Development Level

Tchem 7 | 1,598
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

convulsive seizures 1 | 13
decreased grip strength 1 | 116
decreased total body fat amoun... 1 | 207
decreased urine magnesium leve... 1 | 3
increased fasted circulating g... 1 | 76
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 9 | 11,493
Asthma 5 | 385
Vascular disease 5 | 319
Acute exacerbation of asthma 4 | 14
Allergic rhinitis 4 | 94
Asthma management 4 | 19
Asthma night-time symptoms 4 | 7
Asthma-chronic obstructive pulmonary disease overlap syndrome 4 | 7
Bronchitis 4 | 43
Bronchospasm 4 | 9
COPD Associated with Chronic Bronchitis 4 | 11
Chronic Obstructive Pulmonary Disease with Bronchospasms 4 | 8
Common cold 4 | 67
Disorder of lung 4 | 7
Dysmenorrhea 4 | 21
Influenza-like symptoms 4 | 16
Nasal congestion 4 | 21
Nasal discharge 4 | 24
Pain 4 | 103
Pulmonary emphysema 4 | 48
Sinus headache 4 | 16
Spasticity 4 | 26
ependymoma 4 | 4,679
tuberculosis 4 | 2,010
Apnea in the newborn 3 | 3
Astrocytoma, Pilocytic 3 | 3,081
Backache 3 | 8
Cluster Headache Prevention 3 | 6
Cluster headache syndrome 3 | 8
Headache disorder 3 | 19
Joint pain 3 | 8
Migraine 3 | 83
Myocardial Perfusion Imaging Adjunct 3 | 25
Paroxysmal supraventricular tachycardia 3 | 12
Tension-type headache 3 | 10
Vascular headache 3 | 7
adult high grade glioma 3 | 3,801
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
Adverse reaction to drug 2 | 61
Depressive disorder 2 | 409
Drug Hypersensitivity 2 | 34
Drug allergy 2 | 36
Drug-Related Side Effects and Adverse Reactions 2 | 62
Epilepsy 2 | 792
Genetic Predisposition to Disease 2 | 27
Hypertrophic cardiomyopathy 20 2 | 12
Hypotension 2 | 82
Ischemia 2 | 28
Liver Cirrhosis, Experimental 2 | 769
Myocardial Infarction 2 | 151
Reperfusion Injury 2 | 86
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Sepsis 2 | 24
Substance Withdrawal Syndrome 2 | 55
Ventricular Dysfunction 2 | 7
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
cutaneous lupus erythematosus 2 | 1,057
interstitial cystitis 2 | 2,312
lung adenocarcinoma 2 | 2,716
ovarian cancer 2 | 8,520
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Actinic keratosis 1 | 21
Anogenital venereal wart 1 | 14
Anxiety Disorders 1 | 38
Benign paroxysmal positional nystagmus 1 | 11
Bradycardia 1 | 36
Catalepsy 1 | 15
Coarse hair 1 | 31
Dry eye syndrome 1 | 18
Fine hair 1 | 42
Gaucher disease type 3 1 | 67
Human immunodeficiency virus infectious disease 1 | 138
Hyperactive behavior 1 | 91
Hyperkinesis 1 | 32
Hypertensive disorder 1 | 56
Hypotrichosis of the scalp 1 | 6
Infarction, Middle Cerebral Artery 1 | 33
Panic disorder 1 | 61
Papillary thyroid carcinoma 1 | 43
Psychoses, Substance-Induced 1 | 17
Rough hair texture 1 | 31
Sparse body hair 1 | 32
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Subarachnoid Hemorrhage 1 | 7
Tear film insufficiency 1 | 15
Tetanus 1 | 68
Weight Loss 1 | 24
inflammatory breast cancer 1 | 286

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Male tissues 11 | 17,142
Skin and soft tissues 11 | 17,230
Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Liver and Pancreas 10 | 16,750
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Urinary Tract 10 | 16,678

Target Family

GPCR 11 | 408

WikiPathways Pathway

Nucleotide GPCRs 11 | 11
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
P2Y purinoceptor 2 P2RY2 Tclin GPCR -2.74629 565.7 192
P2Y purinoceptor 4 P2RY4 Tchem GPCR -1.85746 67.8 189
P2Y purinoceptor 6 P2RY6 Tchem GPCR -1.99873 102.6 191
Adenosine receptor A1 ADORA1 Tclin GPCR -3.08657 1177.9 342
Lysophosphatidic acid receptor 4 LPAR4 Tchem GPCR -1.38205 22.6 190
Adenosine receptor A3 ADORA3 Tchem GPCR -2.39734 255.0 54
Leukotriene B4 receptor 1 LTB4R Tchem GPCR -2.74171 557.6 365
Adenosine receptor A2b ADORA2B Tclin GPCR -2.05073 105.4 198
Adenosine receptor A2a ADORA2A Tclin GPCR -2.98333 954.1 244
Lysophosphatidic acid receptor 6 LPAR6 Tchem GPCR -1.51557 35.0 109