Development Level

Tbio 34 | 11,445
Tchem 22 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 4 | 278
decreased circulating sodium l... 2 | 22
embryonic lethality prior to o... 2 | 239
increased circulating free fat... 2 | 20
increased erythrocyte cell num... 2 | 39
increased leukocyte cell numbe... 2 | 47
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal startle reflex 1 | 15
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased hematocrit 1 | 46
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9

Disease

Cancer 33 | 2,499
Carcinoma 33 | 11,493
ovarian cancer 33 | 8,520
psoriasis 33 | 6,694
glioblastoma 29 | 5,792
osteosarcoma 26 | 7,950
atypical teratoid / rhabdoid tumor 22 | 5,112
lung cancer 22 | 4,740
adult high grade glioma 21 | 3,801
medulloblastoma, large-cell 20 | 6,241
Astrocytoma, Pilocytic 18 | 3,081
ependymoma 17 | 4,679
Breast cancer 14 | 3,578
juvenile dermatomyositis 14 | 1,187
Multiple Sclerosis 13 | 540
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
malignant mesothelioma 13 | 3,232
Influenza 12 | 142
cystic fibrosis 12 | 1,696
group 4 medulloblastoma 12 | 1,855
Breast Neoplasms 11 | 445
Mammary Neoplasms 11 | 425
subependymal giant cell astrocytoma 11 | 2,287
Arthritis 10 | 290
group 3 medulloblastoma 10 | 4,104
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
oligodendroglioma 10 | 2,850
tuberculosis 10 | 2,010
Asthma 9 | 385
Melanoma 9 | 711
cutaneous lupus erythematosus 9 | 1,057
dermatomyositis 9 | 966
diabetes mellitus 9 | 1,728
lung carcinoma 9 | 2,843
pancreatic cancer 9 | 2,398
primitive neuroectodermal tumor 9 | 3,035
Lung disease 8 | 142
Rheumatoid arthritis 8 | 1,191
Schizophrenia 8 | 1,160
invasive ductal carcinoma 8 | 2,951
lung adenocarcinoma 8 | 2,716
non-small cell lung cancer 8 | 2,890
Hypersensitivity reaction type II disease 7 | 253
Inflammatory bowel disease 7 | 151
Kidney cancer 7 | 2,613
Liver Cirrhosis, Experimental 7 | 769
Systemic lupus erythematosus 7 | 194
breast carcinoma 7 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primary Sjogren syndrome 7 | 735
ulcerative colitis 7 | 1,819
Autosomal recessive predisposition 6 | 1,442
Brain Ischemia 6 | 110
Carcinoma, Hepatocellular 6 | 228
Hepatitis C 6 | 94
Liver carcinoma 6 | 240
Microphthalmia with limb anomalies 6 | 40
Multiple myeloma 6 | 1,332
Pick disease 6 | 1,894
Pneumonia 6 | 174
Reperfusion Injury 6 | 86
Vascular disease 6 | 319
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Atherosclerosis 5 | 291
Cholestasis 5 | 155
Cholestasis, Extrahepatic 5 | 25
Colonic Neoplasms 5 | 142
Coronary artery disease 5 | 268
Crohn's disease 5 | 321
Dermatitis 5 | 157
Encephalitis 5 | 64
Gaucher disease type 1 5 | 180
Hepatitis 5 | 67
Immunologic Deficiency Syndromes 5 | 113
Influenza, Human 5 | 51
Kidney disease 5 | 430
Lung Neoplasms 5 | 232
Major Depressive Disorder 5 | 301
Stomach Neoplasms 5 | 300
Unipolar Depression 5 | 250
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
astrocytic glioma 5 | 2,597
colon cancer 5 | 1,478
hepatocellular carcinoma 5 | 547
non primary Sjogren syndrome sicca 5 | 891
periodontitis 5 | 293
sarcoidosis 5 | 370
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Depressive disorder 4 | 409
Mental Depression 4 | 333
Myocardial Ischemia 4 | 169
Waldenstrons macroglobulinemia 4 | 765
astrocytoma 4 | 1,146
pituitary cancer 4 | 1,972

Tissue

Blood and immune system 58 | 16,909
Digestive Tract 57 | 17,369
Endocrine System 57 | 18,159
Female tissues 57 | 17,400
Male tissues 57 | 17,142
Nervous System 57 | 16,725
Skin and soft tissues 57 | 17,230
Urinary Tract 57 | 16,678
Liver and Pancreas 56 | 16,750
Respiratory system 56 | 16,393
Cardiovascular System 55 | 15,192

Target Family

Non-IDG 26 | 12,091
Kinase 15 | 634
Enzyme 14 | 4,145
Transcription Factor 4 | 1,400

WikiPathways Pathway

RIG-I-like Receptor Signaling 59 | 59
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of IKBKE 1 SIKE1 Tdark Non-IDG -0.71713 4.66 97
Triokinase/FMN cyclase TKFC Tbio Enzyme -2.07992 116.2 109
ATP-dependent RNA helicase DDX3Y DDX3Y Tbio Enzyme -1.81279 65.1 167
Stromal cell-derived factor 1 CXCL12 Tbio Non-IDG -3.48446 3085.9 607
Probable ATP-dependent RNA helicase DHX58 DHX58 Tbio Enzyme -1.62683 45.9 286
ATP-dependent RNA helicase DDX3X DDX3X Tchem Enzyme -2.32036 221.7 479
TANK-binding kinase 1-binding protein 1 TBKBP1 Tbio Enzyme -0.59007 2.79 127
TRAF family member-associated NF-kappa-B activator TANK Tbio Non-IDG -1.81992 67.5 373
E3 ubiquitin-protein ligase RNF125 RNF125 Tbio Enzyme -0.82828 7.89 139
5-azacytidine-induced protein 2 AZI2 Tdark Non-IDG -0.49902 3.55 69