Development Level

Tbio 19 | 10,625
Tchem 16 | 1,890
Tclin 3 | 602
Tdark 1 | 7,003

IMPC Term

abnormal behavior 3 | 226
short tibia 3 | 82
cardiovascular system phenotyp... 2 | 35
male infertility 2 | 62
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pelvic girdle bone mo... 1 | 11
abnormal spinal cord morpholog... 1 | 8
abnormal spine curvature 1 | 7
abnormal tooth morphology 1 | 24
absent teeth 1 | 4
decreased Ly6C-positive mature... 1 | 4
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased effector memory CD8-... 1 | 24
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased rib number 1 | 59
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased CD11b-high dendritic... 1 | 5
increased NK cell number 1 | 19
increased circulating alkaline... 1 | 119
increased circulating sodium l... 1 | 71
increased dendritic cell numbe... 1 | 2
increased heart weight 1 | 37
increased or absent threshold ... 1 | 128
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
small liver 1 | 8
small spleen 1 | 11
thrombocytopenia 1 | 46

Disease

ovarian cancer 25 | 8,484
osteosarcoma 21 | 7,933
medulloblastoma, large-cell 20 | 6,234
psoriasis 18 | 6,685
Parkinson's disease 17 | 364
lung cancer 17 | 4,466
Cancer 16 | 2,346
atypical teratoid / rhabdoid tumor 16 | 4,369
glioblastoma 16 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,956
Alzheimer's disease 12 | 644
pediatric high grade glioma 12 | 2,712
Neurodegenerative disease 11 | 383
pilocytic astrocytoma 11 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
primitive neuroectodermal tumor 10 | 3,031
invasive ductal carcinoma 9 | 2,950
Breast cancer 8 | 3,094
group 3 medulloblastoma 8 | 2,254
lung adenocarcinoma 8 | 2,713
oligodendroglioma 8 | 2,849
ulcerative colitis 8 | 2,087
Brain disease 7 | 83
Nerve Degeneration 7 | 73
Parkinson Disease 7 | 102
Toxic encephalopathy 7 | 131
adrenocortical carcinoma 7 | 1,427
diabetes mellitus 7 | 1,663
interstitial cystitis 7 | 2,299
lung carcinoma 7 | 2,844
malignant mesothelioma 7 | 3,162
medulloblastoma 7 | 1,524
Dementia 6 | 129
Multiple myeloma 6 | 1,327
Multiple system atrophy 6 | 27
Parkinsonian Disorders 6 | 23
astrocytoma 6 | 1,493
group 4 medulloblastoma 6 | 1,875
non-small cell lung cancer 6 | 2,798
Pick disease 5 | 1,893
colon cancer 5 | 1,475
ependymoma 5 | 2,514
esophageal adenocarcinoma 5 | 737
juvenile dermatomyositis 5 | 1,189
pancreatic cancer 5 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic Lateral Sclerosis 4 | 431
Carcinoma 4 | 2,147
Dystonia 4 | 77
Endometriosis 4 | 535
Liver carcinoma 4 | 217
PARKINSON DISEASE, LATE-ONSET 4 | 18
Peripheral Neuropathy 4 | 303
Retinal detachment 4 | 33
active Crohn's disease 4 | 918
adult high grade glioma 4 | 2,148
aldosterone-producing adenoma 4 | 664
astrocytic glioma 4 | 2,241
atypical teratoid/rhabdoid tumor 4 | 1,095
breast carcinoma 4 | 1,614
ductal carcinoma in situ 4 | 1,745
glioblastoma multiforme 4 | 347
progressive supranuclear palsy 4 | 674
tuberculosis 4 | 1,557
Atopic dermatitis 3 | 944
Brain Ischemia 3 | 87
Celiac disease 3 | 112
Crohn's disease 3 | 304
Huntington's disease 3 | 72
Intellectual disability 3 | 573
Kidney disease 3 | 396
Myocardial Reperfusion Injury 3 | 34
REM sleep behavior disorder 3 | 16
Renal Cell Carcinoma 3 | 199
Rheumatoid Arthritis 3 | 1,160
Schizophrenia 3 | 501
Transient Ischemic Attack 3 | 10
Vascular disease 3 | 281
cutaneous lupus erythematosus 3 | 1,056
nephrosclerosis 3 | 329
nervous system disorder 3 | 53
non primary Sjogren syndrome sicca 3 | 840
pancreatic carcinoma 3 | 567
posterior fossa group A ependymoma 3 | 1,511
posterior fossa group B ependymoma 3 | 1,530
sonic hedgehog group medulloblastoma 3 | 1,482
tuberculosis and treatment for 6 months 3 | 686
Arthritis 2 | 248
Down syndrome 2 | 548
Hypertension 2 | 287
Inflammatory Bowel Diseases 2 | 87
Multiple Sclerosis 2 | 498
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 780
dermatomyositis 2 | 933
head and neck cancer 2 | 270
hepatocellular carcinoma 2 | 532
spina bifida 2 | 1,064

Tissue

Blood and immune system 38 | 17,995
Cardiovascular System 38 | 17,958
Digestive Tract 38 | 18,473
Endocrine System 38 | 18,512
Female tissues 38 | 18,647
Liver and Pancreas 38 | 18,136
Male tissues 38 | 17,969
Nervous System 38 | 18,561
Respiratory system 38 | 17,484
Skin and soft tissues 38 | 18,115
Urinary Tract 38 | 18,444

Target Family

Non-IDG 18 | 11,971
Enzyme 13 | 4,146
Kinase 6 | 634
GPCR 1 | 406
Transporter 1 | 473

WikiPathways Pathway

Parkinsons Disease Pathway 39 | 39
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-synuclein SNCA Tchem Non-IDG -3.59982 3997.3 1484
Mitogen-activated protein kinase 13 MAPK13 Tchem Kinase -2.46715 317.1 405
Cytochrome c CYCS Tbio Non-IDG -3.73952 4771.4 630
Synphilin-1 SNCAIP Tchem Non-IDG -2.02371 114.8 146
Ubiquitin-conjugating enzyme E2 G1 UBE2G1 Tbio Non-IDG -0.72379 5.55 133
Synaptotagmin-11 SYT11 Tbio Non-IDG -0.91695 10.8 115
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.55598 368.4 441
Polyubiquitin-B UBB Tbio Non-IDG 92.3 370
Caspase-2 CASP2 Tchem Enzyme -2.59829 416.4 493
Caspase-3 CASP3 Tchem Enzyme -4.25532 16628.4 1445