Development Level

Tbio 21 | 11,445
Tchem 14 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

short tibia 3 | 97
cardiovascular system phenotyp... 2 | 36
decreased bone mineral content 2 | 151
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
abnormal embryo size 1 | 220
abnormal lung morphology 1 | 26
abnormal pelvic girdle bone mo... 1 | 12
abnormal seminal vesicle morph... 1 | 114
abnormal spine curvature 1 | 9
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 82
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
small liver 1 | 8
small spleen 1 | 19
thrombocytopenia 1 | 56

Disease

ovarian cancer 26 | 8,520
Carcinoma 21 | 11,493
osteosarcoma 21 | 7,950
medulloblastoma, large-cell 20 | 6,241
group 3 medulloblastoma 19 | 4,104
Parkinson's disease 18 | 392
atypical teratoid / rhabdoid tumor 18 | 5,112
glioblastoma 18 | 5,792
lung cancer 18 | 4,740
psoriasis 18 | 6,694
Cancer 17 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
Alzheimer's disease 12 | 658
adult high grade glioma 12 | 3,801
Astrocytoma, Pilocytic 11 | 3,081
Neurodegenerative disease 11 | 414
Nerve Degeneration 10 | 121
Parkinsonian Disorders 10 | 56
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
primitive neuroectodermal tumor 10 | 3,035
Brain disease 9 | 96
Breast cancer 9 | 3,578
Schizophrenia 9 | 1,160
Toxic encephalopathy 9 | 141
ependymoma 9 | 4,679
invasive ductal carcinoma 9 | 2,951
lung adenocarcinoma 8 | 2,716
oligodendroglioma 8 | 2,850
Dementia 7 | 175
Multiple system atrophy 7 | 29
Muscle Rigidity 7 | 49
PARKINSON DISEASE 19, JUVENILE-ONSET 7 | 10
Parkinson Disease 7 | 64
Young onset Parkinson disease 7 | 10
adrenocortical carcinoma 7 | 1,428
diabetes mellitus 7 | 1,728
interstitial cystitis 7 | 2,312
lung carcinoma 7 | 2,843
malignant mesothelioma 7 | 3,232
Autosomal recessive predisposition 6 | 1,442
Bradykinesia 6 | 34
Dystonia 6 | 164
Multiple myeloma 6 | 1,332
PARKINSON DISEASE, LATE-ONSET 6 | 20
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
ulcerative colitis 6 | 1,819
Depressive disorder 5 | 409
Major Depressive Disorder 5 | 301
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
esophageal adenocarcinoma 5 | 737
juvenile dermatomyositis 5 | 1,187
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
Carcinoma, Hepatocellular 4 | 228
Constipation 4 | 181
Endometriosis 4 | 540
Kidney cancer 4 | 2,613
Liver carcinoma 4 | 240
Neurodegenerative Disorders 4 | 79
Postural instability 4 | 19
Progressive disorder 4 | 142
Retinal Detachment 4 | 51
Unipolar Depression 4 | 250
active Crohn's disease 4 | 922
aldosterone-producing adenoma 4 | 665
ductal carcinoma in situ 4 | 1,745
pediatric high grade glioma 4 | 1,064
progressive supranuclear palsy 4 | 676
tuberculosis 4 | 2,010
Alcoholic Intoxication, Chronic 3 | 289
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Blepharoptosis 3 | 231
Brain Ischemia 3 | 110
Dysarthria 3 | 192
Dyschezia 3 | 135
Dystonic disease 3 | 106
Huntington's disease 3 | 76
Hyperreflexia 3 | 209
Infantile onset 3 | 238
Kidney disease 3 | 430
Liver Cirrhosis, Experimental 3 | 769
Nervous System Diseases 3 | 53
Neuropathy 3 | 261
Tremor 3 | 113
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
cutaneous lupus erythematosus 3 | 1,057
medulloblastoma 3 | 720
nephrosclerosis 3 | 333
nervous system disorder 3 | 53
pancreatic carcinoma 3 | 562
tuberculosis and treatment for 6 months 3 | 409

Tissue

Endocrine System 38 | 18,159
Female tissues 38 | 17,400
Blood and immune system 37 | 16,909
Digestive Tract 37 | 17,369
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678
Respiratory system 36 | 16,393
Cardiovascular System 35 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 13 | 4,145
Kinase 6 | 634
GPCR 1 | 408
Transporter 1 | 473

WikiPathways Pathway

Parkinsons Disease Pathway 39 | 39
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caspase-2 CASP2 Tchem Enzyme -2.62373 431.8 571
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.59848 3752.4 324
Ubiquitin-conjugating enzyme E2 J2 UBE2J2 Tbio Non-IDG -0.52612 2.75 84
Caspase-6 CASP6 Tchem Enzyme -2.49135 293.6 874
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Aromatic-L-amino-acid decarboxylase DDC Tclin Enzyme -2.78263 593.3 412
Caspase-7 CASP7 Tchem Enzyme -2.69052 418.1 800