Development Level

Tbio 28 | 11,178
Tchem 22 | 1,885
Tclin 9 | 612
Tdark 3 | 6,569

IMPC Phenotype

decreased total body fat amoun... 3 | 207
increased circulating alkaline... 3 | 122
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating phosphat... 2 | 27
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
small kidney 2 | 16
abnormal clavicle morphology 1 | 6
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal male genitalia morpho... 1 | 3
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 10
abnormal scapula morphology 1 | 3
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
absent mammary gland 1 | 1
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased skeletal muscle mass 1 | 1
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 38
increased circulating unsatura... 1 | 1
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
oligodactyly 1 | 1
polydactyly 1 | 7
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small heart 1 | 10
small ovary 1 | 1
small spleen 1 | 19
small uterus 1 | 3
thin skin 1 | 2

Disease

Carcinoma 48 | 11,192
psoriasis 31 | 6,514
Cancer 20 | 2,388
osteosarcoma 20 | 7,766
medulloblastoma, large-cell 19 | 6,086
ovarian cancer 19 | 8,297
glioblastoma 17 | 5,635
lung cancer 17 | 4,607
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,911
interstitial cystitis 15 | 2,237
ependymoma 14 | 4,559
Autosomal recessive predisposition 13 | 1,407
Prostatic Neoplasms 13 | 472
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,204
non-small cell lung cancer 13 | 2,799
atypical teratoid / rhabdoid tumor 12 | 4,971
group 3 medulloblastoma 12 | 4,002
lung carcinoma 12 | 2,755
adult high grade glioma 11 | 3,701
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,872
Breast cancer 10 | 3,469
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,902
lung adenocarcinoma 10 | 2,627
oligodendroglioma 10 | 2,768
Astrocytoma, Pilocytic 9 | 3,006
Hypertension 9 | 372
Liver disease 9 | 227
Chemical and Drug Induced Liver Injury 8 | 188
Osteoporosis 8 | 348
adrenocortical carcinoma 8 | 1,385
malignant mesothelioma 8 | 3,135
primitive neuroectodermal tumor 8 | 2,957
tuberculosis 8 | 1,963
Breast Neoplasms 7 | 423
Congenital adrenal hyperplasia 7 | 71
Mammary Neoplasms 7 | 403
Obesity 7 | 655
Schizophrenia 7 | 1,136
active Crohn's disease 7 | 882
astrocytic glioma 7 | 2,530
chronic rhinosinusitis 7 | 505
ductal carcinoma in situ 7 | 1,686
pancreatic cancer 7 | 2,322
pituitary cancer 7 | 1,915
Cholestasis 6 | 154
Delayed bone age 6 | 132
Methemoglobinemia 6 | 16
Pick disease 6 | 1,856
cutaneous lupus erythematosus 6 | 1,016
cystic fibrosis 6 | 1,629
diabetes mellitus 6 | 1,683
Adenocarcinoma 5 | 116
Adenoma 5 | 159
Antley-Bixler syndrome 5 | 16
Cryptorchidism 5 | 287
Cushing's syndrome 5 | 47
Drug-Related Side Effects and Adverse Reactions 5 | 61
Endometriosis 5 | 521
Enlarged polycystic ovaries 5 | 10
Failure to gain weight 5 | 359
Lung Neoplasms 5 | 217
Melanoma 5 | 689
Pediatric failure to thrive 5 | 359
Polycystic ovary syndrome 5 | 348
Short stature 5 | 514
Small testicle 5 | 69
astrocytoma 5 | 1,113
group 4 medulloblastoma 5 | 1,806
invasive ductal carcinoma 5 | 2,867
ulcerative colitis 5 | 1,765
Abnormality of metabolism/homeostasis 4 | 133
Adrenal cortical adenoma 4 | 18
Adverse reaction to drug 4 | 60
Atopic dermatitis 4 | 915
Atrial Fibrillation 4 | 120
Epilepsy 4 | 775
Fatty Liver 4 | 69
Growth delay 4 | 112
Growth failure 4 | 112
Growth retardation 4 | 113
Hepatomegaly 4 | 280
Hyperaldosteronism 4 | 33
Increased circulating ACTH level 4 | 8
Liver Cirrhosis 4 | 173
Low to undetectable plasma cortisol 4 | 11
Malaria 4 | 155
Male Pseudohermaphroditism 4 | 17
Male infertility 4 | 199
Pityriasis versicolor 4 | 19
Poor growth 4 | 112
Rheumatoid arthritis 4 | 1,156
Tinea corporis 4 | 25
Tinea pedis 4 | 29
Very poor growth 4 | 112
adrenocortical adenoma 4 | 127
aldosterone-producing adenoma 4 | 646
breast carcinoma 4 | 1,589
fibroadenoma 4 | 538
head and neck cancer and chronic obstructive pulmonary disease 4 | 226
substance-related disorder 4 | 156

Tissue

Endocrine System 58 | 18,159
Digestive Tract 57 | 17,369
Female tissues 56 | 17,400
Liver and Pancreas 55 | 16,750
Male tissues 54 | 17,142
Skin and soft tissues 54 | 17,230
Urinary Tract 51 | 16,678
Blood and immune system 50 | 16,909
Respiratory system 50 | 16,393
Nervous System 46 | 16,725
Cardiovascular System 33 | 15,192

Target Family

Non-IDG 34 | 12,091
Enzyme 28 | 4,145

WikiPathways Pathway

Oxidation by Cytochrome P450 62 | 62
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome P450 2A13 CYP2A13 Tbio Non-IDG -2.14858 139.9 122
Cytochrome b5 reductase 4 CYB5R4 Tbio Enzyme -1.15554 17.5 107
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.65839 4688.0 397
Cytochrome P450 1B1 CYP1B1 Tchem Non-IDG -2.93702 904.4 260
Vitamin D 25-hydroxylase CYP2R1 Tbio Enzyme -1.96830 95.4 152
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369
Phylloquinone omega-hydroxylase CYP4F2 CYP4F2 Tbio Enzyme -2.16137 145.5 83
Cytochrome P450 3A43 CYP3A43 Tclin Enzyme -1.21436 15.2 80
Cytochrome P450 4A11 CYP4A11 Tbio Non-IDG -1.97180 93.7 142
Cytochrome P450 26A1 CYP26A1 Tchem Enzyme -2.44772 290.1 197