Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal coat appearance 1 | 31
impaired glucose tolerance 1 | 75
increased fasted circulating g... 1 | 76

Disease

Carcinoma 9 | 11,493
Breast cancer 7 | 3,578
ovarian cancer 7 | 8,520
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
adult high grade glioma 4 | 3,801
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
Atopic dermatitis 3 | 952
Cancer 3 | 2,499
Cardiomegaly 3 | 116
Heart disease 3 | 306
Myocardial Ischemia 3 | 169
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Abnormal nasal morphology 2 | 16
Astrocytoma, Pilocytic 2 | 3,081
Broad forehead 2 | 59
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Congenital heart disease 2 | 93
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Dilated ventricles (finding) 2 | 121
Epilepsy 2 | 792
Global developmental delay 2 | 608
High forehead 2 | 102
Intellectual disability 2 | 1,016
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
Myocardial Infarction 2 | 151
Orbital separation excessive 2 | 244
Parkinson's disease 2 | 392
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Severe mental retardation (I.Q. 20-34) 2 | 99
Tall forehead 2 | 102
Vascular disease 2 | 319
Ventricular Septal Defects 2 | 119
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
chronic lymphosyte leukemia 2 | 204
gastric cancer 2 | 459
interstitial lung disease 2 | 298
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
pancreatic cancer 2 | 2,398
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
Autism Spectrum Disorders 1 | 75
Brachydactyly 1 | 156
Congenital Heart Defects 1 | 58
Conotruncal Heart Malformations 1 | 10
Discordant ventriculoarterial connection 1 | 17
Fatigue 1 | 182
Fibrosis 1 | 44
HIV Infections 1 | 102
Heart Defects, Congenital 1 | 37
Holt-Oram syndrome 1 | 12
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Mitral valve insufficiency 1 | 49
Muscle Weakness 1 | 170
Neuronal ceroid lipofuscinosis 2 1 | 17
Nonorganic psychosis 1 | 84
Ovarian Neoplasms 1 | 102
Pitt-Hopkins syndrome 1 | 20
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Progressive mental retardation 1 | 37
Stereotyped Behavior 1 | 37
Stereotypic Movement Disorder 1 | 42
Tetralogy of Fallot 1 | 63
chronic kidney disease 1 | 90
fascioscapulohumeral muscular dystrophy 1 | 100
ovarian neoplasm 1 | 99
ventricular septal defect 1 | 20

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Female tissues 10 | 17,400
Urinary Tract 10 | 16,678
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230

Target Family

Transcription Factor 7 | 1,400
Non-IDG 2 | 12,091
Kinase 1 | 634

WikiPathways Pathway

SRF and miRs in Smooth Muscle ... 10 | 10
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Myocardin MYOCD Tbio Non-IDG -2.37801 242.7 84
ETS domain-containing protein Elk-1 ELK1 Tbio Transcription Factor -0.51976 3.02 941
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Calcium/calmodulin-dependent protein kinase type II subunit delta CAMK2D Tchem Kinase -1.37613 16.9 229
Homeobox protein Nkx-2.5 NKX2-5 Tbio Transcription Factor -2.79738 600.1 385
Myocyte-specific enhancer factor 2D MEF2D Tbio Transcription Factor -1.96264 88.6 323
Myocyte-specific enhancer factor 2C MEF2C Tbio Transcription Factor -2.30705 184.5 974
Myocyte-specific enhancer factor 2A MEF2A Tbio Transcription Factor -2.53375 337.6 783
G1/S-specific cyclin-D2 CCND2 Tbio Non-IDG -2.66865 401.4 512