Development Level

Tbio 6 | 11,445
Tclin 5 | 613
Tchem 2 | 1,598

IMPC Phenotype

abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
decreased body weight 1 | 161
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27

Disease

Carcinoma 11 | 11,493
Schizophrenia 8 | 1,160
glioblastoma 8 | 5,792
Major Depressive Disorder 7 | 301
Mental Depression 7 | 333
Unipolar Depression 7 | 250
medulloblastoma, large-cell 7 | 6,241
ovarian cancer 7 | 8,520
Alcoholic Intoxication, Chronic 6 | 289
Astrocytoma, Pilocytic 6 | 3,081
Bipolar Disorder 6 | 666
Cocaine-Related Disorders 6 | 92
Depressive disorder 6 | 409
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
primitive neuroectodermal tumor 6 | 3,035
Alcohol dependence 5 | 107
Alzheimer's disease 5 | 658
Generalized anxiety disorder 5 | 29
Mood Disorders 5 | 184
Panic disorder 5 | 61
Parkinson's disease 5 | 392
Substance abuse 5 | 59
astrocytic glioma 5 | 2,597
atypical teratoid / rhabdoid tumor 5 | 5,112
group 4 medulloblastoma 5 | 1,855
lung carcinoma 5 | 2,843
oligodendroglioma 5 | 2,850
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
Attention deficit hyperactivity disorder 4 | 278
Autistic Disorder 4 | 364
Cancer 4 | 2,499
Down syndrome 4 | 499
Epilepsy 4 | 792
Hyperactive behavior 4 | 91
Hyperkinesis 4 | 32
Kidney cancer 4 | 2,613
Migraine 4 | 83
Obesity 4 | 678
Rheumatoid arthritis 4 | 1,191
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
pituitary cancer 4 | 1,972
post-traumatic stress disorder 4 | 40
Alcohol abuse 3 | 50
Amnestic disorder 3 | 35
Anhedonia 3 | 27
Anxiety Disorders 3 | 38
Breast cancer 3 | 3,578
Fever 3 | 138
Hyperalgesia 3 | 83
Irritable bowel syndrome 3 | 60
Liver Cirrhosis, Experimental 3 | 769
Osteoporosis 3 | 363
Pain agnosia 3 | 104
Personality disorder 3 | 25
Pick disease 3 | 1,894
Seizures 3 | 596
Substance Withdrawal Syndrome 3 | 55
Waldenstrons macroglobulinemia 3 | 765
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
group 3 medulloblastoma 3 | 4,104
lung adenocarcinoma 3 | 2,716
posterior fossa group A ependymoma 3 | 468
subependymal giant cell astrocytoma 3 | 2,287
Acromegaly 2 | 51
Alzheimer Disease 2 | 83
Anorexia 2 | 43
Anorexia nervosa 2 | 80
Atopic dermatitis 2 | 952
Bipolar affective disorder, current episode manic 2 | 13
Bipolar disorder in remission 2 | 19
Brain Injuries 2 | 65
Drug psychosis 2 | 7
Hypertension 2 | 396
Hypoglycemia 2 | 152
Melancholia 2 | 10
Migraine Disorders 2 | 76
Mixed bipolar I disorder 2 | 9
Movement Disorders 2 | 55
Parkinsonism 2 | 18
Premature ejaculation 2 | 16
Psychotic Disorders 2 | 151
Schizoaffective Disorder 2 | 55
Status Epilepticus 2 | 98
Stomach Neoplasms 2 | 300
Sudden infant death syndrome 2 | 32
Toxic encephalopathy 2 | 141
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
chronic kidney disease 2 | 90
diabetes mellitus 2 | 1,728
obsessive-compulsive disorder 2 | 61
sarcoidosis 2 | 370
severe Alzheimer's disease 2 | 47

Tissue

Nervous System 13 | 16,725
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Digestive Tract 11 | 17,369
Male tissues 11 | 17,142
Skin and soft tissues 11 | 17,230
Liver and Pancreas 10 | 16,750
Respiratory system 10 | 16,393
Urinary Tract 10 | 16,678
Blood and immune system 9 | 16,909
Cardiovascular System 7 | 15,192

Target Family

GPCR 4 | 408
Enzyme 3 | 4,145
Non-IDG 3 | 12,091
Ion Channel 1 | 344
Kinase 1 | 634
Transcription Factor 1 | 1,400

WikiPathways Pathway

Serotonin and anxiety-related ... 13 | 13
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
5-hydroxytryptamine receptor 1A HTR1A Tclin GPCR -3.67718 4891.4 254
5-hydroxytryptamine receptor 2A HTR2A Tclin GPCR -3.33563 2152.8 231
Neuroligin-1 NLGN1 Tbio Enzyme -1.96626 95.1 225
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 PLCD4 Tbio Enzyme -1.09921 11.4 47
Proto-oncogene c-Fos FOS Tbio Transcription Factor -4.14231 13598.8 1058
5-hydroxytryptamine receptor 2C HTR2C Tclin GPCR -3.08158 1199.3 336
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA Tchem Enzyme -3.00226 997.7 359
Activity-regulated cytoskeleton-associated protein ARC Tbio Non-IDG -2.30664 188.9 176
Glutamate receptor ionotropic, NMDA 2D GRIN2D Tclin Ion Channel -2.11112 128.4 110