Development Level

Tbio 23 | 11,445
Tclin 7 | 613
Tchem 5 | 1,598
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

abnormal testis morphology 2 | 43
decreased vertical activity 2 | 208
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal heart morphology 1 | 162
abnormal ovary morphology 1 | 7
abnormal seminal vesicle morph... 1 | 114
absent epididymis 1 | 3
absent ovary 1 | 3
absent seminal vesicle 1 | 4
absent testes 1 | 6
cleft palate 1 | 8
cyanosis 1 | 7
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased lean body mass 1 | 135
decreased respiratory quotient 1 | 16
enlarged heart 1 | 210
female infertility 1 | 60
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating iron lev... 1 | 30
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
small testis 1 | 58
small uterus 1 | 3

Disease

Carcinoma 28 | 11,493
Prader-Willi syndrome 18 | 48
medulloblastoma, large-cell 18 | 6,241
ovarian cancer 16 | 8,520
Angelman syndrome 15 | 34
Schizophrenia 14 | 1,160
psoriasis 14 | 6,694
ependymoma 13 | 4,679
glioblastoma 13 | 5,792
malignant mesothelioma 13 | 3,232
Kidney cancer 12 | 2,613
adult high grade glioma 12 | 3,801
atypical teratoid / rhabdoid tumor 11 | 5,112
lung cancer 11 | 4,740
osteosarcoma 11 | 7,950
Autistic Disorder 10 | 364
Obesity 10 | 678
oligodendroglioma 10 | 2,850
Astrocytoma, Pilocytic 9 | 3,081
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Intellectual disability 9 | 1,016
Mental and motor retardation 9 | 608
astrocytic glioma 9 | 2,597
primitive neuroectodermal tumor 9 | 3,035
Alcoholic Intoxication, Chronic 8 | 289
Bipolar Disorder 8 | 666
Breast cancer 8 | 3,578
Epilepsy 8 | 792
group 3 medulloblastoma 8 | 4,104
lung carcinoma 8 | 2,843
Attention deficit hyperactivity disorder 7 | 278
Delayed speech and language development 7 | 112
Hypoplastic feet 7 | 66
Isolated cases 7 | 72
Language Delay 7 | 112
Speech Delay 7 | 112
Speech impairment 7 | 112
Tonic-clonic epilepsy 7 | 47
group 4 medulloblastoma 7 | 1,855
subependymal giant cell astrocytoma 7 | 2,287
Acquired scoliosis 6 | 281
Anxiety 6 | 136
Autosomal recessive predisposition 6 | 1,442
Congenital hypoplasia of penis 6 | 176
Curvature of spine 6 | 282
Dilated ventricles (finding) 6 | 121
Dull intelligence 6 | 645
General anesthesia 6 | 53
Hyperphagia 6 | 23
Hypogonadism, Isolated Hypogonadotropic 6 | 71
Hypogonadotropic hypogonadism 6 | 89
Increased appetite (finding) 6 | 23
Insomnia 6 | 20
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Motor delay 6 | 147
No development of motor milestones 6 | 147
Photosensitivity of skin 6 | 51
Pick disease 6 | 1,894
Poor school performance 6 | 645
Sedation as Adjunct to Anesthesia 6 | 15
Short stature 6 | 531
Specific learning disability 6 | 47
Strabismus 6 | 270
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
Alcohol withdrawal syndrome 5 | 20
Cancer 5 | 2,499
Curvature of digit 5 | 57
Decreased pain sensation 5 | 17
Delayed Puberty 5 | 97
Failure to thrive in infancy 5 | 32
Hyperactive behavior 5 | 91
Hyperinsulinism 5 | 133
Hyperkyphosis 5 | 111
Hyperopia 5 | 70
Hypoventilation 5 | 8
Infertility 5 | 188
Kyphosis deformity of spine 5 | 114
Long narrow head 5 | 75
Multiple myeloma 5 | 1,332
Narrow cranium shape 5 | 75
Narrow forehead 5 | 34
Narrow head shape 5 | 75
Narrow skull shape 5 | 75
Obesity, Abdominal 5 | 24
Recurrent respiratory infections 5 | 141
Reduced fetal movement 5 | 51
Respiratory Depression 5 | 10
Schizoaffective Disorder 5 | 55
Short hands 5 | 50
Small hand 5 | 36
Status Epilepticus 5 | 98
Tetanus 5 | 68
Thin upper lip vermilion 5 | 67
Turridolichocephaly 5 | 75
ductal carcinoma in situ 5 | 1,745

Tissue

Endocrine System 36 | 18,159
Female tissues 35 | 17,400
Skin and soft tissues 35 | 17,230
Male tissues 34 | 17,142
Nervous System 34 | 16,725
Digestive Tract 33 | 17,369
Blood and immune system 32 | 16,909
Urinary Tract 32 | 16,678
Respiratory system 31 | 16,393
Liver and Pancreas 30 | 16,750
Cardiovascular System 26 | 15,192

Target Family

Non-IDG 16 | 12,091
Ion Channel 9 | 344
Enzyme 4 | 4,145
Transcription Factor 4 | 1,400
Transporter 2 | 473
GPCR 1 | 408
Kinase 1 | 634

WikiPathways Pathway

Prader-Willi and Angelman Synd... 37 | 37
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
SNRPN upstream reading frame protein SNURF Tbio Non-IDG -1.05125 8.44 12
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Fasciculation and elongation protein zeta-2 FEZ2 Tbio Non-IDG -0.40742 2.26 141
Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 Tbio Ion Channel -1.74365 53.9 92
Gamma-aminobutyric acid receptor subunit beta-3 GABRB3 Tclin Ion Channel -2.13205 136.0 202
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
Nuclear pore-associated protein 1 NPAP1 Tdark Non-IDG -0.73373 4.82 34
Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 Tclin Ion Channel -0.98683 8.48 87