Development Level

Tbio 44 | 11,445
Tchem 12 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 8 | 979
decreased total body fat amoun... 3 | 207
preweaning lethality, incomple... 3 | 499
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral content 2 | 151
decreased lean body mass 2 | 135
increased mean corpuscular hem... 2 | 96
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
aorta stenosis 1 | 2
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
no spontaneous movement 1 | 1
prenatal lethality prior to he... 1 | 87
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

Carcinoma 47 | 11,493
ovarian cancer 36 | 8,520
medulloblastoma, large-cell 34 | 6,241
lung cancer 33 | 4,740
osteosarcoma 32 | 7,950
ependymoma 30 | 4,679
glioblastoma 28 | 5,792
group 3 medulloblastoma 28 | 4,104
psoriasis 28 | 6,694
Cancer 27 | 2,499
atypical teratoid / rhabdoid tumor 27 | 5,112
oligodendroglioma 24 | 2,850
Schizophrenia 23 | 1,160
malignant mesothelioma 23 | 3,232
Astrocytoma, Pilocytic 22 | 3,081
Kidney cancer 20 | 2,613
primitive neuroectodermal tumor 20 | 3,035
Breast cancer 19 | 3,578
adult high grade glioma 19 | 3,801
subependymal giant cell astrocytoma 19 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
Intellectual disability 17 | 1,016
Pick disease 16 | 1,894
Epilepsy 15 | 792
astrocytoma 15 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
Bipolar Disorder 14 | 666
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
Seizures 13 | 596
invasive ductal carcinoma 13 | 2,951
pituitary cancer 13 | 1,972
Autistic Disorder 12 | 364
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
astrocytic glioma 12 | 2,597
lung adenocarcinoma 12 | 2,716
lung carcinoma 12 | 2,843
non-small cell lung cancer 12 | 2,890
Depressive disorder 11 | 409
Major Depressive Disorder 11 | 301
Parkinson's disease 11 | 392
group 4 medulloblastoma 11 | 1,855
Alzheimer's disease 10 | 658
Obesity 10 | 678
adrenocortical carcinoma 10 | 1,428
diabetes mellitus 10 | 1,728
Alcoholic Intoxication, Chronic 9 | 289
Cocaine-Related Disorders 9 | 92
Mental Depression 9 | 333
Mood Disorders 9 | 184
Unipolar Depression 9 | 250
breast carcinoma 9 | 1,638
Acquired scoliosis 8 | 281
Breast Neoplasms 8 | 445
Carcinoma, Hepatocellular 8 | 228
Cryptorchidism 8 | 296
Curvature of spine 8 | 282
Liver carcinoma 8 | 240
Mammary Neoplasms 8 | 425
Muscle hypotonia 8 | 571
Psychotic Disorders 8 | 151
Short stature 8 | 531
Small head 8 | 374
Toxic encephalopathy 8 | 141
pancreatic cancer 8 | 2,398
pediatric high grade glioma 8 | 1,064
Delayed speech and language development 7 | 112
Down syndrome 7 | 499
Hypoplastic mandible condyle 7 | 275
Language Delay 7 | 112
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Rett syndrome 7 | 18
Speech Delay 7 | 112
Speech impairment 7 | 112
acute quadriplegic myopathy 7 | 1,158
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
juvenile dermatomyositis 7 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Autism spectrum disorder 6 | 101
Autosomal recessive predisposition 6 | 1,442
Concave bridge of nose 6 | 195
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Feeding difficulties in infancy 6 | 175
Immune system cancer 6 | 140
Kidney disease 6 | 430
Melanoma 6 | 711
Multiple Sclerosis 6 | 540
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
ductal carcinoma in situ 6 | 1,745
primary Sjogren syndrome 6 | 735

Tissue

Endocrine System 61 | 18,159
Nervous System 60 | 16,725
Female tissues 59 | 17,400
Digestive Tract 58 | 17,369
Skin and soft tissues 58 | 17,230
Blood and immune system 57 | 16,909
Male tissues 56 | 17,142
Liver and Pancreas 55 | 16,750
Respiratory system 54 | 16,393
Urinary Tract 54 | 16,678
Cardiovascular System 52 | 15,192

Target Family

Non-IDG 24 | 12,091
Transcription Factor 17 | 1,400
Enzyme 9 | 4,145
Kinase 5 | 634
Ion Channel 4 | 344
Epigenetic 2 | 242
GPCR 1 | 408

