Development Level

Tbio 3 | 11,445
Tchem 2 | 1,598

Disease

medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
psoriasis 4 | 6,694
tuberculosis 4 | 2,010
Carcinoma 3 | 11,493
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Carcinoma, Squamous Cell 2 | 110
Colorectal Neoplasms 2 | 243
Hepatomegaly 2 | 285
Lung Neoplasms 2 | 232
Obesity 2 | 678
Precursor Cell Lymphoblastic Leukemia Lymphoma 2 | 43
Precursor Cell Lymphoblastic Leukemia-Lymphoma 2 | 49
Schizophrenia 2 | 1,160
Squamous cell carcinoma 2 | 129
adrenocortical carcinoma 2 | 1,428
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
Adenoma 1 | 167
Adverse reaction to drug 1 | 61
Amelogenesis imperfecta type 1B 1 | 4
Atopic dermatitis 1 | 952
Atrophic 1 | 10
Atrophy 1 | 10
Autoimmune hepatitis 1 | 11
Axenfeld-Rieger syndrome 1 | 14
Blindness 1 | 88
Breast Neoplasms 1 | 445
COPD 1 | 118
Cardiomegaly 1 | 116
Cardiovascular system disease 1 | 246
Chemical and Drug Induced Liver Injury 1 | 195
Cholestasis 1 | 155
Clouding of corneal stroma 1 | 50
Corneal Opacity 1 | 53
Corneal disease 1 | 31
Dermatitis, Contact 1 | 71
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Drug-Related Side Effects and Adverse Reactions 1 | 62
Essential Hypertension 1 | 94
Fatty Liver 1 | 70
GLAUCOMA 1, OPEN ANGLE, A 1 | 3
GLAUCOMA 3, PRIMARY CONGENITAL, A 1 | 4
Gaucher disease type 1 1 | 180
Glaucoma of childhood 1 | 2
Globe disease 1 | 67
Globe of eye large 1 | 20
Glucose Intolerance 1 | 19
Growth Disorders 1 | 35
Hearing Loss 1 | 17
Homocystinuria 1 | 21
Hydrophthalmos 1 | 19
Irido-corneo-trabecular dysgenesis (disorder) 1 | 10
Liver Cirrhosis 1 | 181
Liver Cirrhosis, Experimental 1 | 769
Liver Neoplasms, Experimental 1 | 59
Liver disease 1 | 237
Liver diseases 1 | 87
Mammary Neoplasms 1 | 425
Mastitis 1 | 48
Melanoma 1 | 711
Mouth Neoplasms 1 | 55
Neural Tube Defects 1 | 31
Non-alcoholic Fatty Liver Disease 1 | 42
Nonsyndromic deafness 1 | 142
Occult macular dystrophy 1 | 7
Ovarian Neoplasms 1 | 102
Pigment dispersion syndrome 1 | 11
Polycystic ovary syndrome 1 | 360
Primary open angle glaucoma juvenile onset 1 1 | 2
Staphyloenterotoxemia 1 | 18
Substance-Related Disorders 1 | 115
breast carcinoma 1 | 1,638
fascioscapulohumeral muscular dystrophy 1 | 100
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hearing impairment 1 | 199
inflammatory breast cancer 1 | 286
limb girdle muscular dystrophy 2B 1 | 40
ovarian neoplasm 1 | 99
posterior fossa group A ependymoma 1 | 468
primary congenital glaucoma 1 | 5
primary open angle glaucoma 1 | 16
pulmonary arterial hypertension 1 | 75
substance-related disorder 1 | 162

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 3 | 4,145
Non-IDG 2 | 12,091

WikiPathways Pathway

Sulindac Metabolic Pathway 5 | 5
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial peptide methionine sulfoxide reductase MSRA Tbio Enzyme -1.92325 88.1 167
Cytochrome P450 1B1 CYP1B1 Tchem Non-IDG -2.93702 904.4 260
Methionine-R-sulfoxide reductase B2, mitochondrial MSRB2 Tbio Enzyme -1.84856 71.5 120
Methionine-R-sulfoxide reductase B3 MSRB3 Tbio Enzyme -1.27275 18.8 55
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.33208 2096.3 492