Development Level

Tclin 27 | 613
Tchem 6 | 1,598

Collection

GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
decreased total body fat amoun... 2 | 207
hyperactivity 2 | 148
increased circulating sodium l... 2 | 71
abnormal tail length 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased anxiety-related resp... 1 | 12
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased circulating chloride... 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 27 | 11,493
Schizophrenia 27 | 1,160
Parkinson's disease 21 | 392
psoriasis 19 | 6,694
Bipolar Disorder 18 | 666
Mood Disorders 18 | 184
Depressive disorder 17 | 409
Major Depressive Disorder 16 | 301
Migraine 14 | 83
Attention deficit hyperactivity disorder 13 | 278
Mental Depression 13 | 333
Nasal discharge 12 | 24
Alcoholic Intoxication, Chronic 11 | 289
Nasal congestion 11 | 21
Alcohol dependence 10 | 107
Asthma 10 | 385
Autistic Disorder 10 | 364
Unipolar Depression 10 | 250
glioblastoma 10 | 5,792
Allergic rhinitis 9 | 94
Bronchitis 9 | 43
Hypertensive disorder 9 | 56
Open-angle glaucoma 9 | 27
Orthostatic hypotension 9 | 9
Pulmonary emphysema 9 | 48
Substance abuse 9 | 59
ependymoma 9 | 4,679
medulloblastoma, large-cell 9 | 6,241
osteosarcoma 9 | 7,950
Acute exacerbation of asthma 8 | 14
Asthma management 8 | 19
Bronchiectasis 8 | 64
General anesthesia 8 | 53
Hypertension 8 | 396
Low blood pressure 8 | 9
Obesity 8 | 678
diabetes mellitus 8 | 1,728
oligodendroglioma 8 | 2,850
ovarian cancer 8 | 8,520
primitive neuroectodermal tumor 8 | 3,035
Administration of Local Anesthetic Nerve Block 7 | 14
Allergic Reactions 7 | 7
Allergic conjunctivitis 7 | 22
Astrocytoma, Pilocytic 7 | 3,081
Cocaine-Related Disorders 7 | 92
Common cold 7 | 67
Dyspnea 7 | 76
Epilepsy 7 | 792
Exacerbation of asthma 7 | 11
Gilles de la Tourette syndrome 7 | 47
Hypotension 7 | 82
Local anesthesia, by infiltration 7 | 14
Red eye 7 | 7
Seizures 7 | 596
Sneezing 7 | 12
Wheezing 7 | 7
adult high grade glioma 7 | 3,801
anaphylaxis 7 | 11
obsessive-compulsive disorder 7 | 61
Alzheimer's disease 6 | 658
Amphetamine-Related Disorders 6 | 74
Cerebral Ischemia 6 | 37
Cerebrovascular disease 6 | 238
Chronic obstructive lung disease 6 | 6
Dermal Necrosis 6 | 6
Diagnostic Test for Pheochromocytoma 6 | 6
Fever 6 | 138
Gastric ulcer 6 | 33
Hyperprolactinemia 6 | 27
Hypertension Secondary to Pheochromocytoma 6 | 6
Hypertensive Emergencies 6 | 10
Migraine Prevention 6 | 23
Ocular hypertension 6 | 42
Paroxysmal hypertension 6 | 6
Peptic Ulcer 6 | 27
Peripheral vascular disease 6 | 87
Pheochromocytoma 6 | 24
Prevention of Hypertension in Pheochromocytoma 6 | 6
Vasomotor rhinitis 6 | 12
astrocytic glioma 6 | 2,597
atypical teratoid / rhabdoid tumor 6 | 5,112
malignant mesothelioma 6 | 3,232
Acromegaly 5 | 51
Amnestic disorder 5 | 35
Chronic schizophrenia 5 | 16
Cluster headache syndrome 5 | 8
Cocaine abuse 5 | 19
Cough 5 | 23
Dilated pupil 5 | 6
Gastrointestinal Radiography Adjunct 5 | 11
Hyperactive behavior 5 | 91
Hyperkinesis 5 | 32
Irritable bowel syndrome 5 | 60
Memory Disorders 5 | 40
Parkinsonism 5 | 18
Rhinitis 5 | 54
Spasticity 5 | 26
Substance Withdrawal Syndrome 5 | 55
Tremor 5 | 113
Urinary Incontinence 5 | 50

Tissue

Endocrine System 32 | 18,159
Nervous System 31 | 16,725
Digestive Tract 30 | 17,369
Female tissues 30 | 17,400
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Blood and immune system 26 | 16,909
Urinary Tract 24 | 16,678
Cardiovascular System 20 | 15,192

Target Family

GPCR 33 | 408

WikiPathways Pathway

Monoamine GPCRs 33 | 33
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Histamine H2 receptor HRH2 Tclin GPCR -3.21267 1595.1 244
Alpha-1D adrenergic receptor ADRA1D Tclin GPCR -2.25789 174.5 120
5-hydroxytryptamine receptor 6 HTR6 Tchem GPCR -2.31880 213.2 64
5-hydroxytryptamine receptor 1F HTR1F Tchem GPCR -2.39159 244.1 131
Muscarinic acetylcholine receptor M1 CHRM1 Tclin GPCR -2.16159 140.8 222
Alpha-1B adrenergic receptor ADRA1B Tclin GPCR -2.30594 201.5 364
Histamine H1 receptor HRH1 Tclin GPCR -3.02485 1031.1 393
Alpha-1A adrenergic receptor ADRA1A Tclin GPCR -2.18682 155.5 236