ovary syndrome 4 | 360
Splenomegaly 4 | 190
Stomach cancer 4 | 30
acute T cell leukemia 4 | 17
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
gastric cancer 4 | 459
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
non-small cell lung carcinoma 4 | 317
ovarian neoplasm 4 | 99
primary pancreatic ductal adenocarcinoma 4 | 1,109
Alzheimer's disease 3 | 658
Epilepsy 3 | 792
Leukemia 3 | 104
Seizures 3 | 596
astrocytoma 3 | 1,146
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064

Tissue

Endocrine System 19 | 18,159
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Blood and immune system 18 | 16,909
Digestive Tract 18 | 17,369
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 11 | 12,091
Transcription Factor 5 | 1,400
Enzyme 3 | 4,145
Kinase 2 | 634

WikiPathways Pathway

TP53 Network 21 | 21
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981
Small ubiquitin-related modifier 1 SUMO1 Tbio Non-IDG -2.72599 482.7 786
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Tumor necrosis factor ligand superfamily member 10 TNFSF10 Tbio Non-IDG -2.87006 661.9 949
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.72848 9058.6 1063
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.11278 12358.0 2705
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.41690 2313.9 1252
Tyrosine-protein kinase ABL1 ABL1 Tclin Kinase -3.51854 3418.5 1661
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43737 3042.8 1509