Development Level

Tbio 78 | 10,625
Tchem 44 | 1,890
Tclin 35 | 602

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, incomple... 6 | 260
decreased bone mineral content 4 | 157
preweaning lethality, complete... 4 | 633
abnormal bone structure 3 | 131
decreased body length 3 | 108
embryonic lethality prior to t... 3 | 187
hyperactivity 3 | 108
increased bone mineral density 3 | 52
increased circulating alkaline... 3 | 119
increased lean body mass 3 | 107
abnormal behavior 2 | 226
abnormal behavioral response t... 2 | 52
abnormal epididymis morphology 2 | 31
abnormal head morphology 2 | 10
abnormal startle reflex 2 | 14
decreased body weight 2 | 174
decreased circulating glycerol... 2 | 19
decreased circulating total pr... 2 | 41
decreased fasted circulating g... 2 | 49
decreased hemoglobin content 2 | 53
decreased lean body mass 2 | 195
decreased mean corpuscular hem... 2 | 19
decreased total body fat amoun... 2 | 186
enlarged heart 2 | 111
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased leukocyte cell numbe... 2 | 37
increased startle reflex 2 | 38
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal ovary morphology 1 | 3
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal outer nuclear... 1 | 5
abnormal rib morphology 1 | 28
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spinal cord morpholog... 1 | 8
abnormal thoracic vertebrae mo... 1 | 16
abnormal urinary bladder morph... 1 | 2
aorta dilation 1 | 3
convulsive seizures 1 | 11
decreased B cell number 1 | 30
decreased Ly6C low monocyte nu... 1 | 23
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased lactate dehydrogenas... 1 | 14
decreased mature B cell number 1 | 25
decreased mean platelet volume 1 | 12
decreased prepulse inhibition 1 | 52
decreased threshold for audito... 1 | 32
enlarged lymph nodes 1 | 27
female infertility 1 | 34
hydrops fetalis 1 | 22
impaired righting response 1 | 19
increased Ly6C high monocyte n... 1 | 12
increased NK T cell number 1 | 11
increased body length 1 | 20
increased bone mineral content 1 | 92
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating free fat... 1 | 17
increased circulating fructosa... 1 | 11
increased circulating phosphat... 1 | 24
increased circulating serum al... 1 | 25
increased effector memory CD4-... 1 | 15
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
increased vertical activity 1 | 18
male infertility 1 | 62
oligodactyly 1 | 14
short tibia 1 | 82
shortened head 1 | 2
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

medulloblastoma, large-cell 86 | 6,234
psoriasis 79 | 6,685
glioblastoma 78 | 5,572
osteosarcoma 75 | 7,933
ovarian cancer 75 | 8,484
Cancer 66 | 2,346
lung cancer 64 | 4,466
atypical teratoid / rhabdoid tumor 62 | 4,369
primitive neuroectodermal tumor 53 | 3,031
oligodendroglioma 52 | 2,849
pediatric high grade glioma 49 | 2,712
pilocytic astrocytoma 47 | 3,086
lung carcinoma 40 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,289
lung adenocarcinoma 38 | 2,713
ulcerative colitis 38 | 2,087
group 4 medulloblastoma 37 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,956
pituitary cancer 37 | 1,972
Breast cancer 36 | 3,094
ependymoma 36 | 2,514
malignant mesothelioma 36 | 3,162
Parkinson's disease 34 | 364
Schizophrenia 34 | 501
astrocytoma 33 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,988
subependymal giant cell astrocytoma 33 | 2,287
colon cancer 32 | 1,475
diabetes mellitus 32 | 1,663
invasive ductal carcinoma 32 | 2,950
pancreatic cancer 32 | 2,300
interstitial cystitis 31 | 2,299
non-small cell lung cancer 30 | 2,798
Alzheimer's disease 29 | 644
Autistic Disorder 27 | 320
Obesity 27 | 616
adult high grade glioma 26 | 2,148
astrocytic glioma 25 | 2,241
cystic fibrosis 24 | 1,665
ductal carcinoma in situ 24 | 1,745
posterior fossa group A ependymoma 24 | 1,511
Carcinoma 23 | 2,147
Pick disease 23 | 1,893
breast carcinoma 23 | 1,614
Bipolar Disorder 22 | 266
Rheumatoid Arthritis 22 | 1,160
Epilepsy 21 | 346
Sudden infant death syndrome 21 | 33
group 3 medulloblastoma 21 | 2,254
medulloblastoma 21 | 1,524
primary pancreatic ductal adenocarcinoma 21 | 1,271
Kidney disease 19 | 396
Major Depressive Disorder 19 | 106
tuberculosis 19 | 1,557
Asthma 18 | 349
Cerebrovascular disease 18 | 231
Hypertension 18 | 287
Multiple myeloma 18 | 1,327
acute quadriplegic myopathy 18 | 1,157
Diarrhea 17 | 155
Down syndrome 17 | 548
Heart disease 17 | 279
Inflammatory bowel disease 17 | 142
Intellectual disability 17 | 573
Mammary Neoplasms 17 | 410
Toxic encephalopathy 17 | 131
adrenocortical carcinoma 17 | 1,427
atypical teratoid/rhabdoid tumor 17 | 1,095
Alcohol dependence 16 | 107
Dementia 16 | 129
Prostatic Neoplasms 16 | 471
Status Epilepticus 16 | 85
Waldenstrons macroglobulinemia 16 | 765
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
Attention deficit hyperactivity disorder 15 | 156
Hyperglycemia 15 | 120
Inflammation 15 | 109
cutaneous lupus erythematosus 15 | 1,056
gastric carcinoma 15 | 832
posterior fossa group B ependymoma 15 | 1,530
Arthritis 14 | 248
Brain Ischemia 14 | 87
Diabetes Mellitus, Experimental 14 | 106
Diabetes Mellitus, Non-Insulin-Dependent 14 | 157
Endometriosis 14 | 535
Multiple Sclerosis 14 | 498
Vascular disease 14 | 281
sonic hedgehog group medulloblastoma 14 | 1,482
Amyotrophic Lateral Sclerosis 13 | 431
Brain disease 13 | 83
Hypersensitivity reaction type II disease 13 | 235
Lung Neoplasms 13 | 171
Seizures 13 | 95
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
dermatomyositis 13 | 933
Cocaine-Related Disorders 12 | 88
Huntington's disease 12 | 72
Lung disease 12 | 132
Stomach Neoplasms 12 | 282
aldosterone-producing adenoma 12 | 664

Tissue

Endocrine System 157 | 18,512
Female tissues 157 | 18,647
Nervous System 157 | 18,561
Urinary Tract 157 | 18,444
Cardiovascular System 156 | 17,958
Digestive Tract 156 | 18,473
Liver and Pancreas 155 | 18,136
Skin and soft tissues 155 | 18,115
Blood and immune system 153 | 17,995
Male tissues 153 | 17,969
Respiratory system 149 | 17,484

Target Family

Transcription Factor 47 | 1,400
Non-IDG 45 | 11,971
Enzyme 23 | 4,146
Ion Channel 14 | 341
GPCR 9 | 406
Kinase 5 | 634
Nuclear Receptor 5 | 48
Transporter 5 | 473
Epigenetic 4 | 242

WikiPathways Pathway

Sudden Infant Death Syndrome (... 157 | 157
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Endoplasmin HSP90B1 Tchem Non-IDG -2.72785 604.5 748
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Transcription factor E2-alpha TCF3 Tbio Transcription Factor -2.76637 577.9 373
Trifunctional enzyme subunit alpha, mitochondrial HADHA Tbio Non-IDG -2.96515 948.2 132
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952