Development Level

Tbio 118 | 11,445
Tchem 5 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
enlarged heart 2 | 210
increased circulating alkaline... 2 | 122
increased lymphocyte cell numb... 2 | 32
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spine curvature 1 | 9
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
limb grasping 1 | 41
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499

Disease

Cancer 84 | 2,499
psoriasis 75 | 6,694
Ankylosing spondylitis 71 | 140
Behcet's disease 70 | 89
diabetes mellitus 66 | 1,728
Carcinoma 58 | 11,493
Acquired immunodeficiency syndrome 57 | 197
Arthritis 57 | 290
Hypersensitivity reaction type II disease 57 | 253
Uveitis 57 | 103
Herpes zoster 56 | 68
Juvenile rheumatoid arthritis 56 | 111
Stevens-Johnson syndrome 53 | 92
Human immunodeficiency virus infectious disease 50 | 138
dermatomyositis 50 | 966
Psoriatic arthritis 49 | 86
ovarian cancer 49 | 8,520
Rheumatoid arthritis 40 | 1,191
Dermatitis 36 | 157
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
Multiple myeloma 33 | 1,332
lung cancer 31 | 4,740
glioblastoma 27 | 5,792
Anemia 25 | 365
tuberculosis 25 | 2,010
Hemochromatosis 23 | 54
Multiple Sclerosis 23 | 540
Skin disease 23 | 66
osteosarcoma 23 | 7,950
Hepatitis B 22 | 108
Kidney disease 22 | 430
Leprosy 22 | 73
Liver disease 22 | 237
Primary immunodeficiency disease 22 | 54
Birdshot chorioretinopathy 21 | 23
HIV Infections 17 | 102
Human immunodeficiency virus type 1, susceptibility to 15 | 26
Pre-Eclampsia 15 | 68
Psoriasis susceptibility 1 14 | 14
Breast cancer 13 | 3,578
atypical teratoid / rhabdoid tumor 12 | 5,112
ependymoma 12 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Astrocytoma, Pilocytic 11 | 3,081
adult high grade glioma 11 | 3,801
astrocytoma 11 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
malignant mesothelioma 11 | 3,232
medulloblastoma, large-cell 11 | 6,241
juvenile dermatomyositis 10 | 1,187
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
subependymal giant cell astrocytoma 10 | 2,287
Waldenstrons macroglobulinemia 9 | 765
astrocytic glioma 9 | 2,597
lung carcinoma 9 | 2,843
cutaneous lupus erythematosus 8 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
invasive ductal carcinoma 8 | 2,951
oligodendroglioma 8 | 2,850
group 3 medulloblastoma 7 | 4,104
Schizophrenia 6 | 1,160
breast carcinoma 6 | 1,638
pancreatic cancer 6 | 2,398
primary Sjogren syndrome 6 | 735
Liver Cirrhosis, Experimental 5 | 769
Mantle cell lymphoma 5 | 23
Pick disease 5 | 1,894
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
esophageal adenocarcinoma 5 | 737
non primary Sjogren syndrome sicca 5 | 891
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Duchenne muscular dystrophy 4 | 601
interstitial cystitis 4 | 2,312
pituitary cancer 4 | 1,972
Chemical and Drug Induced Liver Injury 3 | 195
Congestive heart failure 3 | 113
Diarrhea 3 | 253
Endometriosis 3 | 540
Glioma 3 | 74
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
hepatocellular carcinoma 3 | 547
inflammatory breast cancer 3 | 286
limb girdle muscular dystrophy 2I 3 | 32
posterior fossa group A ependymoma 3 | 468
primitive neuroectodermal tumor 3 | 3,035
tuberculosis and treatment for 3 months 3 | 179

Tissue

Digestive Tract 61 | 17,369
Endocrine System 61 | 18,159
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Respiratory system 61 | 16,393
Blood and immune system 60 | 16,909
Cardiovascular System 60 | 15,192
Male tissues 60 | 17,142
Nervous System 60 | 16,725
Skin and soft tissues 60 | 17,230
Urinary Tract 60 | 16,678

Target Family

Non-IDG 88 | 12,091
Enzyme 41 | 4,145

WikiPathways Pathway

Proteasome Degradation 129 | 129
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
HLA class I histocompatibility antigen, Cw-17 alpha chain HLA-C Tbio Non-IDG -1.90661 830.5 0
Histone H2A type 1-B/E HIST1H2AB Tbio Non-IDG -1.27041 18.5 133
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
HLA class I histocompatibility antigen, Cw-15 alpha chain HLA-C Tbio Non-IDG -1.90661 830.5 0