Development Level

Tbio 21 | 11,445
Tchem 16 | 1,598
Tclin 4 | 613

IMPC Phenotype

abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
decreased circulating sodium l... 2 | 22
increased circulating alkaline... 2 | 122
increased circulating free fat... 2 | 20
increased neutrophil cell numb... 2 | 46
preweaning lethality, complete... 2 | 979
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal skin condition 1 | 6
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
decreased T cell number 1 | 15
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased spleen weight 1 | 10
decreased thermal nociceptive ... 1 | 2
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged kidney 1 | 14
enlarged spleen 1 | 41
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Carcinoma 26 | 11,493
ovarian cancer 24 | 8,520
glioblastoma 23 | 5,792
Cancer 21 | 2,499
lung cancer 19 | 4,740
medulloblastoma, large-cell 19 | 6,241
psoriasis 19 | 6,694
osteosarcoma 17 | 7,950
subependymal giant cell astrocytoma 17 | 2,287
tuberculosis 16 | 2,010
Astrocytoma, Pilocytic 14 | 3,081
adult high grade glioma 13 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
invasive ductal carcinoma 13 | 2,951
Schizophrenia 12 | 1,160
adrenocortical carcinoma 12 | 1,428
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
ulcerative colitis 12 | 1,819
atypical teratoid / rhabdoid tumor 11 | 5,112
malignant mesothelioma 11 | 3,232
ependymoma 10 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
juvenile dermatomyositis 10 | 1,187
non-small cell lung cancer 10 | 2,890
Rheumatoid arthritis 9 | 1,191
acute quadriplegic myopathy 9 | 1,158
group 3 medulloblastoma 9 | 4,104
lung adenocarcinoma 9 | 2,716
lung carcinoma 9 | 2,843
Autosomal recessive predisposition 8 | 1,442
Liver Cirrhosis, Experimental 8 | 769
dermatomyositis 8 | 966
primary Sjogren syndrome 8 | 735
Brain Ischemia 7 | 110
Kidney cancer 7 | 2,613
Prostatic Neoplasms 7 | 495
Systemic lupus erythematosus 7 | 194
limb girdle muscular dystrophy 2A 7 | 213
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
Colonic Neoplasms 6 | 142
Complement deficiency 6 | 14
Duchenne muscular dystrophy 6 | 601
Hypersensitivity reaction type II disease 6 | 253
Melanoma 6 | 711
astrocytic glioma 6 | 2,597
astrocytoma 6 | 1,146
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
hepatocellular carcinoma 6 | 547
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
Adenocarcinoma 5 | 122
Alzheimer's disease 5 | 658
Arthritis 5 | 290
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
Immunologic Deficiency Syndromes 5 | 113
Kidney disease 5 | 430
Lung Neoplasms 5 | 232
Multiple myeloma 5 | 1,332
Nerve Degeneration 5 | 121
colon cancer 5 | 1,478
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
esophageal adenocarcinoma 5 | 737
gastric cancer 5 | 459
group 4 medulloblastoma 5 | 1,855
Arthritis, Rheumatoid 4 | 174
Asthma 4 | 385
Autoimmune Diseases 4 | 67
Becker muscular dystrophy 4 | 191
Breast Neoplasms 4 | 445
Breast cancer 4 | 3,578
Diarrhea 4 | 253
Endometriosis 4 | 540
Hypercalcemia 4 | 59
Lupus Erythematosus, Systemic 4 | 67
Mammary Neoplasms 4 | 425
Meningitis 4 | 67
Multiple Sclerosis 4 | 540
Obesity 4 | 678
Parkinson's disease 4 | 392
Pneumonia 4 | 174
Recurrent infections 4 | 48
Reperfusion Injury 4 | 86
Short stature 4 | 531
Splenomegaly 4 | 190
Stomach Neoplasms 4 | 300
Toxic encephalopathy 4 | 141
Vascular disease 4 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
breast carcinoma 4 | 1,638
gastric carcinoma 4 | 807
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
sonic hedgehog group medulloblastoma 4 | 467
Pick disease 3 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Cardiovascular System 40 | 15,192
Nervous System 39 | 16,725

Target Family

Non-IDG 24 | 12,091
Enzyme 8 | 4,145
Kinase 6 | 634
GPCR 2 | 408
Transcription Factor 1 | 1,400

WikiPathways Pathway

Oxidative Damage 41 | 41
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Complement C1q subcomponent subunit A C1QA Tbio Non-IDG -1.73823 51.2 241
Cyclin-dependent kinase inhibitor 1C CDKN1C Tbio Enzyme -2.81199 631.0 665
Cytochrome c CYCS Tbio Non-IDG -3.76637 4945.6 833
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Complement receptor type 2 CR2 Tbio Non-IDG -2.97911 940.3 934
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998
NF-kappa-B inhibitor epsilon NFKBIE Tbio Non-IDG -1.39025 20.6 313
Complement C4-B C4B Tbio Non-IDG -2.99381 1011.9 185
Complement C4-A C4B Tbio Non-IDG -3.04538 1109.8 297