Development Level

Tchem 17 | 1,598
Tbio 5 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal sleep behavior 1 | 70
decreased body weight 1 | 161
decreased circulating triglyce... 1 | 79
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
hyperactivity 1 | 148
increased IgA level 1 | 1
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased kidney weight 1 | 6
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
thrombocytopenia 1 | 56

Disease

Cancer 18 | 2,499
lung cancer 17 | 4,740
Carcinoma 16 | 11,493
osteosarcoma 14 | 7,950
ovarian cancer 14 | 8,520
psoriasis 14 | 6,694
glioblastoma 12 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Schizophrenia 10 | 1,160
medulloblastoma, large-cell 10 | 6,241
atypical teratoid / rhabdoid tumor 9 | 5,112
Breast cancer 8 | 3,578
Lung Neoplasms 8 | 232
Toxic encephalopathy 8 | 141
non-small cell lung cancer 8 | 2,890
Astrocytoma, Pilocytic 7 | 3,081
Breast Neoplasms 7 | 445
Cholestasis 7 | 155
Mammary Neoplasms 7 | 425
Parkinson's disease 7 | 392
Prostatic Neoplasms 7 | 495
Rheumatoid arthritis 7 | 1,191
Vascular disease 7 | 319
diabetes mellitus 7 | 1,728
lung carcinoma 7 | 2,843
malignant mesothelioma 7 | 3,232
non-small cell lung carcinoma 7 | 317
Alzheimer's disease 6 | 658
Chemical and Drug Induced Liver Injury 6 | 195
Colorectal Neoplasms 6 | 243
Kidney disease 6 | 430
Liver disease 6 | 237
Obesity 6 | 678
adult high grade glioma 6 | 3,801
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
tuberculosis 6 | 2,010
Adverse reaction to drug 5 | 61
Arthritis 5 | 290
Asthma 5 | 385
Autosomal recessive predisposition 5 | 1,442
Carcinoma, Hepatocellular 5 | 228
Carcinoma, Non-Small-Cell Lung 5 | 107
Contact Dermatitis 5 | 81
Dermatitis, Contact 5 | 71
Drug-Related Side Effects and Adverse Reactions 5 | 62
Hyperglycemia 5 | 137
Hypertension 5 | 396
Liver Cirrhosis, Experimental 5 | 769
Liver cancer 5 | 604
Liver carcinoma 5 | 240
adrenocortical carcinoma 5 | 1,428
aldosterone-producing adenoma 5 | 665
ependymoma 5 | 4,679
gastric cancer 5 | 459
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
Acute kidney injury 4 | 70
Arthritis, Rheumatoid 4 | 174
Bilirubin metabolic disorder 4 | 41
Brain disease 4 | 96
Down syndrome 4 | 499
Eye disease 4 | 62
Hypertensive disease 4 | 292
Liver neoplasms 4 | 130
Lung disease 4 | 142
Myocardial Ischemia 4 | 169
Reperfusion Injury 4 | 86
Status Epilepticus 4 | 98
Stomach Neoplasms 4 | 300
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
cystic fibrosis 4 | 1,696
hepatocellular carcinoma 4 | 547
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
nephrosclerosis 4 | 333
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
posterior fossa group A ependymoma 4 | 468
subependymal giant cell astrocytoma 4 | 2,287
Amphetamine-Related Disorders 3 | 74
Chronic obstructive pulmonary disease 3 | 184
Disease Progression 3 | 136
Endometriosis 3 | 540
Epilepsy 3 | 792
Heart disease 3 | 306
Hepatomegaly 3 | 285
Kidney cancer 3 | 2,613
Waldenstrons macroglobulinemia 3 | 765
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
fibroadenoma 3 | 559
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
ulcerative colitis 3 | 1,819
urothelial carcinoma 3 | 318

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Cardiovascular System 22 | 15,192

Target Family

Enzyme 8 | 4,145
Kinase 5 | 634
Transporter 5 | 473
Transcription Factor 3 | 1,400
Non-IDG 2 | 12,091

WikiPathways Pathway

Photodynamic therapy-induced N... 23 | 23
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sulfiredoxin-1 SRXN1 Tbio Non-IDG -1.21582 18.8 67
NAD(P)H dehydrogenase [quinone] 1 NQO1 Tchem Enzyme -3.12097 1326.4 550
Canalicular multispecific organic anion transporter 2 ABCC3 Tbio Transporter -2.46032 287.4 214
Multidrug resistance-associated protein 4 ABCC4 Tchem Transporter -2.56001 341.6 352
Kelch-like ECH-associated protein 1 KEAP1 Tclin Non-IDG -2.99364 962.4 463
Multidrug resistance-associated protein 6 ABCC6 Tbio Transporter -2.71911 547.1 100
Canalicular multispecific organic anion transporter 1 ABCC2 Tchem Transporter -2.90204 834.9 234
Nuclear factor erythroid 2-related factor 2 NFE2L2 Tchem Transcription Factor -3.14284 1506.7 552
Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 Tchem Enzyme -1.92807 86.0 320
Proto-oncogene c-Fos FOS Tbio Transcription Factor -4.14231 13598.8 1058