Development Level

Tbio 26 | 10,625
Tclin 14 | 602
Tchem 12 | 1,890
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
abnormal retina morphology 2 | 100
decreased circulating fructosa... 2 | 31
hydrops fetalis 2 | 22
increased leukocyte cell numbe... 2 | 37
preweaning lethality, incomple... 2 | 260
abnormal bone mineralization 1 | 55
abnormal coat/hair pigmentatio... 1 | 54
abnormal hair texture 1 | 4
abnormal head morphology 1 | 10
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
decreased NK T cell number 1 | 28
decreased body weight 1 | 174
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased hematocrit 1 | 25
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
fusion of vertebral arches 1 | 7
increased bone mineral density 1 | 52
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
vertebral fusion 1 | 23

Disease

ovarian cancer 36 | 8,484
osteosarcoma 26 | 7,933
Cancer 23 | 2,346
psoriasis 23 | 6,685
glioblastoma 20 | 5,572
lung cancer 20 | 4,466
medulloblastoma, large-cell 20 | 6,234
pancreatic cancer 20 | 2,300
atypical teratoid / rhabdoid tumor 17 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
non-small cell lung cancer 16 | 2,798
Breast cancer 15 | 3,094
pilocytic astrocytoma 15 | 3,086
primary pancreatic ductal adenocarcinoma 14 | 1,271
Duchenne muscular dystrophy 12 | 602
juvenile dermatomyositis 12 | 1,189
Multiple myeloma 11 | 1,327
Ocular hypertension 11 | 27
diabetes mellitus 11 | 1,663
interstitial cystitis 11 | 2,299
invasive ductal carcinoma 11 | 2,950
lung adenocarcinoma 11 | 2,713
lung carcinoma 11 | 2,844
malignant mesothelioma 11 | 3,162
primitive neuroectodermal tumor 11 | 3,031
Nephroblastoma 10 | 45
breast carcinoma 10 | 1,614
subependymal giant cell astrocytoma 10 | 2,287
tuberculosis 10 | 1,557
ulcerative colitis 10 | 2,087
Acute lymphoid leukemia 9 | 25
Anaplastic large T-cell systemic malignant lymphoma 9 | 10
Burkitt's lymphoma 9 | 15
Carcinoma of breast 9 | 11
Carcinoma of female breast 9 | 20
Diffuse non-Hodgkin's lymphoma, large cell 9 | 12
Follicular non-Hodgkin's lymphoma 9 | 17
Gestational trophoblastic neoplasia 9 | 14
HER2-positive carcinoma of breast 9 | 10
Hodgkin's disease 9 | 18
Hypertensive disorder 9 | 58
Kaposi's sarcoma 9 | 20
Langerhans cell histiocytosis, disseminated 9 | 10
Liposarcoma 9 | 20
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Malignant tumor of prostate 9 | 11
Malignant tumor of stomach 9 | 12
Malignant tumor of testis 9 | 11
Metastatic Breast Carcinoma 9 | 21
Metastatic Prostate Carcinoma 9 | 18
Mycosis fungoides 9 | 28
Neuroblastoma 9 | 78
Non-Hodgkin's lymphoma 9 | 22
Open-angle glaucoma 9 | 26
Rhabdomyosarcoma 9 | 29
Rheumatoid Arthritis 9 | 1,160
Secondary malignant neoplasm of pancreas 9 | 10
Transitional cell carcinoma 9 | 18
astrocytic glioma 9 | 2,241
astrocytoma 9 | 1,493
colon cancer 9 | 1,475
cystic fibrosis 9 | 1,665
group 4 medulloblastoma 9 | 1,875
oligodendroglioma 9 | 2,849
adult high grade glioma 8 | 2,148
pediatric high grade glioma 8 | 2,712
Animal Mammary Neoplasms 7 | 136
Carcinoma 7 | 2,147
Down syndrome 7 | 548
Mammary Neoplasms 7 | 410
Mammary Neoplasms, Experimental 7 | 150
Waldenstrons macroglobulinemia 7 | 765
adrenocortical carcinoma 7 | 1,427
dermatomyositis 7 | 933
ependymoma 7 | 2,514
gastric cancer 7 | 430
gastric carcinoma 7 | 832
medulloblastoma 7 | 1,524
mucosa-associated lymphoid tissue lymphoma 7 | 480
pancreatic carcinoma 7 | 567
Becker muscular dystrophy 6 | 187
Condyloma acuminatum 6 | 7
Lissencephaly 6 | 61
Neoplasm Invasiveness 6 | 127
acute quadriplegic myopathy 6 | 1,157
ductal carcinoma in situ 6 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
pituitary cancer 6 | 1,972
posterior fossa group B ependymoma 6 | 1,530
sonic hedgehog group medulloblastoma 6 | 1,482
Intellectual disability 5 | 573
Pick disease 5 | 1,893
Prostatic Neoplasms 5 | 471
cutaneous lupus erythematosus 5 | 1,056
esophageal adenocarcinoma 5 | 737
hepatocellular carcinoma 5 | 532
primary Sjogren syndrome 5 | 789

Tissue

Blood and immune system 54 | 17,995
Cardiovascular System 54 | 17,958
Digestive Tract 54 | 18,473
Endocrine System 54 | 18,512
Female tissues 54 | 18,647
Liver and Pancreas 54 | 18,136
Male tissues 54 | 17,969
Nervous System 54 | 18,561
Respiratory system 54 | 17,484
Urinary Tract 54 | 18,444
Skin and soft tissues 53 | 18,115

Target Family

Non-IDG 47 | 11,971
Kinase 5 | 634
Enzyme 2 | 4,146

WikiPathways Pathway

Pathogenic Escherichia coli in... 54 | 54
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin beta-2A chain TUBB2A Tclin Non-IDG -1.58651 36.1 215
Transforming protein RhoA RHOA Tbio Enzyme -3.48838 3096.5 467
Tyrosine-protein kinase ABL1 ABL1 Tclin Kinase -3.47805 3222.2 1533
Actin-related protein 2/3 complex subunit 5 ARPC5 Tbio Non-IDG -1.07398 11.5 63
Rho-associated protein kinase 2 ROCK2 Tclin Kinase -2.39656 248.3 472
Tubulin alpha-1A chain TUBA1A Tchem Non-IDG -1.55267 35.2 218
Lymphocyte antigen 96 LY96 Tbio Non-IDG -2.69962 490.7 314
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.83965 6.79 66
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.35945 217.4 316
Tubulin beta-8 chain TUBB8 Tclin Non-IDG -0.30103 3.00 61