Development Level

Tbio 23 | 10,625
Tchem 15 | 1,890
Tclin 3 | 602

IMPC Term

abnormal snout morphology 1 | 18
decreased caudal vertebrae num... 1 | 49
decreased circulating glucose ... 1 | 121
decreased neutrophil cell numb... 1 | 37
increased grip strength 1 | 83
male infertility 1 | 62
preweaning lethality, complete... 1 | 633

Disease

osteosarcoma 21 | 7,933
ovarian cancer 21 | 8,492
psoriasis 20 | 6,685
Cancer 15 | 2,346
glioblastoma 14 | 5,572
lung carcinoma 14 | 2,844
lung cancer 13 | 4,473
pancreatic cancer 12 | 2,300
malignant mesothelioma 11 | 3,163
subependymal giant cell astrocytoma 11 | 2,287
ulcerative colitis 11 | 2,087
non-small cell lung cancer 10 | 2,798
Breast cancer 9 | 3,099
Carcinoma 9 | 2,147
cystic fibrosis 9 | 1,670
medulloblastoma, large-cell 9 | 6,234
pilocytic astrocytoma 9 | 3,086
tuberculosis 9 | 1,563
Arthritis 8 | 248
invasive ductal carcinoma 8 | 2,950
Inflammatory bowel disease 7 | 142
Muckle-Wells syndrome 7 | 11
Multiple myeloma 7 | 1,328
adult high grade glioma 7 | 2,148
gastric cancer 7 | 436
interstitial cystitis 7 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
lung adenocarcinoma 7 | 2,714
pancreatic carcinoma 7 | 567
pediatric high grade glioma 7 | 2,712
Blau syndrome 6 | 8
Crohn's disease 6 | 304
Mammary Neoplasms 6 | 410
Rheumatoid Arthritis 6 | 1,171
cutaneous lupus erythematosus 6 | 1,056
diabetes mellitus 6 | 1,663
hepatocellular carcinoma 6 | 550
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
juvenile dermatomyositis 6 | 1,189
primary Sjogren syndrome 6 | 789
primary pancreatic ductal adenocarcinoma 6 | 1,271
Atherosclerosis 5 | 275
Brain Ischemia 5 | 87
IGA Glomerulonephritis 5 | 454
Kidney disease 5 | 397
Myocardial Reperfusion Injury 5 | 34
Obesity 5 | 616
Peritonitis 5 | 37
Waldenstrons macroglobulinemia 5 | 765
atypical teratoid / rhabdoid tumor 5 | 4,369
colon cancer 5 | 1,475
sarcoidosis 5 | 368
Dermatitis 4 | 141
Exanthem 4 | 39
Liver carcinoma 4 | 217
Lung Neoplasms 4 | 171
Lung disease 4 | 136
Mevalonic aciduria 4 | 12
Pneumonia 4 | 133
Urticaria 4 | 53
Vascular disease 4 | 281
active Crohn's disease 4 | 918
astrocytoma 4 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
oligodendroglioma 4 | 2,849
posterior fossa group A ependymoma 4 | 1,511
Adenocarcinoma 3 | 115
Amyloidosis 3 | 68
Amyotrophic Lateral Sclerosis 3 | 432
Asthma 3 | 349
Calcinosis 3 | 63
Candidiasis 3 | 48
Colitis 3 | 46
Contact Dermatitis 3 | 80
Crohn Disease 3 | 97
Eye disease 3 | 55
Familial Mediterranean fever 3 | 12
Gout 3 | 93
Heart valve disease 3 | 24
Hypersensitivity 3 | 63
Hypersensitivity reaction type II disease 3 | 235
Inflammation 3 | 109
Neoplasm Metastasis 3 | 138
Neurodegenerative disease 3 | 383
Reperfusion Injury 3 | 84
Stomach Neoplasms 3 | 282
Toxic encephalopathy 3 | 131
Tularemia 3 | 22
acute myeloid leukemia 3 | 785
adrenocortical carcinoma 3 | 1,427
ependymoma 3 | 2,514
esophageal adenocarcinoma 3 | 737
group 3 medulloblastoma 3 | 2,254
group 4 medulloblastoma 3 | 1,875
medulloblastoma 3 | 1,524
mucosa-associated lymphoid tissue lymphoma 3 | 480
Coronary artery disease 2 | 240
Peripheral Neuropathy 2 | 303
Vasculitis 2 | 64
head and neck cancer 2 | 270

Tissue

Blood and immune system 41 | 17,995
Cardiovascular System 41 | 17,958
Digestive Tract 41 | 18,473
Endocrine System 41 | 18,512
Female tissues 41 | 18,647
Male tissues 41 | 17,969
Nervous System 41 | 18,561
Urinary Tract 41 | 18,444
Skin and soft tissues 40 | 18,115
Liver and Pancreas 39 | 18,136
Respiratory system 39 | 17,484

Target Family

Non-IDG 23 | 11,969
Enzyme 12 | 4,146
Kinase 4 | 634
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400

WikiPathways Pathway

Nucleotide-binding Oligomeriza... 41 | 41
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NACHT, LRR and PYD domains-containing protein 10 NLRP10 Tbio Non-IDG -1.30183 21.3 121
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.22772 1655.7 459
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.11206 1371.9 332
Caspase-8 CASP8 Tchem Enzyme -3.51864 2954.7 930
NACHT, LRR and PYD domains-containing protein 7 NLRP7 Tbio Non-IDG -1.60000 0.00000 78
NF-kappa-B essential modulator IKBKG Tchem Kinase -3.05271 1121.7 849
Angio-associated migratory cell protein AAMP Tbio Non-IDG -1.48321 30.4 112
NACHT, LRR and PYD domains-containing protein 2 NLRP2 Tbio Non-IDG -1.81402 65.6 220
Protein SGT1 homolog SUGT1 Tbio Non-IDG -0.79781 9.74 167
E3 ubiquitin-protein ligase XIAP XIAP Tchem Enzyme -3.10589 1302.7 462