Development Level

Tbio 27 | 10,625
Tchem 21 | 1,890
Tclin 10 | 602
Tdark 4 | 7,003

IMPC Term

decreased total body fat amoun... 3 | 186
abnormal bone structure 2 | 131
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased lean body mass 2 | 195
decreased mean platelet volume 2 | 12
improved glucose tolerance 2 | 56
increased circulating alkaline... 2 | 119
small kidney 2 | 10
abnormal behavior 1 | 226
abnormal clavicle morphology 1 | 5
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal cranium morphology 1 | 32
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 28
abnormal scapula morphology 1 | 3
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
absent mammary gland 1 | 1
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased skeletal muscle mass 1 | 1
decreased vertical activity 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased respiratory quotient 1 | 12
increased total body fat amoun... 1 | 57
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
shortened QRS complex duration 1 | 1
small heart 1 | 8
small ovary 1 | 1
small spleen 1 | 11
small uterus 1 | 1
thin skin 1 | 1

Disease

psoriasis 31 | 6,685
osteosarcoma 20 | 7,933
medulloblastoma, large-cell 19 | 6,234
ovarian cancer 19 | 8,484
Cancer 18 | 2,346
glioblastoma 17 | 5,572
lung cancer 16 | 4,466
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
interstitial cystitis 15 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
Prostatic Neoplasms 12 | 471
lung carcinoma 12 | 2,844
non-small cell lung cancer 12 | 2,798
atypical teratoid / rhabdoid tumor 11 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
lung adenocarcinoma 10 | 2,713
oligodendroglioma 10 | 2,849
Liver disease 9 | 219
group 4 medulloblastoma 9 | 1,875
pilocytic astrocytoma 9 | 3,086
Breast cancer 8 | 3,094
Hypertension 8 | 287
adrenocortical carcinoma 8 | 1,427
ependymoma 8 | 2,514
malignant mesothelioma 8 | 3,162
pediatric high grade glioma 8 | 2,712
primitive neuroectodermal tumor 8 | 3,031
Congenital adrenal hyperplasia 7 | 74
active Crohn's disease 7 | 918
chronic rhinosinusitis 7 | 512
ductal carcinoma in situ 7 | 1,745
pancreatic cancer 7 | 2,300
pituitary cancer 7 | 1,972
tuberculosis 7 | 1,557
Mammary Neoplasms 6 | 410
Methemoglobinemia 6 | 17
Pick disease 6 | 1,893
adult high grade glioma 6 | 2,148
astrocytic glioma 6 | 2,241
astrocytoma 6 | 1,493
cutaneous lupus erythematosus 6 | 1,056
diabetes mellitus 6 | 1,663
group 3 medulloblastoma 6 | 2,254
posterior fossa group A ependymoma 6 | 1,511
Adenocarcinoma 5 | 115
Adenoma 5 | 165
Antley-Bixler syndrome 5 | 15
Cholestasis 5 | 93
Drug-Induced Liver Injury 5 | 118
Endometriosis 5 | 535
Lung Neoplasms 5 | 171
Obesity 5 | 616
Peripheral Neuropathy 5 | 303
cystic fibrosis 5 | 1,665
invasive ductal carcinoma 5 | 2,950
ulcerative colitis 5 | 2,087
Adrenal cortical adenoma 4 | 10
Adverse reaction to drug 4 | 54
Atopic dermatitis 4 | 944
Candidiasis of mouth 4 | 5
Candidiasis of skin 4 | 6
Cushing's syndrome 4 | 47
Human immunodeficiency virus infection 4 | 6
Pityriasis versicolor 4 | 18
Polycystic Ovary Syndrome 4 | 332
Rheumatoid Arthritis 4 | 1,160
Schizophrenia 4 | 501
Tinea corporis 4 | 25
Tinea cruris 4 | 12
Tinea pedis 4 | 30
adrenocortical adenoma 4 | 134
aldosterone-producing adenoma 4 | 664
breast carcinoma 4 | 1,614
fibroadenoma 4 | 557
non primary Sjogren syndrome sicca 4 | 840
substance-related disorder 4 | 105
Acute kidney injury 3 | 65
Alzheimer's disease 3 | 644
Atrial Fibrillation 3 | 110
Colorectal Neoplasms 3 | 217
Epilepsy 3 | 346
Hyperandrogenism 3 | 32
Hypercortisolism 3 | 8
Infertility 3 | 163
Kidney disease 3 | 396
Liver carcinoma 3 | 217
Malaria 3 | 140
Male infertility 3 | 170
Prostate cancer 3 | 172
cystic fibrosis and chronic rhinosinusitis 3 | 213
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 832
gliosarcoma 3 | 19
head and neck cancer and chronic obstructive pulmonary disease 3 | 237
juvenile dermatomyositis 3 | 1,189
medulloblastoma 3 | 1,524
nephrosclerosis 3 | 329
primary pancreatic ductal adenocarcinoma 3 | 1,271
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Digestive Tract 61 | 18,473
Endocrine System 61 | 18,512
Female tissues 61 | 18,647
Liver and Pancreas 61 | 18,136
Nervous System 61 | 18,561
Skin and soft tissues 61 | 18,115
Urinary Tract 61 | 18,444
Blood and immune system 60 | 17,995
Cardiovascular System 60 | 17,958
Male tissues 59 | 17,969
Respiratory system 59 | 17,484

Target Family

Non-IDG 34 | 11,971
Enzyme 28 | 4,146

WikiPathways Pathway

Oxidation by Cytochrome P450 62 | 62
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
24-hydroxycholesterol 7-alpha-hydroxylase CYP39A1 Tbio Enzyme -0.95411 6.43 97
Cytochrome b5 CYB5A Tchem Non-IDG -3.24788 1711.2 249
Cytochrome P450 4V2 CYP4V2 Tbio Non-IDG -2.66290 481.8 87
Cytochrome P450 4F22 CYP4F22 Tbio Non-IDG -1.98060 100.6 25
NADH-cytochrome b5 reductase 3 CYB5R3 Tchem Enzyme -1.93440 89.2 241
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 Tchem Enzyme -2.65191 464.3 66
Cytochrome P450 4B1 CYP4B1 Tbio Non-IDG -1.77340 65.4 88
Cytochrome P450 11B1, mitochondrial CYP11B1 Tclin Enzyme -2.62509 411.6 105
Cytochrome P450 2S1 CYP2S1 Tbio Non-IDG -1.30029 25.6 139
Putative inactive cytochrome P450 2G1 CYP2G1P Tdark Non-IDG 0.00000 0