Development Level

Tbio 29 | 11,445
Tclin 7 | 613
Tchem 6 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
hydrometra 2 | 53
increased circulating alkaline... 2 | 122
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal seminal vesicle morph... 1 | 114
abnormal tail movements 1 | 12
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
cataract 1 | 92
decreased body length 1 | 101
decreased circulating calcium ... 1 | 36
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged adrenal glands 1 | 3
enlarged epididymis 1 | 31
enlarged gallbladder 1 | 2
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 38 | 11,493
glioblastoma 30 | 5,792
medulloblastoma, large-cell 30 | 6,241
atypical teratoid / rhabdoid tumor 29 | 5,112
adult high grade glioma 25 | 3,801
ependymoma 24 | 4,679
ovarian cancer 24 | 8,520
oligodendroglioma 23 | 2,850
psoriasis 23 | 6,694
Astrocytoma, Pilocytic 22 | 3,081
group 3 medulloblastoma 22 | 4,104
astrocytic glioma 21 | 2,597
osteosarcoma 20 | 7,950
primitive neuroectodermal tumor 19 | 3,035
pituitary cancer 18 | 1,972
lung cancer 16 | 4,740
Kidney cancer 15 | 2,613
lung carcinoma 15 | 2,843
malignant mesothelioma 15 | 3,232
subependymal giant cell astrocytoma 15 | 2,287
invasive ductal carcinoma 14 | 2,951
lung adenocarcinoma 12 | 2,716
Breast cancer 11 | 3,578
Intellectual disability 11 | 1,016
Pick disease 11 | 1,894
interstitial cystitis 10 | 2,312
Bipolar Disorder 9 | 666
Epilepsy 9 | 792
Schizophrenia 9 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Cancer 8 | 2,499
Melanoma 8 | 711
ductal carcinoma in situ 8 | 1,745
non-small cell lung cancer 8 | 2,890
Alzheimer's disease 7 | 658
Autistic Disorder 7 | 364
Dull intelligence 7 | 645
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
colon cancer 6 | 1,478
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Alcoholic Intoxication, Chronic 5 | 289
Autosomal recessive predisposition 5 | 1,442
Cognitive delay 5 | 608
Duchenne muscular dystrophy 5 | 601
Global developmental delay 5 | 608
Mental and motor retardation 5 | 608
Muscle hypotonia 5 | 571
Seizures 5 | 596
astrocytoma 5 | 1,146
pancreatic cancer 5 | 2,398
pediatric high grade glioma 5 | 1,064
Alcoholism 4 | 45
Gaucher disease type 1 4 | 180
Hyperalgesia 4 | 83
Parkinson's disease 4 | 392
Skin cancer 4 | 469
Small head 4 | 374
Status Epilepticus 4 | 98
Tonic - clonic seizures 4 | 44
adrenocortical carcinoma 4 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cutaneous lupus erythematosus 4 | 1,057
dermatomyositis 4 | 966
gastric carcinoma 4 | 807
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary pancreatic ductal adenocarcinoma 4 | 1,109
Byzanthine arch palate 3 | 194
Cocaine-Related Disorders 3 | 92
Depressive disorder 3 | 409
Electroencephalogram abnormal 3 | 101
Hyperreflexia 3 | 209
Hypoplastic mandible condyle 3 | 275
Long philtrum 3 | 137
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Muscle Spasticity 3 | 195
Rheumatoid arthritis 3 | 1,191
Vascular disease 3 | 319
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
gastric cancer 3 | 459
juvenile dermatomyositis 3 | 1,187
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074
substance-related disorder 3 | 162

Tissue

Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Skin and soft tissues 42 | 17,230
Blood and immune system 41 | 16,909
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Female tissues 40 | 17,400
Respiratory system 39 | 16,393
Urinary Tract 38 | 16,678
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 25 | 12,091
Ion Channel 7 | 344
Kinase 5 | 634
Enzyme 3 | 4,145
GPCR 1 | 408
Transporter 1 | 473

WikiPathways Pathway

Splicing factor NOVA regulated... 42 | 42
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calsyntenin-1 CLSTN1 Tbio Non-IDG -1.09760 15.0 131
Telomeric repeat-binding factor 2-interacting protein 1 TERF2IP Tchem Non-IDG -0.75509 5.75 308
Caveolin-2 CAV2 Tbio Non-IDG -2.43448 254.2 294
Microtubule-associated protein 4 MAP4 Tbio Non-IDG -2.27689 185.8 253
Ankyrin-3 ANK3 Tbio Non-IDG -2.25280 172.9 170
Calcium-activated potassium channel subunit alpha-1 KCNMA1 Tclin Ion Channel -3.09649 1238.5 222
Plasma membrane calcium-transporting ATPase 1 ATP2B1 Tbio Transporter -2.01694 100.0 110
Cadherin-2 CDH2 Tbio Non-IDG -3.19431 1382.9 993
Gamma-aminobutyric acid type B receptor subunit 2 GABBR2 Tclin GPCR -1.97367 92.4 395