Development Level

Tbio 11 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

increased bone mineral density 2 | 72
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal limb bud morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 36
decreased caudal vertebrae num... 1 | 53
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
pallor 1 | 34
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 15 | 11,493
ovarian cancer 14 | 8,520
psoriasis 14 | 6,694
Cancer 13 | 2,499
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
osteosarcoma 11 | 7,950
Breast cancer 9 | 3,578
ependymoma 9 | 4,679
medulloblastoma, large-cell 9 | 6,241
oligodendroglioma 8 | 2,850
pancreatic cancer 7 | 2,398
Schizophrenia 6 | 1,160
astrocytic glioma 6 | 2,597
group 3 medulloblastoma 6 | 4,104
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung cancer 6 | 4,740
Pick disease 5 | 1,894
breast carcinoma 5 | 1,638
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
primary pancreatic ductal adenocarcinoma 5 | 1,109
Kidney cancer 4 | 2,613
Liver cancer 4 | 604
Melanoma 4 | 711
Osteoporosis 4 | 363
Parkinson's disease 4 | 392
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
gastric carcinoma 4 | 807
non primary Sjogren syndrome sicca 4 | 891
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Carcinoma, Hepatocellular 3 | 228
Colonic Neoplasms 3 | 142
Colorectal Neoplasms 3 | 243
Craniofacial Abnormalities 3 | 151
Duchenne muscular dystrophy 3 | 601
Endometrial cancer 3 | 311
Familial adenomatous polyposis 3 | 32
Immune system cancer 3 | 140
Increased hepatocellular carcinoma risk 3 | 27
Increased incidence of hepatocellular carcinoma 3 | 27
Intellectual disability 3 | 1,016
Large intestine cancer 3 | 126
Liver carcinoma 3 | 240
Liver neoplasms 3 | 130
Lymphoid leukemia 3 | 160
Micronodular cirrhosis 3 | 12
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Skin cancer 3 | 469
Somatic mutation 3 | 61
Subacute progressive viral hepatitis 3 | 9
Vascular disease 3 | 319
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Abnormality of retinal pigmentation 2 | 111
Acquired scoliosis 2 | 281
Adenoma 2 | 167
Alopecia 2 | 115
Bipolar Disorder 2 | 666
Chronic obstructive pulmonary disease 2 | 184
Curvature of spine 2 | 282
Hypoplasia of corpus callosum 2 | 90
Liver Cirrhosis, Experimental 2 | 769
Lung Neoplasms 2 | 232
Major Depressive Disorder 2 | 301
Malabsorption 2 | 82
Neoplasm Invasiveness 2 | 161
Neurodevelopmental Disorders 2 | 70
Osteoarthritis 2 | 184
Retinal pigment epithelial abnormality 2 | 111
Stomach Neoplasms 2 | 300
Strabismus 2 | 270
Systemic lupus erythematosus 2 | 194
astrocytoma 2 | 1,146
head and neck cancer 2 | 271
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192
Male tissues 15 | 17,142
Skin and soft tissues 15 | 17,230

Target Family

Non-IDG 8 | 12,091
GPCR 3 | 408
Enzyme 2 | 4,145
Kinase 2 | 634
Transcription Factor 2 | 1,400

WikiPathways Pathway

Regulation of Wnt/B-catenin Si... 17 | 17
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysophospholipid acyltransferase 1 MBOAT1 Tdark Enzyme -0.99280 9.62 23
Frizzled-7 FZD7 Tbio GPCR -1.81873 66.4 345
Frizzled-8 FZD8 Tbio GPCR -1.64874 42.5 233
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.76391 516.8 355
Adenomatous polyposis coli protein APC Tbio Non-IDG -1.90646 66.5 508
Frizzled-1 FZD1 Tbio GPCR -2.07049 78.4 286
Lymphoid enhancer-binding factor 1 LEF1 Tchem Transcription Factor -2.60971 375.2 591
Axin-1 AXIN1 Tbio Non-IDG -2.52218 301.0 370
Transcription factor 4 TCF4 Tbio Transcription Factor -2.57908 320.1 249
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -3.00390 610.8 955