Development Level

Tchem 20 | 1,388
Tbio 15 | 11,651
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased circulating HDL chol... 2 | 68
abnormal coat-hair pigmentatio... 1 | 64
abnormal lung morphology 1 | 26
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased eosinophil cell numb... 1 | 24
decreased lactate dehydrogenas... 1 | 16
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
short tibia 1 | 97

Disease

Cancer 32 | 2,499
ovarian cancer 29 | 8,520
psoriasis 25 | 6,694
glioblastoma 24 | 5,792
osteosarcoma 23 | 7,950
pancreatic cancer 22 | 2,398
lung cancer 21 | 4,740
Carcinoma 20 | 11,493
medulloblastoma, large-cell 19 | 6,241
diabetes mellitus 18 | 1,728
ependymoma 18 | 4,679
non-small cell lung cancer 17 | 2,890
atypical teratoid / rhabdoid tumor 16 | 5,112
ulcerative colitis 16 | 1,819
invasive ductal carcinoma 15 | 2,951
group 3 medulloblastoma 14 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
malignant mesothelioma 14 | 3,232
Breast cancer 13 | 3,578
lung adenocarcinoma 13 | 2,716
adrenocortical carcinoma 12 | 1,428
breast carcinoma 12 | 1,638
ductal carcinoma in situ 12 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
Vascular disease 11 | 319
adult high grade glioma 11 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
Colonic Neoplasms 10 | 142
Hypertension 10 | 396
Prostatic Neoplasms 10 | 495
Stomach Neoplasms 10 | 300
dermatomyositis 10 | 966
interstitial cystitis 10 | 2,312
oligodendroglioma 10 | 2,850
tuberculosis 10 | 2,010
Bipolar Disorder 9 | 666
Carcinoma, Hepatocellular 9 | 228
Diabetes Mellitus, Experimental 9 | 108
Liver carcinoma 9 | 240
Obesity 9 | 678
cystic fibrosis 9 | 1,696
lung carcinoma 9 | 2,843
primitive neuroectodermal tumor 9 | 3,035
Astrocytoma, Pilocytic 8 | 3,081
Breast Neoplasms 8 | 445
Hypertensive disease 8 | 292
Kidney disease 8 | 430
Liver Cirrhosis, Experimental 8 | 769
Mammary Neoplasms 8 | 425
astrocytic glioma 8 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
primary pancreatic ductal adenocarcinoma 8 | 1,109
Acute kidney injury 7 | 70
Coronary artery disease 7 | 268
Endometriosis 7 | 540
Hyperglycemia 7 | 137
Inflammation 7 | 120
Myocardial Infarction 7 | 151
Polycystic ovary syndrome 7 | 360
Rheumatoid arthritis 7 | 1,191
acute quadriplegic myopathy 7 | 1,158
cutaneous lupus erythematosus 7 | 1,057
nasopharyngeal carcinoma 7 | 1,058
Autosomal recessive predisposition 6 | 1,442
Cerebrovascular disease 6 | 238
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
Diabetic retinopathy 6 | 56
Heart failure 6 | 162
Hyperinsulinism 6 | 133
Hypoglycemia 6 | 152
Lung disease 6 | 142
Major Depressive Disorder 6 | 301
Mood Disorders 6 | 184
Seizures 6 | 596
astrocytoma 6 | 1,146
esophageal adenocarcinoma 6 | 737
pediatric high grade glioma 6 | 1,064
Asthma 5 | 385
Atherosclerosis 5 | 291
Carcinoma, Renal Cell 5 | 124
Cell Transformation, Neoplastic 5 | 97
Colorectal Neoplasms 5 | 243
Diabetes Mellitus, Type 2 5 | 142
Esophageal Neoplasms 5 | 69
Heart disease 5 | 306
Liver Cirrhosis 5 | 181
Liver disease 5 | 237
Lung Neoplasms 5 | 232
Melanoma 5 | 711
Mental Depression 5 | 333
Multiple myeloma 5 | 1,332
Myocardial Ischemia 5 | 169
Neoplastic Cell Transformation 5 | 89
Neurodegenerative disease 5 | 414
Renal Cell Carcinoma 5 | 214
Schizophrenia 5 | 1,160
Unipolar Depression 5 | 250
colon cancer 5 | 1,478
gastric carcinoma 5 | 807
pituitary cancer 5 | 1,972

Tissue

Blood and immune system 37 | 16,909
Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678
Cardiovascular System 36 | 15,192
Nervous System 36 | 16,725

Target Family

Non-IDG 23 | 12,091
Enzyme 4 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400
Transporter 3 | 473

WikiPathways Pathway

Photodynamic therapy-induced H... 37 | 37
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
ATP-dependent 6-phosphofructokinase, liver type PFKL Tbio Kinase -2.07015 107.6 240
Hypoxia-inducible factor 1-alpha inhibitor HIF1AN Tbio Non-IDG -1.91636 75.1 429
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981
Protransforming growth factor alpha TGFA Tbio Non-IDG -2.15761 135.3 697
Aryl hydrocarbon receptor nuclear translocator ARNT Tbio Transcription Factor -2.53687 261.2 474
Erythropoietin EPO Tbio Non-IDG -3.92285 8985.5 837
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.35760 2176.5 510
Vascular endothelial growth factor A VEGFA Tclin Non-IDG -4.27197 19076.6 1809
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298