Development Level

Tbio 13 | 11,651
Tclin 12 | 612
Tchem 7 | 1,388

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
abnormal embryo size 1 | 220
abnormal hair growth 1 | 10
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal testis morphology 1 | 43
decreased circulating creatine... 1 | 4
decreased lymphocyte cell numb... 1 | 83
edema 1 | 59
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating glycerol... 1 | 9
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979
small heart 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytosis 1 | 27

Disease

Carcinoma 25 | 11,493
Schizophrenia 18 | 1,160
glioblastoma 16 | 5,792
osteosarcoma 15 | 7,950
ovarian cancer 15 | 8,520
psoriasis 15 | 6,694
atypical teratoid / rhabdoid tumor 14 | 5,112
ependymoma 14 | 4,679
Depressive disorder 13 | 409
lung cancer 13 | 4,740
Astrocytoma, Pilocytic 12 | 3,081
Cancer 12 | 2,499
medulloblastoma, large-cell 12 | 6,241
Mental Depression 11 | 333
group 3 medulloblastoma 11 | 4,104
Alzheimer's disease 10 | 658
Attention deficit hyperactivity disorder 10 | 278
Bipolar Disorder 10 | 666
Breast cancer 10 | 3,578
Major Depressive Disorder 10 | 301
Parkinson's disease 10 | 392
Seizures 10 | 596
adult high grade glioma 10 | 3,801
malignant mesothelioma 10 | 3,232
primitive neuroectodermal tumor 10 | 3,035
Hypertension 9 | 396
Mood Disorders 9 | 184
Unipolar Depression 9 | 250
interstitial cystitis 9 | 2,312
lung adenocarcinoma 9 | 2,716
lung carcinoma 9 | 2,843
oligodendroglioma 9 | 2,850
Alcoholic Intoxication, Chronic 8 | 289
Kidney cancer 8 | 2,613
Liver Cirrhosis, Experimental 8 | 769
Toxic encephalopathy 8 | 141
pancreatic cancer 8 | 2,398
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Brain disease 7 | 96
Obesity 7 | 678
astrocytic glioma 7 | 2,597
diabetes mellitus 7 | 1,728
ulcerative colitis 7 | 1,819
Autistic Disorder 6 | 364
Autosomal recessive predisposition 6 | 1,442
Dementia 6 | 175
Hypertensive disease 6 | 292
Rheumatoid arthritis 6 | 1,191
cystic fibrosis 6 | 1,696
non-small cell lung cancer 6 | 2,890
Amphetamine-Related Disorders 5 | 74
Anemia 5 | 365
Cardiomyopathies 5 | 110
Cerebrovascular disease 5 | 238
Coronary artery disease 5 | 268
Hyperalgesia 5 | 83
Inflammation 5 | 120
Kidney disease 5 | 430
Memory Disorders 5 | 40
Nerve Degeneration 5 | 121
Neuropathy 5 | 261
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
dermatomyositis 5 | 966
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
periodontitis 5 | 293
tuberculosis 5 | 2,010
Anxiety Disorders 4 | 38
Arthritis 4 | 290
Arthritis, Rheumatoid 4 | 174
Asthma 4 | 385
Atherosclerosis 4 | 291
Cholestasis 4 | 155
Cocaine Dependence 4 | 51
Common cold 4 | 69
Diarrhea 4 | 253
Duchenne muscular dystrophy 4 | 601
Endometriosis 4 | 540
Epilepsy 4 | 792
Fever 4 | 138
Liver cancer 4 | 604
Myocardial Infarction 4 | 151
Myocardial Ischemia 4 | 169
Narcolepsy 4 | 72
Nervous System Diseases 4 | 53
Pick disease 4 | 1,894
Pneumonia 4 | 174
Pulmonary Fibrosis 4 | 106
Reperfusion Injury 4 | 86
Tremor 4 | 113
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
nervous system disorder 4 | 53
pancreatic carcinoma 4 | 562
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
spina bifida 4 | 1,074

Tissue

Endocrine System 32 | 18,159
Nervous System 31 | 16,725
Female tissues 30 | 17,400
Male tissues 30 | 17,142
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678
Digestive Tract 29 | 17,369
Liver and Pancreas 29 | 16,750
Blood and immune system 28 | 16,909
Respiratory system 28 | 16,393
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 8 | 4,145
Transporter 5 | 473
GPCR 2 | 408
Kinase 1 | 634

WikiPathways Pathway

Monoamine Transport 32 | 32
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
Amphiphysin AMPH Tbio Non-IDG -2.66933 440.3 354
Tryptophan 5-hydroxylase 2 TPH2 Tchem Enzyme -2.44646 308.6 361
Interleukin-1 receptor type 1 IL1R1 Tclin Non-IDG -2.68139 387.6 620
Interleukin-1 beta IL1B Tclin Non-IDG -4.40738 24522.4 1588
Angiotensinogen AGT Tbio Non-IDG -3.24591 1711.3 695
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB Tbio Enzyme -1.13726 11.3 290
Tyrosine 3-monooxygenase TH Tclin Enzyme -3.49790 2144.6 1203
Dopamine beta-hydroxylase DBH Tchem Enzyme -2.92000 674.8 416
Tryptophan 2,3-dioxygenase TDO2 Tchem Enzyme -2.89113 773.6 193