Development Level

Tbio 11 | 11,445
Tchem 8 | 1,598
Tclin 3 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal head morphology 1 | 10
abnormal liver morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged spleen 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
increased hematocrit 1 | 46
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

Cancer 15 | 2,499
ovarian cancer 14 | 8,520
medulloblastoma, large-cell 12 | 6,241
osteosarcoma 12 | 7,950
psoriasis 12 | 6,694
Carcinoma 10 | 11,493
atypical teratoid / rhabdoid tumor 10 | 5,112
glioblastoma 10 | 5,792
ependymoma 9 | 4,679
lung cancer 9 | 4,740
invasive ductal carcinoma 8 | 2,951
Breast cancer 7 | 3,578
Vascular disease 7 | 319
adult high grade glioma 7 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
Alzheimer's disease 6 | 658
Astrocytoma, Pilocytic 6 | 3,081
Bipolar Disorder 6 | 666
Prostatic Neoplasms 6 | 495
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung carcinoma 6 | 2,843
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Breast Neoplasms 5 | 445
Mammary Neoplasms 5 | 425
Multiple myeloma 5 | 1,332
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
astrocytic glioma 5 | 2,597
cutaneous lupus erythematosus 5 | 1,057
group 4 medulloblastoma 5 | 1,855
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
Adenoma 4 | 167
Colonic Neoplasms 4 | 142
Depressive disorder 4 | 409
Kidney cancer 4 | 2,613
Liver Neoplasms, Experimental 4 | 59
Lung Neoplasms 4 | 232
Myocardial Infarction 4 | 151
Stomach Neoplasms 4 | 300
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer Disease 3 | 83
Asthma 3 | 385
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Non-Small-Cell Lung 3 | 107
Cardiomegaly 3 | 116
Cerebral Hemorrhage 3 | 42
Chronic lymphoid leukemia, disease 3 | 13
Diabetes Mellitus, Experimental 3 | 108
Esophageal Neoplasms 3 | 69
Fever 3 | 138
Liver carcinoma 3 | 240
Lymphoid leukemia 3 | 160
Nerve Degeneration 3 | 121
Osteoarthritis 3 | 184
Pain 3 | 103
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Polycystic ovary syndrome 3 | 360
Toxic encephalopathy 3 | 141
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
non-small cell lung carcinoma 3 | 317
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
ulcerative colitis 3 | 1,819
Abdomen distended 2 | 43
Arthrogryposis 2 | 54
Autistic Disorder 2 | 364
Bipolar disorder in remission 2 | 19
Colorectal Neoplasms 2 | 243
Death in early childhood 2 | 82
Death in infancy 2 | 82
Disease Models, Animal 2 | 155
Dystrophia unguium 2 | 53
Heart failure 2 | 162
Hydronephrosis 2 | 89
Isolated cases 2 | 72
Nail dysplasia 2 | 52
Osteochondrodysplasias 2 | 72
Osteoporosis 2 | 363
Polyhydramnios 2 | 108
Prenatal onset 2 | 139
RENAL ADYSPLASIA 2 | 25
Renal dysplasia 2 | 28
hearing impairment 2 | 199

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Respiratory system 21 | 16,393

Target Family

Non-IDG 17 | 12,091
Kinase 4 | 634
Transcription Factor 1 | 1,400

WikiPathways Pathway

Regulation of Apoptosis by Par... 22 | 22
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bcl-2-related ovarian killer protein BOK Tbio Non-IDG -1.64193 42.6 207
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
Integrin beta-4 ITGB4 Tbio Non-IDG -2.26591 177.4 704
Bcl-2-related protein A1 BCL2A1 Tchem Non-IDG -3.07855 1146.2 307
Bcl-2 homologous antagonist/killer BAK1 Tbio Non-IDG -2.29199 175.9 554
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.11278 12358.0 2705
Bcl-2-like protein 10 BCL2L10 Tchem Non-IDG -2.76119 562.2 165
Bcl-2-like protein 15 BCL2L15 Tbio Non-IDG -1.05536 11.5 94
Bcl-2-like protein 13 BCL2L13 Tbio Non-IDG -1.56317 34.2 204