Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598

Disease

Cancer 5 | 2,499
Carcinoma 5 | 11,493
Severe combined immunodeficiency 5 | 51
osteosarcoma 5 | 7,950
Ataxia telangiectasia 4 | 34
Microcephaly 4 | 166
Nijmegen breakage syndrome 4 | 24
Werner syndrome 4 | 29
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
Autosomal recessive predisposition 3 | 1,442
DNA ligase IV deficiency 3 | 7
Kidney cancer 3 | 2,613
Small head 3 | 374
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
glioblastoma 3 | 5,792
medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
Adenocarcinoma of lung 2 | 142
Disease Models, Animal 2 | 155
Dull intelligence 2 | 645
Dysarthria 2 | 192
Dysdiadochokinesis 2 | 25
Hereditary Breast and Ovarian Cancer Syndrome 2 | 14
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Poor school performance 2 | 645
Short stature 2 | 531
Systemic lupus erythematosus 2 | 194
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
ependymoma 2 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
primitive neuroectodermal tumor 2 | 3,035
Abnormal visual pursuit 1 | 14
Abnormality of lipid metabolism 1 | 9
Acanthosis Nigricans 1 | 27
Acute blood cancer 1 | 6
Acute leukemia 1 | 15
Broad nasal tip 1 | 28
Broad-based gait 1 | 19
Carcinoma, Squamous Cell 1 | 110
Cerebellar Dysmetria 1 | 56
Chemical and Drug Induced Liver Injury 1 | 195
Chromosome Aberrations 1 | 16
Chromosome Breakage 1 | 36
Coloboma 1 | 51
Congenital hypoplasia of kidney 1 | 32
Convex nasal bridge 1 | 57
Convex nasal ridge 1 | 37
Cortical gyral simplification 1 | 19
Dilated ventricles (finding) 1 | 121
Distal amyotrophy 1 | 51
Dyslipidemias 1 | 27
Enophthalmos 1 | 75
Erythema 1 | 58
Flushing 1 | 60
Frequent falls 1 | 12
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Hepatic encephalopathy 1 | 27
High forehead 1 | 102
High pitched voice 1 | 23
Hyperopia 1 | 70
Hyperplasia of malar bones 1 | 4
Hypertriglyceridemia result 1 | 37
Impaired smooth pursuit 1 | 14
Increased chromosomal breakage 1 | 27
Insulin Resistance 1 | 72
Isolated growth hormone deficiency 1 | 30
Lung diseases 1 | 50
Lymphoma 1 | 81
Lymphopenia 1 | 67
Nystagmus, End-Position 1 | 12
Photosensitivity of skin 1 | 51
Poor growth 1 | 114
Prominent midface 1 | 4
Prominent nasal bridge 1 | 57
Sensory neuropathy 1 | 20
Short lower third of face 1 | 9
Small chin 1 | 9
Spider Veins 1 | 17
Squamous cell carcinoma 1 | 129
Steatohepatitis 1 | 44
Sunken eyes 1 | 63
Tall forehead 1 | 102
Telangiectasis 1 | 36
Unilateral agenesis of kidney 1 | 20
Very poor growth 1 | 114
Xeroderma pigmentosum 1 | 43
Xeroderma pigmentosum group D 1 | 33
Xeroderma pigmentosum variant type 1 | 4

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 6 | 12,091
Kinase 1 | 634

WikiPathways Pathway

Non-homologous end joining 7 | 7
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Non-homologous end-joining factor 1 NHEJ1 Tbio Non-IDG -1.93558 91.5 270
DNA repair protein XRCC4 XRCC4 Tbio Non-IDG -2.38352 232.9 322
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.68622 470.8 874
DNA-dependent protein kinase catalytic subunit PRKDC Tchem Kinase -2.85973 723.4 1160
Double-strand break repair protein MRE11 MRE11 Tbio Non-IDG -2.02762 98.5 459
X-ray repair cross-complementing protein 6 XRCC6 Tbio Non-IDG -2.86424 688.3 865
DNA repair protein RAD50 RAD50 Tbio Non-IDG -1.42369 23.8 305