Development Level

Tbio 37 | 11,445
Tchem 9 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 2 | 298
abnormal retina morphology 2 | 71
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
increased bone mineral content 2 | 108
increased lean body mass 2 | 172
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
absent optic nerve 1 | 2
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating insulin ... 1 | 76
decreased granulocyte number 1 | 6
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

Carcinoma 31 | 11,493
ovarian cancer 26 | 8,520
osteosarcoma 25 | 7,950
psoriasis 21 | 6,694
lung cancer 19 | 4,740
medulloblastoma, large-cell 19 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Cancer 16 | 2,499
atypical teratoid / rhabdoid tumor 16 | 5,112
non-small cell lung cancer 16 | 2,890
Autosomal recessive predisposition 15 | 1,442
Schizophrenia 15 | 1,160
glioblastoma 15 | 5,792
invasive ductal carcinoma 15 | 2,951
ependymoma 13 | 4,679
group 3 medulloblastoma 13 | 4,104
pancreatic cancer 12 | 2,398
Breast cancer 11 | 3,578
ductal carcinoma in situ 11 | 1,745
lung adenocarcinoma 11 | 2,716
malignant mesothelioma 11 | 3,232
oligodendroglioma 11 | 2,850
lung carcinoma 10 | 2,843
Astrocytoma, Pilocytic 9 | 3,081
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
diabetes mellitus 9 | 1,728
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
Down syndrome 8 | 499
Epilepsy 8 | 792
Pick disease 8 | 1,894
Seizures 8 | 596
adrenocortical carcinoma 8 | 1,428
adult high grade glioma 8 | 3,801
breast carcinoma 8 | 1,638
interstitial cystitis 8 | 2,312
pituitary cancer 8 | 1,972
ulcerative colitis 8 | 1,819
Anemia 7 | 365
Chemical and Drug Induced Liver Injury 7 | 195
Cleft Palate 7 | 271
Hypertension 7 | 396
Mental Depression 7 | 333
Multiple myeloma 7 | 1,332
cystic fibrosis 7 | 1,696
fibroadenoma 7 | 559
Bipolar Disorder 6 | 666
Cleft Lip 6 | 141
Depressive disorder 6 | 409
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
Diabetes Mellitus, Type 2 6 | 142
Intellectual disability 6 | 1,016
Lung Neoplasms 6 | 232
Rheumatoid arthritis 6 | 1,191
astrocytic glioma 6 | 2,597
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
hepatocellular carcinoma 6 | 547
nasopharyngeal carcinoma 6 | 1,058
non primary Sjogren syndrome sicca 6 | 891
pancreatic carcinoma 6 | 562
spina bifida 6 | 1,074
Alzheimer's disease 5 | 658
Atherosclerosis 5 | 291
Contact Dermatitis 5 | 81
Dermatitis, Contact 5 | 71
Dull intelligence 5 | 645
Fatty Liver 5 | 70
Homocystinuria 5 | 21
Hyperhomocysteinemia 5 | 37
Hypertensive disease 5 | 292
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Prostatic Neoplasms 5 | 495
Toxic encephalopathy 5 | 141
Vascular disease 5 | 319
Waldenstrons macroglobulinemia 5 | 765
acute quadriplegic myopathy 5 | 1,158
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 807
primary pancreatic ductal adenocarcinoma 5 | 1,109
progressive supranuclear palsy 5 | 676
Atopic dermatitis 4 | 952
Brain Ischemia 4 | 110
Infertility, Male 4 | 46
Kidney cancer 4 | 2,613
Liver carcinoma 4 | 240
Major Depressive Disorder 4 | 301
Male infertility 4 | 206
aldosterone-producing adenoma 4 | 665
gastric cancer 4 | 459
nephrosclerosis 4 | 333
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735

Tissue

Digestive Tract 49 | 17,369
Endocrine System 49 | 18,159
Liver and Pancreas 49 | 16,750
Male tissues 49 | 17,142
Nervous System 49 | 16,725
Skin and soft tissues 49 | 17,230
Urinary Tract 48 | 16,678
Female tissues 47 | 17,400
Blood and immune system 46 | 16,909
Respiratory system 46 | 16,393
Cardiovascular System 43 | 15,192

Target Family

Enzyme 45 | 4,145
Kinase 4 | 634
Epigenetic 1 | 242
Non-IDG 1 | 12,091

WikiPathways Pathway

One carbon metabolism and rela... 51 | 51
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sarcosine dehydrogenase, mitochondrial SARDH Tbio Enzyme -1.78290 56.5 35
Cysteine sulfinic acid decarboxylase CSAD Tbio Enzyme -2.16604 143.8 134
Choline-phosphate cytidylyltransferase B PCYT1B Tbio Enzyme -1.46937 28.8 40
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Methionine synthase MTR Tbio Enzyme -2.56900 300.2 87
Glycine N-methyltransferase GNMT Tbio Enzyme -1.56517 40.8 216
Cholinephosphotransferase 1 CHPT1 Tbio Enzyme -1.42313 23.5 80
Ethanolamine kinase 1 ETNK1 Tbio Kinase -1.59702 38.8 152
Dimethylglycine dehydrogenase, mitochondrial DMGDH Tbio Enzyme -1.39556 25.3 115
Choline-phosphate cytidylyltransferase A PCYT1A Tbio Enzyme -2.39713 242.7 191