Development Level

Tbio 7 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

decreased prepulse inhibition 1 | 82
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating sodium l... 1 | 71
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Cancer 12 | 2,499
Carcinoma 10 | 11,493
osteosarcoma 9 | 7,950
ovarian cancer 9 | 8,520
Arthritis 8 | 290
Autosomal recessive predisposition 7 | 1,442
Osteoporosis 7 | 363
pancreatic cancer 7 | 2,398
Osteopetrosis 6 | 43
diabetes mellitus 6 | 1,728
glioblastoma 6 | 5,792
lung cancer 6 | 4,740
tuberculosis 6 | 2,010
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Hypercalcemia 5 | 59
Kidney disease 5 | 430
Lytic lesion 5 | 32
Osteonecrosis 5 | 27
Root resorption 5 | 22
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
periodontitis 5 | 293
psoriasis 5 | 6,694
ulcerative colitis 5 | 1,819
Hyperparathyroidism 4 | 48
Multiple Sclerosis 4 | 540
adult high grade glioma 4 | 3,801
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
Anemia 3 | 365
Atherosclerosis 3 | 291
Bone pain 3 | 42
Bowing of the long bones 3 | 31
Coronary artery disease 3 | 268
Frequent fractures 3 | 53
Heart disease 3 | 306
Hemoglobin low 3 | 124
Hypersensitivity reaction type II disease 3 | 253
Increased fracture rate 3 | 53
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Obesity 3 | 678
Osteolysis 3 | 7
Osteomyelitis 3 | 42
Paget's disease of bone 3 | 36
Pneumonia 3 | 174
Schizophrenia 3 | 1,160
Short stature 3 | 531
Thrombocytopenia 3 | 197
Varying degree of multiple fractures 3 | 53
atypical teratoid / rhabdoid tumor 3 | 5,112
cystic fibrosis 3 | 1,696
invasive ductal carcinoma 3 | 2,951
medulloblastoma, large-cell 3 | 6,241
non primary Sjogren syndrome sicca 3 | 891
pituitary cancer 3 | 1,972
Big calvaria 2 | 147
Breast Neoplasms 2 | 445
Cerebrovascular disease 2 | 238
Congenital deafness 2 | 185
Deafness 2 | 198
Decreased platelet count 2 | 111
Down syndrome 2 | 499
Dysarthria 2 | 192
Encephalitis 2 | 64
Hearing Loss, Partial 2 | 185
Hepatitis C 2 | 94
Hepatomegaly 2 | 285
Hyperalgesia 2 | 83
Hypertension 2 | 396
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Influenza 2 | 142
Leukemia, Lymphocytic, Chronic, B-Cell 2 | 34
Liver disease 2 | 237
Lung disease 2 | 142
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Myocardial Infarction 2 | 151
Parkinson's disease 2 | 392
Progressive disorder 2 | 142
Purpura 2 | 43
Recurrent respiratory infections 2 | 141
Reperfusion Injury 2 | 86
Rickets 2 | 49
Seizures 2 | 596
Tremor 2 | 113
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
hearing impairment 2 | 199
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Female tissues 14 | 17,400
Nervous System 14 | 16,725
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 8 | 12,091
Enzyme 4 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634
Transporter 1 | 473

WikiPathways Pathway

Osteoclast Signaling 16 | 16
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Sodium/hydrogen exchanger 1 SLC9A1 Tchem Transporter -2.93178 921.2 198
Tumor necrosis factor receptor superfamily member 11B TNFRSF11B Tbio Non-IDG -3.31331 1624.0 536
Ovarian cancer G-protein coupled receptor 1 GPR68 Tchem GPCR -1.67161 53.3 180
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 AIMP2 Tbio Enzyme -1.35413 26.1 138
Tartrate-resistant acid phosphatase type 5 ACP5 Tbio Enzyme -3.35274 1913.6 333
Interferon beta IFNB1 Tbio Non-IDG -3.83887 6789.5 731
Platelet-derived growth factor subunit B PDGFB Tchem Non-IDG -3.27151 1795.5 434
Osteopontin SPP1 Tbio Non-IDG -3.66384 4916.5 1053
V-type proton ATPase subunit G 1 ATP6V1G1 Tbio Enzyme -0.84169 6.43 112