Development Level

Tchem 36 | 1,598
Tclin 32 | 613
Tbio 7 | 11,445

Collection

GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

decreased vertical activity 2 | 208
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased mean corpuscular hem... 2 | 36
abnormal coat-hair pigmentatio... 1 | 64
abnormal colon morphology 1 | 3
abnormal heart morphology 1 | 162
abnormal ileum morphology 1 | 2
abnormal kidney morphology 1 | 65
abnormal male genitalia morpho... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
absent startle reflex 1 | 24
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
fusion of vertebral arches 1 | 7
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating total pr... 1 | 28
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
polycystic kidney 1 | 15
polysyndactyly 1 | 2
preweaning lethality, complete... 1 | 979
prolonged RR interval 1 | 8
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16
vertebral transformation 1 | 12

Disease

Carcinoma 60 | 11,493
psoriasis 39 | 6,694
osteosarcoma 28 | 7,950
Cancer 26 | 2,499
ovarian cancer 25 | 8,520
medulloblastoma, large-cell 24 | 6,241
glioblastoma 22 | 5,792
lung cancer 20 | 4,740
Astrocytoma, Pilocytic 19 | 3,081
invasive ductal carcinoma 18 | 2,951
adult high grade glioma 17 | 3,801
interstitial cystitis 17 | 2,312
lung carcinoma 17 | 2,843
ulcerative colitis 17 | 1,819
atypical teratoid / rhabdoid tumor 16 | 5,112
cutaneous lupus erythematosus 15 | 1,057
ependymoma 15 | 4,679
Alcoholic Intoxication, Chronic 14 | 289
Obesity 14 | 678
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
lung adenocarcinoma 14 | 2,716
non-small cell lung cancer 14 | 2,890
oligodendroglioma 13 | 2,850
Depressive disorder 12 | 409
Schizophrenia 12 | 1,160
ductal carcinoma in situ 12 | 1,745
tuberculosis 12 | 2,010
Asthma 11 | 385
Rheumatoid arthritis 11 | 1,191
Status Epilepticus 11 | 98
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
malignant mesothelioma 11 | 3,232
Breast cancer 10 | 3,578
Multiple Sclerosis 10 | 540
astrocytic glioma 10 | 2,597
colon cancer 10 | 1,478
pancreatic cancer 10 | 2,398
primitive neuroectodermal tumor 10 | 3,035
Autosomal recessive predisposition 9 | 1,442
adrenocortical carcinoma 9 | 1,428
subependymal giant cell astrocytoma 9 | 2,287
Alcoholism 8 | 45
Bipolar Disorder 8 | 666
Hypertension 8 | 396
Kidney cancer 8 | 2,613
Mental Depression 8 | 333
Pain agnosia 8 | 104
breast carcinoma 8 | 1,638
primary Sjogren syndrome 8 | 735
Adenoma 7 | 167
Epilepsy 7 | 792
Human immunodeficiency virus infectious disease 7 | 138
Kidney disease 7 | 430
Mood Disorders 7 | 184
Pain 7 | 103
Substance Withdrawal Syndrome 7 | 55
diabetes mellitus 7 | 1,728
hepatocellular carcinoma 7 | 547
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pituitary cancer 7 | 1,972
Arthritis 6 | 290
Cocaine-Related Disorders 6 | 92
Constipation 6 | 181
Hyperalgesia 6 | 83
Hypersensitivity 6 | 63
Hypertensive disease 6 | 292
Opiate dependence 6 | 29
Pneumonia 6 | 174
cystic fibrosis 6 | 1,696
mucosa-associated lymphoid tissue lymphoma 6 | 484
Acquired immunodeficiency syndrome 5 | 197
Acromegaly 5 | 51
Alcohol abuse 5 | 50
Atherosclerosis 5 | 291
Carcinoid syndrome 5 | 5
Cocaine Dependence 5 | 51
Diarrhea from Pancreatic VIPoma 5 | 5
Hypersensitivity reaction type II disease 5 | 253
Inflammatory bowel disease 5 | 151
Major Depressive Disorder 5 | 301
Pick disease 5 | 1,894
Pituitary adenoma 5 | 38
Seizures 5 | 596
Unipolar Depression 5 | 250
astrocytoma 5 | 1,146
gastric carcinoma 5 | 807
group 4 medulloblastoma 5 | 1,855
head and neck cancer 5 | 271
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
pancreatic carcinoma 5 | 562
primary pancreatic ductal adenocarcinoma 5 | 1,109
Cushing's syndrome 4 | 48
Delayed bone age 4 | 136
Down syndrome 4 | 499
Heart disease 4 | 306
Hypercortisolism 4 | 8
Psychotic Disorders 4 | 151
Skin cancer 4 | 469
nephrosclerosis 4 | 333

Tissue

Endocrine System 73 | 18,159
Nervous System 66 | 16,725
Digestive Tract 63 | 17,369
Female tissues 63 | 17,400
Skin and soft tissues 62 | 17,230
Male tissues 61 | 17,142
Blood and immune system 58 | 16,909
Liver and Pancreas 57 | 16,750
Urinary Tract 57 | 16,678
Respiratory system 55 | 16,393
Cardiovascular System 48 | 15,192

Target Family

GPCR 73 | 408
Non-IDG 1 | 12,091
Transporter 1 | 473

WikiPathways Pathway

Peptide GPCRs 75 | 75
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adrenocorticotropic hormone receptor MC2R Tclin GPCR -2.22640 172.4 223
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.14265 126.2 303
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Somatostatin receptor type 2 SSTR2 Tclin GPCR -2.53936 363.5 246
Tachykinin-4 TAC4 Tbio Non-IDG -1.56554 37.9 57
Phospholipid-transporting ATPase IA ATP8A1 Tbio Transporter -1.56158 35.5 43
C-X-C chemokine receptor type 2 CXCR2 Tchem GPCR -2.87313 723.9 643
Melanocortin receptor 3 MC3R Tchem GPCR -2.65556 445.3 202
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.48051 278.1 378
N-formyl peptide receptor 3 FPR3 Tchem GPCR -1.41613 24.4 247