WikiPathways Pathway

MECP2 and Associated Rett Synd... 62 | 62
PI3K-Akt Signaling Pathway 338 | 338
Focal Adhesion-PI3K-Akt-mTOR-s... 303 | 303
GPCRs, Class A Rhodopsin-like 258 | 258
MAPK Signaling Pathway 245 | 245
VEGFA-VEGFR2 Signaling Pathway 235 | 235
Focal Adhesion 206 | 206
Circadian rythm related genes 200 | 200
Vitamin D Receptor Pathway 196 | 196
Ras Signaling 182 | 182
Metapathway biotransformation ... 172 | 172
Allograft Rejection 168 | 168
Chemokine signaling pathway 164 | 164
EGF/EGFR Signaling Pathway 162 | 162
Insulin Signaling 160 | 160
EMT transition in Colorectal C... 159 | 159
Myometrial Relaxation and Cont... 159 | 159
Sudden Infant Death Syndrome (... 157 | 157
Calcium Regulation in the Card... 152 | 152
Integrated Breast Cancer Pathw... 152 | 152
Regulation of Actin Cytoskelet... 149 | 149
Mesodermal Commitment Pathway 147 | 147
Brain-Derived Neurotrophic Fac... 144 | 144
NRF2 pathway 143 | 143
Endoderm Differentiation 141 | 141
Ectoderm Differentiation 138 | 138
Regulation of toll-like recept... 138 | 138
Wnt Signaling Pathway 135 | 135
Angiopoietin Like Protein 8 Re... 132 | 132
TGF-beta Signaling Pathway 132 | 132
Adipogenesis 130 | 130
Proteasome Degradation 129 | 129
mRNA Processing 125 | 125
ESC Pluripotency Pathways 116 | 116
Spinal Cord Injury 116 | 116
DNA Damage Response (only ATM ... 112 | 112
Senescence and Autophagy in Ca... 106 | 106
Cell Cycle 104 | 104
Electron Transport Chain 103 | 103
Neural Crest Differentiation 101 | 101
Toll-like Receptor Signaling P... 101 | 101
Wnt Signaling Pathway and Plur... 101 | 101
Integrin-mediated Cell Adhesio... 100 | 100
B Cell Receptor Signaling Path... 97 | 97
Corticotropin-releasing hormon... 95 | 95
G Protein Signaling Pathways 94 | 94
Amino Acid metabolism 92 | 92
Apoptosis Modulation and Signa... 92 | 92
GPCRs, Other 92 | 92
TNF alpha Signaling Pathway 92 | 92
T-Cell antigen Receptor (TCR) ... 90 | 90
Androgen receptor signaling pa... 89 | 89
Cytoplasmic Ribosomal Proteins 89 | 89
Retinoblastoma (RB) in Cancer 87 | 87
Apoptosis 86 | 86
Selenium Micronutrient Network 85 | 85
Pyrimidine metabolism 84 | 84
Signaling Pathways in Glioblas... 83 | 83
Alzheimers Disease 82 | 82
MicroRNAs in cardiomyocyte hyp... 82 | 82
DNA IR-damage and cellular res... 80 | 80
Notch Signaling Pathway 79 | 79
Leptin signaling pathway 76 | 76
Prolactin Signaling Pathway 76 | 76
Peptide GPCRs 75 | 75
Arrhythmogenic Right Ventricul... 74 | 74
Chromosomal and microsatellite... 74 | 74
miRNA Regulation of DNA Damage... 73 | 73
Primary Focal Segmental Glomer... 72 | 72
Type II interferon signaling (... 71 | 71
DNA Damage Response 69 | 69
G1 to S cell cycle control 69 | 69
Parkin-Ubiquitin Proteasomal S... 69 | 69
Sterol Regulatory Element-Bind... 69 | 69
AMP-activated Protein Kinase (... 68 | 68
Human Thyroid Stimulating Horm... 68 | 68
PPAR signaling pathway 67 | 67
Rac1/Pak1/p38/MMP-2 pathway 67 | 67
AGE/RAGE pathway 66 | 66
Association Between Physico-Ch... 66 | 66
Folate Metabolism 65 | 65
Oncostatin M Signaling Pathway 65 | 65
Lung fibrosis 64 | 64
Pathways Affected in Adenoid C... 64 | 64
Endometrial cancer 63 | 63
Endochondral Ossification 62 | 62
Oxidation by Cytochrome P450 62 | 62
TYROBP Causal Network 61 | 61
Oxidative phosphorylation 60 | 60
T-Cell antigen Receptor (TCR) ... 60 | 60
Complement and Coagulation Cas... 59 | 59
Kit receptor signaling pathway 59 | 59
RIG-I-like Receptor Signaling 59 | 59
Preimplantation Embryo 58 | 58
DNA IR-Double Strand Breaks (D... 56 | 56
IL-1 signaling pathway 55 | 55
MET in type 1 papillary renal ... 55 | 55
RANKL/RANK (Receptor activator... 55 | 55
Pathogenic Escherichia coli in... 54 | 54
TGF-beta Receptor Signaling 54 | 54

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myelin transcription factor 1 MYT1 Tchem Transcription Factor -1.20241 19.8 218
Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 Tbio Ion Channel -1.74365 53.9 92
Methylcytosine dioxygenase TET3 TET3 Tbio Enzyme -1.96016 82.2 167
Peptidyl-prolyl cis-trans isomerase FKBP5 FKBP5 Tchem Enzyme -2.52114 348.1 299
POU domain, class 4, transcription factor 1 POU4F1 Tbio Transcription Factor -2.19846 154.8 107
Somatostatin SST Tbio Non-IDG -4.14886 13572.0 397
Methylcytosine dioxygenase TET1 TET1 Tbio Enzyme -2.97441 911.4 193
40S ribosomal protein S6 RPS6 Tbio Non-IDG -2.76789 501.6 920
Transcriptional repressor CTCF CTCF Tbio Transcription Factor -2.87726 746.5 284
CCAAT/enhancer-binding protein delta CEBPD Tbio Transcription Factor -2.49029 299.9 179