Development Level

Tchem 4 | 1,890
Tbio 1 | 10,625

Disease

medulloblastoma, large-cell 5 | 6,234
osteosarcoma 5 | 7,933
ovarian cancer 5 | 8,484
psoriasis 4 | 6,685
tuberculosis 4 | 1,557
group 4 medulloblastoma 3 | 1,875
lung adenocarcinoma 3 | 2,713
malignant mesothelioma 3 | 3,162
pancreatic cancer 3 | 2,300
primary pancreatic ductal adenocarcinoma 3 | 1,271
Breast cancer 2 | 3,094
Cancer 2 | 2,346
Colorectal Neoplasms 2 | 217
Lung Neoplasms 2 | 171
Precursor Cell Lymphoblastic Leukemia Lymphoma 2 | 42
Schizophrenia 2 | 501
Squamous cell carcinoma 2 | 94
adrenocortical carcinoma 2 | 1,427
cystic fibrosis 2 | 1,665
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung carcinoma 2 | 2,844
non-small cell lung cancer 2 | 2,798
pancreatic carcinoma 2 | 567
posterior fossa group A ependymoma 2 | 1,511
Adenoma 1 | 165
Adverse reaction to drug 1 | 54
Aniridia 1 | 26
Atopic dermatitis 1 | 944
Atrophic 1 | 10
Autoimmune hepatitis 1 | 13
Autoimmune polyendocrine syndrome 1 | 6
Axenfeld-Rieger syndrome 1 | 11
Bipolar Disorder 1 | 266
Blindness 1 | 84
COPD 1 | 113
Cardiomegaly 1 | 66
Cardiovascular system disease 1 | 194
Chronic Obstructive Airway Disease 1 | 47
Contact Dermatitis 1 | 80
Corneal disease 1 | 32
Diabetes Mellitus, Non-Insulin-Dependent 1 | 157
Essential Hypertension 1 | 82
GLAUCOMA 1, OPEN ANGLE, A 1 | 3
GLAUCOMA 3, PRIMARY CONGENITAL, A 1 | 2
Gaucher disease type 1 1 | 171
Glaucoma 1 | 134
Globe disease 1 | 57
Growth Disorders 1 | 33
Hepatomegaly 1 | 10
Homocystinuria 1 | 23
Irido-corneo-trabecular dysgenesis (disorder) 1 | 6
Liver Cirrhosis, Experimental 1 | 108
Liver Neoplasms, Experimental 1 | 48
Liver disease 1 | 219
Liver diseases 1 | 66
Lung Injury 1 | 20
Mammary Neoplasms 1 | 410
Mastitis 1 | 48
Melanoma 1 | 261
Methemoglobinemia 1 | 17
Mouth Neoplasms 1 | 42
Myotonia congenita 1 | 10
Neural Tube Defects 1 | 27
Newcastle disease 1 | 13
Nonsyndromic deafness 1 | 121
Occult macular dystrophy 1 | 7
Peripheral Neuropathy 1 | 303
Pick disease 1 | 1,893
Polycystic Ovary Syndrome 1 | 332
Prostatic Neoplasms 1 | 471
Staphyloenterotoxemia 1 | 20
Substance-Related Disorders 1 | 114
acute myeloid leukemia 1 | 780
acute quadriplegic myopathy 1 | 1,157
adult high grade glioma 1 | 2,148
astrocytoma 1 | 1,493
breast carcinoma 1 | 1,614
dermatomyositis 1 | 933
diabetes mellitus 1 | 1,663
fascioscapulohumeral muscular dystrophy 1 | 100
hearing impairment 1 | 40
hepatocellular carcinoma 1 | 532
inflammatory breast cancer 1 | 404
juvenile dermatomyositis 1 | 1,189
limb girdle muscular dystrophy 2B 1 | 74
mucosa-associated lymphoid tissue lymphoma 1 | 480
nephrosclerosis 1 | 329
non diabetic and post-ischemic heart failure 1 | 200
oligodendroglioma 1 | 2,849
ovarian neoplasm 1 | 97
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
pilocytic astrocytoma 1 | 3,086
pituitary cancer 1 | 1,972
pulmonary arterial hypertension 1 | 36
spina bifida 1 | 1,064
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 105

Tissue

Blood and immune system 5 | 17,995
Cardiovascular System 5 | 17,958
Digestive Tract 5 | 18,473
Endocrine System 5 | 18,512
Female tissues 5 | 18,647
Liver and Pancreas 5 | 18,136
Male tissues 5 | 17,969
Nervous System 5 | 18,561
Respiratory system 5 | 17,484
Skin and soft tissues 5 | 18,115
Urinary Tract 5 | 18,444

Target Family

Enzyme 3 | 4,146
Non-IDG 2 | 11,971

WikiPathways Pathway

Sulindac Metabolic Pathway 5 | 5
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial peptide methionine sulfoxide reductase MSRA Tbio Enzyme -1.89175 84.7 154
Methionine-R-sulfoxide reductase B2, mitochondrial MSRB2 Tchem Enzyme -1.86129 72.9 104
Methionine-R-sulfoxide reductase B3 MSRB3 Tchem Enzyme -1.19491 17.2 26
Cytochrome P450 1B1 CYP1B1 Tchem Non-IDG -2.90618 863.4 217
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.30248 2022.5 420