Development Level

Tchem 14 | 1,388
Tbio 13 | 11,651
Tclin 7 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

increased circulating alkaline... 3 | 122
decreased circulating sodium l... 2 | 22
increased circulating free fat... 2 | 20
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal heart left ventricle ... 1 | 16
abnormal skin condition 1 | 6
abnormal tooth morphology 1 | 24
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 26 | 11,493
psoriasis 22 | 6,694
ovarian cancer 21 | 8,520
Cancer 18 | 2,499
Schizophrenia 17 | 1,160
glioblastoma 16 | 5,792
medulloblastoma, large-cell 16 | 6,241
Bipolar Disorder 15 | 666
lung cancer 15 | 4,740
osteosarcoma 15 | 7,950
Depressive disorder 14 | 409
Mental Depression 14 | 333
atypical teratoid / rhabdoid tumor 13 | 5,112
diabetes mellitus 12 | 1,728
Major Depressive Disorder 11 | 301
Obesity 11 | 678
ependymoma 11 | 4,679
invasive ductal carcinoma 11 | 2,951
Breast cancer 10 | 3,578
Mood Disorders 10 | 184
group 3 medulloblastoma 10 | 4,104
malignant mesothelioma 10 | 3,232
lung adenocarcinoma 9 | 2,716
Alzheimer's disease 8 | 658
Parkinson's disease 8 | 392
Unipolar Depression 8 | 250
adult high grade glioma 8 | 3,801
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
spina bifida 8 | 1,074
tuberculosis 8 | 2,010
Prostatic Neoplasms 7 | 495
Seasonal affective disorder 7 | 28
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
non-small cell lung cancer 7 | 2,890
subependymal giant cell astrocytoma 7 | 2,287
Alcoholic Intoxication, Chronic 6 | 289
Astrocytoma, Pilocytic 6 | 3,081
Breast Neoplasms 6 | 445
Coronary artery disease 6 | 268
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
Diabetes Mellitus, Type 2 6 | 142
Hypertension 6 | 396
Hypertensive disease 6 | 292
Kidney cancer 6 | 2,613
Leukemia, Myelogenous, Chronic, BCR-ABL Positive 6 | 20
Mammary Neoplasms 6 | 425
Myeloid Leukemia, Chronic 6 | 23
Rheumatoid arthritis 6 | 1,191
Toxic encephalopathy 6 | 141
adrenocortical carcinoma 6 | 1,428
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
pituitary cancer 6 | 1,972
Acute kidney injury 5 | 70
Autosomal recessive predisposition 5 | 1,442
Cardiomegaly 5 | 116
Cerebrovascular disease 5 | 238
Dementia 5 | 175
Glaucoma 5 | 239
Heart disease 5 | 306
Hepatomegaly 5 | 285
Liver Cirrhosis, Experimental 5 | 769
acute quadriplegic myopathy 5 | 1,158
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Alzheimer Disease 4 | 83
Atherosclerosis 4 | 291
Atrial Fibrillation 4 | 124
Cardiovascular Diseases 4 | 59
Cocaine Dependence 4 | 51
Diabetes Mellitus, Experimental 4 | 108
Endometriosis 4 | 540
Heart failure 4 | 162
Hyperglycemia 4 | 137
Liver disease 4 | 237
Myocardial Ischemia 4 | 169
Pick disease 4 | 1,894
Renal Cell Carcinoma 4 | 214
astrocytic glioma 4 | 2,597
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
interstitial lung disease 4 | 298
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Abortion, Spontaneous 3 | 109
Spontaneous abortion 3 | 113
Type 2 diabetes mellitus 3 | 272
Vascular disease 3 | 319
aldosterone-producing adenoma 3 | 665
chronic rhinosinusitis 3 | 512
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484

Tissue

Blood and immune system 33 | 16,909
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Skin and soft tissues 33 | 17,230
Nervous System 32 | 16,725
Urinary Tract 32 | 16,678
Respiratory system 31 | 16,393
Cardiovascular System 29 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 7 | 4,145
Kinase 6 | 634
GPCR 3 | 408
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

WikiPathways Pathway

Melatonin metabolism and effec... 34 | 34
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
MECP2 and Associated Rett Synd... 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Cytochrome P450 1A1 CYP1A1 Tchem Non-IDG -3.54987 3641.5 384
Period circadian protein homolog 2 PER2 Tchem Non-IDG -2.67778 457.4 219
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976
Circadian locomoter output cycles protein kaput CLOCK Tbio TF/Epigenetic -2.63013 392.7 323
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -3.00390 610.8 955
Period circadian protein homolog 1 PER1 Tbio Non-IDG -1.86449 71.4 178
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.58807 348.8 804