Development Level

Tbio 12 | 10,625
Tclin 12 | 602
Tchem 8 | 1,890

IMPC Term

preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal gait 1 | 51
abnormal tooth morphology 1 | 24
absent teeth 1 | 4
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating glycerol... 1 | 11
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
preweaning lethality, complete... 1 | 633
sparse hair 1 | 6
thrombocytosis 1 | 23

Disease

glioblastoma 16 | 5,572
osteosarcoma 15 | 7,933
ovarian cancer 15 | 8,492
psoriasis 15 | 6,685
pilocytic astrocytoma 13 | 3,086
Cancer 12 | 2,346
Schizophrenia 12 | 503
medulloblastoma, large-cell 12 | 6,234
pediatric high grade glioma 12 | 2,712
lung cancer 11 | 4,473
Alzheimer's disease 10 | 644
Breast cancer 10 | 3,099
malignant mesothelioma 10 | 3,163
primitive neuroectodermal tumor 10 | 3,031
Parkinson's disease 9 | 364
atypical teratoid / rhabdoid tumor 9 | 4,369
interstitial cystitis 9 | 2,299
lung adenocarcinoma 9 | 2,714
lung carcinoma 9 | 2,844
oligodendroglioma 9 | 2,849
Seizures 8 | 95
Toxic encephalopathy 8 | 131
pancreatic cancer 8 | 2,300
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Carcinoma 7 | 2,147
Hypertension 7 | 293
astrocytoma 7 | 1,493
atypical teratoid/rhabdoid tumor 7 | 1,095
ulcerative colitis 7 | 2,087
Attention deficit hyperactivity disorder 6 | 156
Autistic Disorder 6 | 320
Brain disease 6 | 84
Dementia 6 | 129
Major Depressive Disorder 6 | 106
Obesity 6 | 616
Rheumatoid Arthritis 6 | 1,171
cystic fibrosis 6 | 1,670
diabetes mellitus 6 | 1,663
posterior fossa group A ependymoma 6 | 1,511
Amphetamine-Related Disorders 5 | 74
Bipolar Disorder 5 | 266
Cardiomyopathies 5 | 90
Cerebrovascular disease 5 | 231
Coronary artery disease 5 | 240
Depressive disorder 5 | 48
Hyperalgesia 5 | 71
Kidney disease 5 | 397
Liver Cirrhosis, Experimental 5 | 108
Memory Disorders 5 | 36
Nerve Degeneration 5 | 73
adrenocortical carcinoma 5 | 1,427
breast carcinoma 5 | 1,614
dermatomyositis 5 | 967
group 3 medulloblastoma 5 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
non-small cell lung cancer 5 | 2,798
periodontitis 5 | 269
tuberculosis 5 | 1,563
Anemia 4 | 252
Anxiety Disorders 4 | 37
Arthritis 4 | 248
Asthma 4 | 349
Atherosclerosis 4 | 275
Common cold 4 | 63
Diarrhea 4 | 155
Duchenne muscular dystrophy 4 | 602
Endometriosis 4 | 535
Fever 4 | 34
Gilles de la Tourette syndrome 4 | 47
Hypertensive disease 4 | 193
Hypotension 4 | 53
Inflammation 4 | 109
Myocardial Infarction 4 | 126
Myocardial Ischemia 4 | 169
Narcolepsy 4 | 69
Neuropathy 4 | 210
Oppositional defiant disorder 4 | 16
Pick disease 4 | 1,893
aldosterone-producing adenoma 4 | 664
astrocytic glioma 4 | 2,241
ependymoma 4 | 2,514
group 4 medulloblastoma 4 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
invasive ductal carcinoma 4 | 2,950
medulloblastoma 4 | 1,524
nervous system disorder 4 | 53
pancreatic carcinoma 4 | 567
posterior fossa group B ependymoma 4 | 1,530
primary pancreatic ductal adenocarcinoma 4 | 1,271
sonic hedgehog group medulloblastoma 4 | 1,482
spina bifida 4 | 1,064
Allergic rhinitis 3 | 92
Brain Ischemia 3 | 87
Heart disease 3 | 279
Hypersensitivity reaction type II disease 3 | 235
Multiple Sclerosis 3 | 498
Peripheral Neuropathy 3 | 303
Reperfusion Injury 3 | 84
acute quadriplegic myopathy 3 | 1,157

Tissue

Blood and immune system 32 | 17,995
Cardiovascular System 32 | 17,958
Digestive Tract 32 | 18,473
Endocrine System 32 | 18,512
Female tissues 32 | 18,647
Liver and Pancreas 32 | 18,136
Male tissues 32 | 17,969
Nervous System 32 | 18,561
Skin and soft tissues 32 | 18,115
Urinary Tract 32 | 18,444
Respiratory system 31 | 17,484

Target Family

Non-IDG 16 | 11,969
Enzyme 8 | 4,146
Transporter 5 | 473
GPCR 2 | 408
Kinase 1 | 634

WikiPathways Pathway

Monoamine Transport 32 | 32
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 257 | 257
Circadian rythm related genes 200 | 200
Integrated Pancreatic Cancer P... 192 | 192
Focal Adhesion 190 | 190
Metapathway biotransformation 172 | 172
MAPK Signaling Pathway 167 | 167
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
Myometrial Relaxation and Cont... 157 | 157
Sudden Infant Death Syndrome (... 157 | 157
Allograft Rejection 156 | 156
Integrated Breast Cancer Pathw... 152 | 152
Calcium Regulation in the Card... 150 | 150
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Signaling Pathways in Glioblas... 83 | 83
MicroRNAs in cardiomyocyte hyp... 82 | 82
Alzheimers Disease 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Arrhythmogenic Right Ventricul... 74 | 74
Peptide GPCRs 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Wnt Signaling Pathway 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
IL-1 signaling pathway 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Copper homeostasis 54 | 54
ErbB Signaling Pathway 54 | 54
IL-4 Signaling Pathway 54 | 54
Interferon type I signaling pa... 54 | 54
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54
Apoptosis-related network due ... 53 | 53
Cardiac Hypertrophic Response 53 | 53
Cardiac Progenitor Differentia... 53 | 53
Synaptic Vesicle Pathway 51 | 51
Translation Factors 51 | 51
Wnt Signaling Pathway Netpath 51 | 51

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synapsin-1 SYN1 Tbio Non-IDG -2.85684 687.9 716
Histamine H3 receptor HRH3 Tclin GPCR -2.74979 555.6 281
Angiotensinogen AGT Tchem Non-IDG -3.23867 1673.4 609
Tryptophan 5-hydroxylase 2 TPH2 Tchem Enzyme -2.42413 295.6 323
Interleukin-1 receptor type 1 IL1R1 Tclin Non-IDG -2.65608 362.9 482
Amphiphysin AMPH Tbio Non-IDG -2.65369 426.2 341
Secretory carrier-associated membrane protein 2 SCAMP2 Tbio Non-IDG -1.03454 11.0 110
Interleukin-1 beta IL1B Tclin Non-IDG -4.37376 22444.2 1345